5 research outputs found
Association between liver biochemical test parameters and serum glucose.
<p>Tertiles of plasma LnALT, LnAST, LnGGT and serum LnTriglyceride (TG) (mmol/L) in association with nonfasting serum levels (mmol/L) of glucose. Asterisks (*p<0.05, **p<0.01, ***p<0.001) represents significant difference between groups using linear regression analysis, correcting for relation to sibling relationship, age, gender, smoking, alcohol use in g/day, and number of hepatotoxic medication. NS: not significant.</p
Nonfasting liver enzymes and triglycerides in offspring of long-lived siblings and control subjects.
<p>Results are from linear mixed models, correcting for age, gender, and correlation of sibling relationship (model 1) and additionally for smoking, body mass index, alcohol use in g/day and number of hepatotoxic medications (model 2). Models were fitted for natural log-transformed values of alanine transaminase (ALT), aspartate transaminase (AST), gamma-glutamyltransferase (GGT), and LnTriglycerides. Geometric means (95% confidence interval) are reported for transformed variables.</p
Computed tomography markers of liver steatosis in offspring of long-lived siblings and control subjects.
<p>Results are from linear mixed model and logistics regression analysis, correcting for age and gender (model 1) and additionally for smoking, body mass index, alcohol use in g/day, and number of hepatotoxic medications (model 2).</p>†<p>LS ratio were available in 131 offspring and 116 controls.</p><p>NAFLD: moderate-to-severe non-alcoholic fatty liver disease, L/S ratio: liver/spleen ratio, 95% CI: 95% confidence interval, HU: hounsfield units.</p
Additional file 1: of Association between changes in brain microstructure and cognition in older subjects at increased risk for vascular disease
List of the individual ethics committees that gave approval for the Prospective Study of Pravastatin in the Elderly at Risk study. (DOCX 13 kb
Subject demographics.
<p>Values are means (SE, standard error or 95% CI, confidence interval) or numbers (%). P values are from student’s t-test (<sup>†</sup>), Pearson chi-square test (<sup>‡</sup>), and from linear mixed model analysis, correcting for age, gender, BMI, and correlation of sibling relationship (<sup>a</sup>). Models were fitted for natural log-transformed values for insulin. For transformed variables, data are presented as geometric means with 95% confidence intervals.</p><p>Age: age at serum screening, Hypertension: systolic blood pressure ≥130 mmHg and/or diastolic pressure ≥85 mmHg, or administration of antihypertensive medication, COPD: chronic obstructive pulmonary disease, Insulin: nonfasting serum insulin levels, Glucose: nonfasting serum glucose levels.</p