Conditions affecting the capacity for cardioprotection by preconditioning (IPreC) obtained by substracting the LDH values of the I/R alone group from the IPreC group for each individual patients and then compared with the mean value of the remainder study population.

<p>Conditions affecting the capacity for cardioprotection by preconditioning (IPreC) obtained by substracting the LDH values of the I/R alone group from the IPreC group for each individual patients and then compared with the mean value of the remainder study population.</p

Lactate dehydrogenase (LDH) leakage (A1) and 3-(4,5-dimethyl thiazol-2-yl)-2,5diphenyl tetrazolium bromide (MTT) reduction (B1) and the correlation between IPreC and I/R alone for LDH release (A2) and MTT reduction (B2) of human myocardium muscles (n = 300 per group) subjected to 250 min of aerobic condictions (AC), 90 min of ischemia followed by 120 min of reoxygenation (I/R alone), or ischemic preconditioning (IPreC) induced by 5 min of ischemia followed by 5 min of reoxygenation prior to the 90 min of ischemia.

<p>The mean values are shown. *<i>p</i> < 0.05 vs AC group and †<i>p</i> < 0.05 vs I/R alone group.</p

Indexes of basal redox status in human right atrial tissue (n = 90) from patients with conditions that affect myocardial susceptibilility to I/R-induced injury and the capacity for IPreC-mediated protection.

<p>Indexes of basal redox status in human right atrial tissue (n = 90) from patients with conditions that affect myocardial susceptibilility to I/R-induced injury and the capacity for IPreC-mediated protection.</p

Conditions affecting the susceptibility to ischemia/reoxygenation (I/R)-induced injury obtained by substracting the LDH values of the AC group from the I/R alone group for each individual patients and then compared with the mean value of the remainder study population.

<p>Conditions affecting the susceptibility to ischemia/reoxygenation (I/R)-induced injury obtained by substracting the LDH values of the AC group from the I/R alone group for each individual patients and then compared with the mean value of the remainder study population.</p

Experimental protocol.

<p>Tissues in all groups were equilibrated for 30–40 min at 37°C in aerobic conditions. Muscle tissues were either maintained under aerobic conditions (AC) for the entire experimental period or subjected to 90 min of ischemia followed by 120 min of ischemia/reoxygenation (I/R alone) or preconditioned (IPreC) with 5 min of ischemia and 5 min of reoxygenation.</p

Demographic data of study patients.

<p>Demographic data of study patients.</p