Flow-chart of the study.

<p>Flow-chart of the study.</p

AUROC curve analysis for R_D1L, including the overall cohort (0.79; p<0.001), the estimation cohort (0.77; p<0.001) and the validation cohort (0.71; p<0.001)

<p>AUROC curve analysis for R_D1L, including the overall cohort (0.79; p<0.001), the estimation cohort (0.77; p<0.001) and the validation cohort (0.71; p<0.001)</p

Comparison of baseline characteristics; mono-infected <i>vs</i>. co-infected patients.

<p>Comparison of baseline characteristics; mono-infected <i>vs</i>. co-infected patients.</p

Variables associated with RVR in multivariate analysis of the estimation cohort.

<p>Variables associated with RVR in multivariate analysis of the estimation cohort.</p

The decision tree based on sensitivity of the proposed prognostic tool to predict RVR and D1L.

<p>The decision tree based on sensitivity of the proposed prognostic tool to predict RVR and D1L.</p

Rapid virological response in patients segregated with respect to mono-infection or co-infection

<p>Rapid virological response in patients segregated with respect to mono-infection or co-infection</p

AUROC curve analysis for R_RVR, including the overall cohort (0.82; p<0.001), the estimation cohort (0.83; p<0.001) and the validation cohort (0.82; p<0.001)

<p>AUROC curve analysis for R_RVR, including the overall cohort (0.82; p<0.001), the estimation cohort (0.83; p<0.001) and the validation cohort (0.82; p<0.001)</p