38 research outputs found
LAPAROSCOPIC SURGERY IN TREATMENT OF ENDOMETRIAL CANCER (RESULTS OF 7-YEAR CLINICAL EXPERIENCE AT THE N.N. PETROV NATIONAL MEDICAL RESEARCH ONCOLOGY CENTER)
Introduction. The main method of treatment of endometrial cancer, the most common oncological disease, is surgery. Introduction of high-tech operations into gynecological practice promoted active use of laparoscopy in treatment of malignant tumors of the endometrium.Objective. To evaluate effectiveness of video endoscopic surgery in treatment of endometrial cancer.Materials and methods. In the period from 2010 to 2016, 1127 patients with endometrial cancer underwent surgery using video endoscopic complex with high resolution cameras at the N.N. Petrov National Medical Research Oncology Center, Ministry of Health of Russia.Results.Β Using video endoscopic technology, excision of the uterus with appendages was performed in 588 (52.3 %) patients, excision of the uterus with appendages and pelvic lymph node dissection was performed in 523 (46.4 %) patients including 16 (1.4 %) patients with serous and papillary serous forms of endometrial cancer who also underwent omentectomy. No intraoperative complications were observed. In the majority of patients, postoperative period was characterized by early activization, satisfactory intestinal peristalsis on day 1, minimal complications, absence of contraindications for adjuvant beam therapy.Conclusion. Video endoscopic technology is a modern method of surgical treatment allowing to perform the full scope of planned radical surgical intervention in patients with endometrial cancer irrespectively of age and concomitant disorders with minimal traumatization, risk of intraand postoperative complications as well as favorable and fast rehabilitation period
The number of transmission channels through a single-molecule junction
We calculate transmission eigenvalue distributions for Pt-benzene-Pt and
Pt-butadiene-Pt junctions using realistic state-of-the-art many-body
techniques. An effective field theory of interacting -electrons is used to
include screening and van der Waals interactions with the metal electrodes. We
find that the number of dominant transmission channels in a molecular junction
is equal to the degeneracy of the molecular orbital closest to the metal Fermi
level.Comment: 9 pages, 8 figure
ΠΠΠΠ ΠΠΠΠΠΠΠ ΠΠΠΠ«Π ΠΠΠ£Π₯ΠΠΠ Π¨ΠΠΠΠ ΠΠΠ’ΠΠ
The purpose of the study was to summarize the available data on etiology, diagnosis, clinical symptoms and signs as well as on various approaches to the treatment of neuroendocrine cervical tumors.Material and Methods. The relevant sources were searched in the PubMed and cochrane Library systems, and publications from 1980 to 2019 were analyzed, 53 of which were used to write this review. We also included 6 case reports from N.N. Petrov National Research Center of Oncology.Results. Neuroendocrine tumors (NETs) are extremely rare and aggressive malignancies of the female genital tract, among which NETs of the cervix are the most common. Due to the rarity of these tumors, there are currently no treatment standards based on prospective, well-planned clinical trials. For these reasons, NETs present a significant therapeutic challenge for clinicians. Case reports. Six patients ranged in age from 32 to 71 years, with a median age of 46 years, were diagnosed with large-cell neuroendocrine carcinoma (4 patients) and small-cell neuroendocrine carcinoma (2 patients). One patient with stage IIIA dropped out of the follow-up schedule. Out of 5 followed up patients, 2 patients with stage IIIA and IIB died of disease progression after 6 and 11 months, respectively. One patient with stage IB1 is in remission for 16 months. Two patients with stage IIB continue to receive primary treatment.Conclusion. Neuroendocrine carcinoma of the cervix is a rare variant of cervical cancer. The choice of treatment options is decided only by a multidisciplinary team of doctors, and further research is required.Β Π¦Π΅Π»Ρ ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΡ β ΠΎΠ±ΠΎΠ±ΡΠ΅Π½ΠΈΠ΅ ΠΈΠΌΠ΅ΡΡΠΈΡ
ΡΡ Π΄Π°Π½Π½ΡΡ
ΠΎΠ± ΠΎΡΠΎΠ±Π΅Π½Π½ΠΎΡΡΠΈ ΡΡΠΈΠΎΠ»ΠΎΠ³ΠΈΠΈ ΠΈ Π΄ΠΈΠ°Π³Π½ΠΎΡΡΠΈΠΊΠΈ, ΠΊΠ»ΠΈΠ½ΠΈΡΠ΅ΡΠΊΠΎΠΉ ΠΊΠ°ΡΡΠΈΠ½Π΅ ΠΈ ΡΠ°Π·Π»ΠΈΡΠ½ΡΡ
ΠΏΠΎΠ΄Ρ
ΠΎΠ΄Π°Ρ
Π² Π»Π΅ΡΠ΅Π½ΠΈΠΈ Π½Π΅ΠΉΡΠΎΡΠ½Π΄ΠΎΠΊΡΠΈΠ½Π½ΡΡ
ΠΎΠΏΡΡ
ΠΎΠ»Π΅ΠΉ ΡΠ΅ΠΉΠΊΠΈ ΠΌΠ°ΡΠΊΠΈ.ΠΠ°ΡΠ΅ΡΠΈΠ°Π» ΠΈ ΠΌΠ΅ΡΠΎΠ΄Ρ. ΠΠΎΠΈΡΠΊ ΡΠΎΠΎΡΠ²Π΅ΡΡΡΠ²ΡΡΡΠΈΡ
ΠΈΡΡΠΎΡΠ½ΠΈΠΊΠΎΠ² ΠΏΡΠΎΠΈΠ·Π²ΠΎΠ΄ΠΈΠ»ΡΡ Π² ΡΠΈΡΡΠ΅ΠΌΠ°Ρ
PubMed ΠΈ cochrane Library, Π°Π½Π°Π»ΠΈΠ·ΠΈΡΠΎΠ²Π°Π»ΠΈΡΡ ΠΏΡΠ±Π»ΠΈΠΊΠ°ΡΠΈΠΈ Ρ 1980 ΠΏΠΎ 2019 Π³., 53 ΠΈΠ· ΠΊΠΎΡΠΎΡΡΡ
Π±ΡΠ»ΠΈ ΠΈΡΠΏΠΎΠ»ΡΠ·ΠΎΠ²Π°Π½Ρ Π΄Π»Ρ Π½Π°ΠΏΠΈΡΠ°Π½ΠΈΡ Π΄Π°Π½Π½ΠΎΠ³ΠΎ ΠΎΠ±Π·ΠΎΡΠ°. Π’Π°ΠΊΠΆΠ΅ Π² ΠΏΡΠ±Π»ΠΈΠΊΠ°ΡΠΈΠΈ ΠΎΡΠ²Π΅ΡΠ΅Π½Ρ 6 ΡΠ»ΡΡΠ°Π΅Π² ΡΠΎΠ±ΡΡΠ²Π΅Π½Π½ΡΡ
Π½Π°Π±Π»ΡΠ΄Π΅Π½ΠΈΠΉ Π² ΠΠΠΠ¦ ΠΎΠ½ΠΊΠΎΠ»ΠΎΠ³ΠΈΠΈ ΠΈΠΌ. Π.Π. ΠΠ΅ΡΡΠΎΠ²Π°.Π Π΅Π·ΡΠ»ΡΡΠ°ΡΡ. ΠΠ΅ΠΉΡΠΎΡΠ½Π΄ΠΎΠΊΡΠΈΠ½Π½ΡΠ΅ ΠΎΠΏΡΡ
ΠΎΠ»ΠΈ (ΠΠΠ) ΡΠ²Π»ΡΡΡΡΡ ΠΊΡΠ°ΠΉΠ½Π΅ ΡΠ΅Π΄ΠΊΠΈΠΌΠΈ ΠΈ Π°Π³ΡΠ΅ΡΡΠΈΠ²Π½ΡΠΌΠΈ Π·Π»ΠΎΠΊΠ°ΡΠ΅ΡΡΠ²Π΅Π½Π½ΡΠΌΠΈ Π½ΠΎΠ²ΠΎΠΎΠ±ΡΠ°Π·ΠΎΠ²Π°Π½ΠΈΡΠΌΠΈ Π½ΠΈΠΆΠ½Π΅Π³ΠΎ ΠΆΠ΅Π½ΡΠΊΠΎΠ³ΠΎ ΠΏΠΎΠ»ΠΎΠ²ΠΎΠ³ΠΎ ΡΡΠ°ΠΊΡΠ°, ΡΡΠ΅Π΄ΠΈ ΠΊΠΎΡΠΎΡΡΡ
ΠΠΠ ΡΠ΅ΠΉΠΊΠΈ ΠΌΠ°ΡΠΊΠΈ Π²ΡΡΡΠ΅ΡΠ°ΡΡΡΡ ΡΠ°ΡΠ΅ Π²ΡΠ΅Π³ΠΎ. ΠΠ·-Π·Π° ΡΠ΅Π΄ΠΊΠΎΡΡΠΈ ΡΡΠΈΡ
ΠΎΠΏΡΡ
ΠΎΠ»Π΅ΠΉ Π² Π½Π°ΡΡΠΎΡΡΠ΅Π΅ Π²ΡΠ΅ΠΌΡ ΠΎΡΡΡΡΡΡΠ²ΡΡΡ ΡΡΠ°Π½Π΄Π°ΡΡΡ ΠΏΠΎ Π»Π΅ΡΠ΅Π½ΠΈΡ, ΠΎΡΠ½ΠΎΠ²Π°Π½Π½ΡΠ΅ Π½Π° ΠΏΡΠΎΡΠΏΠ΅ΠΊΡΠΈΠ²Π½ΡΡ
, Ρ
ΠΎΡΠΎΡΠΎ ΡΠΏΠ»Π°Π½ΠΈΡΠΎΠ²Π°Π½Π½ΡΡ
ΠΊΠ»ΠΈΠ½ΠΈΡΠ΅ΡΠΊΠΈΡ
ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΡΡ
. ΠΠΎ ΡΡΠΈΠΌ ΠΏΡΠΈΡΠΈΠ½Π°ΠΌ ΠΠΠ ΠΏΡΠ΅Π΄ΡΡΠ°Π²Π»ΡΡΡ ΡΠΎΠ±ΠΎΠΉ Π°ΠΊΡΡΠ°Π»ΡΠ½ΡΡ ΠΏΡΠΎΠ±Π»Π΅ΠΌΡ Π΄Π»Ρ ΠΊΠ»ΠΈΠ½ΠΈΡΠΈΡΡΠΎΠ². ΠΠΎ Π΄Π°Π½Π½ΡΠΌ ΡΠΎΠ±ΡΡΠ²Π΅Π½Π½ΡΡ
Π½Π°Π±Π»ΡΠ΄Π΅Π½ΠΈΠΉ, Π² ΠΠΠΠ¦ ΠΎΠ½ΠΊΠΎΠ»ΠΎΠ³ΠΈΠΈ ΠΈΠΌ. Π.Π. ΠΠ΅ΡΡΠΎΠ²Π° ΡΡΠ΅Π΄Π½ΠΈΠΉ Π²ΠΎΠ·ΡΠ°ΡΡ ΠΏΠ°ΡΠΈΠ΅Π½ΡΠΎΠΊ (n=6) ΡΠΎΡΡΠ°Π²ΠΈΠ» 46 Π»Π΅Ρ, Π²ΠΎΠ·ΡΠ°ΡΡΠ½ΠΎΠΉ Π΄ΠΈΠ°ΠΏΠ°Π·ΠΎΠ½ 32β71 Π³ΠΎΠ΄; ΡΠ°ΡΠΏΡΠ΅Π΄Π΅Π»Π΅Π½ΠΈΠ΅ ΠΏΠΎ Π³ΠΈΡΡΠΎΡΠΈΠΏΡ: ΠΊΡΡΠΏΠ½ΠΎΠΊΠ»Π΅ΡΠΎΡΠ½Π°Ρ Π½Π΅ΠΉΡΠΎΡΠ½Π΄ΠΎΠΊΡΠΈΠ½Π½Π°Ρ ΠΊΠ°ΡΡΠΈΠ½ΠΎΠΌΠ° β 4, ΠΌΠ΅Π»ΠΊΠΎΠΊΠ»Π΅ΡΠΎΡΠ½Π°Ρ Π½Π΅ΠΉΡΠΎΡΠ½Π΄ΠΎΠΊΡΠΈΠ½Π½Π°Ρ ΠΊΠ°ΡΡΠΈΠ½ΠΎΠΌΠ° β 2 ΠΏΠ°ΡΠΈΠ΅Π½ΡΠΊΠΈ. ΠΠ΄Π½Π° ΠΏΠ°ΡΠΈΠ΅Π½ΡΠΊΠ° Ρ IIIA ΡΡΠ°Π΄ΠΈΠ΅ΠΉ Π²ΡΠ±ΡΠ»Π° ΠΈΠ· Π½Π°Π±Π»ΡΠ΄Π΅Π½ΠΈΡ; ΠΈΠ· 5 ΠΏΡΠΎΡΠ»Π΅ΠΆΠ΅Π½Π½ΡΡ
2 ΠΏΠ°ΡΠΈΠ΅Π½ΡΠΊΠΈ Ρ IIIA ΠΈ IIB ΡΡΠ°Π΄ΠΈΠ΅ΠΉ ΡΠΌΠ΅ΡΠ»ΠΈ ΠΎΡ ΠΏΡΠΎΠ³ΡΠ΅ΡΡΠΈΡΠΎΠ²Π°Π½ΠΈΡ Π·Π°Π±ΠΎΠ»Π΅Π²Π°Π½ΠΈΡ ΡΠ΅ΡΠ΅Π· 6 ΠΈ 11 ΠΌΠ΅Ρ ΡΠΎΠΎΡΠ²Π΅ΡΡΡΠ²Π΅Π½Π½ΠΎ, 1 ΠΏΠ°ΡΠΈΠ΅Π½ΡΠΊΠ° Ρ IB1 ΡΡΠ°Π΄ΠΈΠ΅ΠΉ ΠΏΠΎΡΠ»Π΅ ΠΊΠΎΠΌΠ±ΠΈΠ½ΠΈΡΠΎΠ²Π°Π½Π½ΠΎΠ³ΠΎ Π»Π΅ΡΠ΅Π½ΠΈΡ Π½Π°Ρ
ΠΎΠ΄ΠΈΡΡΡ Π² ΡΠ΅ΠΌΠΈΡΡΠΈΠΈ 16 ΠΌΠ΅Ρ. ΠΠ²Π΅ ΠΏΠ°ΡΠΈΠ΅Π½ΡΠΊΠΈ ΡΠΎ IIB ΡΡΠ°Π΄ΠΈΠ΅ΠΉ Π² Π½Π°ΡΡΠΎΡΡΠ΅Π΅ Π²ΡΠ΅ΠΌΡ ΠΏΡΠΎΠ΄ΠΎΠ»ΠΆΠ°ΡΡ ΠΏΠΎΠ»ΡΡΠ°ΡΡ ΠΏΠ΅ΡΠ²ΠΈΡΠ½ΠΎΠ΅ Π»Π΅ΡΠ΅Π½ΠΈΠ΅.ΠΠ°ΠΊΠ»ΡΡΠ΅Π½ΠΈΠ΅. ΠΡΠ½ΠΎΠ²Π½Π°Ρ ΠΊΠ»ΠΈΠ½ΠΈΡΠ΅ΡΠΊΠ°Ρ ΠΏΡΠΎΠ±Π»Π΅ΠΌΠ° Π·Π°ΠΊΠ»ΡΡΠ°Π΅ΡΡΡ Π² ΡΠ΅Π΄ΠΊΠΎΠΉ Π²ΡΡΡΠ΅ΡΠ°Π΅ΠΌΠΎΡΡΠΈ Π΄Π°Π½Π½ΠΎΠ³ΠΎ Π³ΠΈΡΡΠΎΠ»ΠΎΠ³ΠΈΡΠ΅ΡΠΊΠΎΠ³ΠΎ ΠΏΠΎΠ΄ΡΠΈΠΏΠ° ΠΎΠΏΡΡ
ΠΎΠ»ΠΈ ΡΠ΅ΠΉΠΊΠΈ ΠΌΠ°ΡΠΊΠΈ. ΠΡΠ±ΠΎΡ ΡΠ°ΠΊΡΠΈΠΊΠΈ Π»Π΅ΡΠ΅Π½ΠΈΡ ΡΠ΅ΡΠ°Π΅ΡΡΡ ΠΌΡΠ»ΡΡΠΈΠ΄ΠΈΡΡΠΈΠΏΠ»ΠΈΠ½Π°ΡΠ½ΠΎ ΠΈ ΡΡΠ΅Π±ΡΠ΅Ρ Π΄Π°Π»ΡΠ½Π΅ΠΉΡΠΈΡ
ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΠΉ.