Soil Liquefaction Seismic Risk Analysis Based on Post 1979 Earthquake Observations in Montenegro

The scale and consequences of soil liquefaction during April 15, 1979 Montenegro earthquake rose a problem of explanation of this phenomena and assessment of the ground behaviour during future earthquakes. The analysis, the details and results presented in this paper is divided into two parts: The first part comprises soil liquefaction during Aprill5 1979 earthquake including the analysis of both geotechnical conditions and excitation potential inducing them. In order to realise the scale and the properties of the phenomenon, distribution of the locations with manifestations likely to have been induced by soil liquefaction, as observed on the ground surface and on civil engineering structures, has been given and described. To identify the presence of conditions inducing soil liquefaction the geotechnical soil properties for several typical locations have been analysed. Analysis of the characteristic ground surface horizontal acceleration records obtained by the earthquake from the aspect of their potential to cause liquefaction have been also carried out. To determine the liquefaction potential of the considered earthquake detailed analysis of typical geotechnical model of a site have been performed. In the second part is presented the seismic risk analysis background for soil liquefaction aimed at explanation of the essential problems concerning the evaluation of geotechnical media comprising of loose sand under the effect of future earthquakes. At the same time, the complexity of the problems which have to be dealt with during the seismic risk investigations has been pointed out concerning the necessity of investigation in this sense. It is necessary to make some assumptions and simplifications for solving sane of these problems. Applying the results of the analysis from the first part as well as the assumptions and simplifications, an assesment of the seismic risk for soil liquefaction analysed in details in the first part applying one of the possible methodologies, has been carried out

Pair-trading Method based Corporation Portfolio Management

Статья является введением в использование метода наименьших квадратов для исключения общих фундаментальный зависимостей из смежных инструментов. Рассматриваются такие аспекты, как применение метода наименьших квадратов, расчет коэффициентов, анализ результатов и получение выводов о динамике уникальных факторов рассматриваемых инструментов.The article presents an introduction into the usage of ordinary least squares method for connected instruments common fundamental dependencies removal. The article deals with such aspects as applying ordinary least squares method, coefficient computations, results analysis and receiving conclusion of given instruments unique factors dynamics

Innovative Surgical Approaches That Improve Individual Outcomes in Advanced Breast Cancer

Valerii Luțenco,1,* Laura Rebegea,2,3,* Adrian Beznea,1,3 George Tocu,3,* Monica Moraru,3 Oana Mariana Mihailov,3,* Bogdan Mihnea Ciuntu,4,* Verginia Luțenco,5 Floris Cristian Stanculea,6 Raul Mihailov1,3,* 1Surgery I Clinic, Emergency Hospital “Sf. Ap. Andrei”, Galați, Romania; 2Oncology and Radiotherapy Clinic, Emergency Hospital “Sf. Ap. Andrei”, Galați, Romania; 3“Dunărea de Jos” University of Galati, Faculty of Medicine and Pharmacy, Galați, Romania; 4“Gr. T. Popa” University of Medicine and Pharmacy, Iasi, Romania; 5Clinical Children Emergency Hospital “Sf. Ioan”, Galați, Romania; 6“Carol Davila” University of Medicine and Pharmacy, Bucuresti, Romania*These authors contributed equally to this workCorrespondence: George Tocu; Oana Mariana Mihailov, “Dunarea de Jos” University of Galati, 47 Domneasca Street, Galați, 800008, Romania, Tel +40728249228 ; +40745250391, Email [email protected]; [email protected]: Breast cancer is the most common cause of cancer death in women and the second cause in the general population. The incidence has increased over time. Women in developing countries often present at an advanced stage where initial surgery is not feasible. Short disease-free intervals, the number of metastatic organs and liver metastasis were consistently associated with poor overall survival. Surgery is an integral part of the therapeutic plan for locally advanced breast cancer. The integration of surgical care into the management of patients with advanced cancer has changed substantially with the use of neoadjuvant chemotherapy. Also, more recently, neoadjuvant endocrine therapy and targeted therapies offer new opportunities to downsize the tumor burden and transform the role of surgery for this population from palliation to largely curative intent. Innovative surgical approach to the primary tumor in metastatic disease may provide survival benefits and local control in some patients. Similar to systemic therapy, surgical therapy for secondary dissemination should be considered in certain cases for improved individual outcomes. Advances in reconstructive techniques have improved the quality of life of these patients.Keywords: breast cancer, locally advanced, metastatic, individual outcomes, surger

Polarization tomography of a narrow-band biphoton field

Narrow-band orthogonally polarized collinear frequency-degenerate biphotons are generated in the process of the spontaneous parametric down-conversion of light in a nonlinear BBO crystal placed in an optical resonator. Quantum polarization tomography and polarization transformation of the generated biphoton states are performed. The results from our experiment agree well with theoretical calculations. © Allerton Press, Inc., 2011

Subungual squamous cell carcinoma leading to arm amputation

Although rare, subungual carcinoma is the most common malignant nail tumor. The symptomatology is not characteristic, being very similar to that of other nail and periungual diseases. For this reason, early diagnosis is usually established by performing a biopsy. With appropriate treatment, subungual carcinoma usually has a favorable prognosis. Metastatic cases are rarely encountered, but they usually have a poor therapeutic result. This article presents the case of a patient with subungual carcinoma (diagnosed by histopathological exam), initially treated by amputation of the distal and middle phalanges of the fourth finger. Two years after the operation, a recurrence in the epitrochlear nodes was diagnosed, for which epitrochlear lymphadenectomy and postoperative chemotherapy were performed. At 7 months, metastases were detected in the axillary nodes, which were treated with radiotherapy and chemotherapy. The appearance and development of the tumor at the elbow and the lower third of the arm led the patient to accept scapulohumeral disarticulation. The patient finally adapted to the physical infirmity, having a good general condition and an optimistic attitude

Superfluid to normal phase transition and extreme regularity of superdeformed bands

We derive the exact semiclassical expression for the second inertial parameter $\cal B$ for the superfluid and normal phases. Interpolation between these limiting values shows that the function ${\cal B}(I)$ changes sign at the spin $I_c$, which is critical for a rotational spectrum. The quantity $\cal B$ turns out to be a sensitive measure of the change in static pairing correlations. The superfluid-to-normal transition reveals itself in the specific variation of the ratio ${\cal B}/{\cal A}$ versus spin $I$ with the plateau characteristic of the normal phase. We find this dependence to be universal for normal deformed and superdeformed bands. The long plateau with a small value ${\cal B}/{\cal A}\sim A^{-8/3}$ explains the extreme regularity of superdeformed bands.Comment: 30 pages in LaTeX, 6 figures (PostScript). To be published in Yadernaya Fizika (Physics of Atomic Nuclei), special edition dedecated to the 90th birthday of Prof. I. I. Gurevit

Development of a single tube 640-plex genotyping method for detection of nucleic acid variations on microarrays

Detection of DNA sequence variation is critical to biomedical applications, including disease genetic identification, diagnosis and treatment, drug discovery and forensic analysis. Here, we describe an arrayed primer extension-based genotyping method (APEX-2) that allows multiplex (640-plex) DNA amplification and detection of single nucleotide polymorphisms (SNPs) and mutations on microarrays via four-color single-base primer extension. The founding principle of APEX-2 multiplex PCR requires two oligonucleotides per SNP/mutation to generate amplicons containing the position of interest. The same oligonucleotides are then subsequently used as immobilized single-base extension primers on a microarray. The method described here is ideal for SNP or mutation detection analysis, molecular diagnostics and forensic analysis. This robust genetic test has minimal requirements: two primers, two spots on the microarray and a low cost four-color detection system for the targeted site; and provides an advantageous alternative to high-density platforms and low-density detection systems

Cyclotron resonance in HgTe/CdTe-based heterostructures in high magnetic fields

Cyclotron resonance study of HgTe/CdTe-based quantum wells with both inverted and normal band structures in quantizing magnetic fields was performed. In semimetallic HgTe quantum wells with inverted band structure, a hole cyclotron resonance line was observed for the first time. In the samples with normal band structure, interband transitions were observed with wide line width due to quantum well width fluctuations. In all samples, impurity-related magnetoabsorption lines were revealed. The obtained results were interpreted within the Kane 8·8 model, the valence band offset of CdTe and HgTe, and the Kane parameter E(P) being adjusted