The Grizzly, November 4, 1988

Continued Controversy Plagues Campus • Division III\u27s Founding Athletics • Curriculum IDEAS Fire Faculty • Drive to be Closed • Letter: Guilty Till Proven Innocent: Democracy at Ursinus College • Conference a Great Success • Bear Pack Braces for Title Run • Seniors are Class of Hockey • Career Day to be Sponsored for Campus • Security Moves to Reimert • French Presents Finzihttps://digitalcommons.ursinus.edu/grizzlynews/1222/thumbnail.jp

The Grizzly, October 14, 1988

Task Force Committee Trims Curriculum • Gender, Class and Race Addressed at Conference • Awareness Week on the Wagon • Letters: Some Sobering Thoughts for Students; Interdepartmental Cooperation Stressed • And the Band Played On... • A Voice of My Own to Air • Wellness Week Results • Rice Cooks Up Recipe for Art • Bears Take Homecoming Thriller in Final :33 • Soccer Kicks Into Winning Gear • X-Country Runs \u27Round Alumni • Hockey Unpredictablehttps://digitalcommons.ursinus.edu/grizzlynews/1220/thumbnail.jp

The Grizzly, November 11, 1988

Bush Takes Election: Republicans Win Four More • Students Voice Concerns: Richter and Kane Listen • Letter: Beam The Grizzly Up, Billy • Finzi\u27s French\u27s Forte • College\u27s Music Program Reviewed • The Pack is Back with 5th MAC Title • Ladies Take Seventh • \u27Mers Open Season • Soccer Booted in ECAC • The Grizzly Presents our Champion Team • Red and Gold Days: A Big Hit • Presenting Women\u27s Achievementhttps://digitalcommons.ursinus.edu/grizzlynews/1223/thumbnail.jp

The Grizzly, November 18, 1988

Booze Ban - No Bomb - But No New Booze News • Hess Awarded Honorary Chair • Talent Show Dazzles Ursinus Community • Letters: Alumnus Voices Drug Concerns; Stuff it in Your Socks, Mr. Bill • Escape with Chiapparone • Meehan, U.C. Spoil Dickinson\u27s Party • Pack Takes 3rd; O\u27Donohue Makes Nationals • Matters Fare Well at LaSalle Tourney • Circle Up with Circle K • Hoopsters Open with Cautious Optimismhttps://digitalcommons.ursinus.edu/grizzlynews/1224/thumbnail.jp

Proprioceptive Coupling within Motor Neurons Drives C. Elegans Forward Locomotion

Locomotion requires coordinated motor activity throughout an animal’s body. In both vertebrates and invertebrates, chains of coupled central pattern generators (CPGs) are commonly evoked to explain local rhythmic behaviors. In C. elegans, we report that proprioception within the motor circuit is responsible for propagating and coordinating rhythmic undulatory waves from head to tail during forward movement. Proprioceptive coupling between adjacent body regions transduces rhythmic movement initiated near the head into bending waves driven along the body by a chain of reflexes. Using optogenetics and calcium imaging to manipulate and monitor motor circuit activity of moving C. elegans held in microfluidic devices, we found that the B-type cholinergic motor neurons transduce the proprioceptive signal. In C. elegans, a sensorimotor feedback loop operating within a specific type of motor neuron both drives and organizes body movement.Chemistry and Chemical BiologyPhysic

The Grizzly, April 7, 1989

History in Making: Middle States Arrive Sunday • APO Holds Local Fraternity Chapter Conference • Letters: Normal Pledging O.K.; Booby not Prize • DeLeon Woos Wismer • Hundreds to Storm Campus • Friday\u27s Fun, But Not Food Fantasy • Men\u27s Lacrosse Begins with a Bang! • Bowers Leads U.C. to Win • Driscoll, Ursinus Set High Goals • Tough Schedule to Benefit U.C. Lax • Two Week Pledging Proposed by Subcommittee on Greeks • Boston: Seats Going Fast • It\u27s Tenure Time Once Again! • U.S.G.A Update • Cinders to Rock U.C. • U.S.G.A. Needs You! • Rumors a Real Bomb • Take a Bite! • College Displays Crime Statshttps://digitalcommons.ursinus.edu/grizzlynews/1234/thumbnail.jp

Prevalence of Post-liver Transplant Complications and NASH-Related Cirrhosis in Postmenopausal Women

INTRODUCTION AND OBJECTIVES: Compared to premenopausal women, postmenopausal women are at greater risk of developing NAFLD and NASH, two common indications for liver transplantation (LT). We aim to determine the prevalence of NASH-related cirrhosis in postmenopausal women from a cohort of LT patients and investigate their post-LT complications. MATERIALS AND METHODS: Chart review of 1200 LT patients from 2002-2020 was performed. Postmenopausal women were defined as women over 51 and compared to a control group of men over 51. Prevalence of LT indications was determined. Subgroup analysis assessed cardiovascular disease risk. BMI and ASCVD risk scores were calculated at the time of LT and after 1 year. RESULTS: 510 patients met the inclusion criteria: 189 (37.1%) women and 321 (62.9%) men. The most common indication was NASH for women (26.5%, p CONCLUSIONS: Postmenopausal women were significantly more likely to have NASH as an indication for LT than men. Postmenopausal women had greater weight gain and more noncardiac complications than men. Women did not have increased cardiovascular outcomes, ASCVD risk, or mortality. Diet education and weight control in postmenopausal women with existing risk factors for NASH should be encouraged to modulate health outcomes

The Grizzly, February 24, 1989

Ursinus Finds and Dumps Its Own Dump • Depression Treatable • GPA Lowered for Frat Pledges • Letter: Mannherz Assaults Grizzly • Myrin Library Meeting Future • Photos Don\u27t Show All, More to Dump Than Meets the Eye • Ursinus Awaits ECAC Bid • Matters Set School Record • McMullin Keys U.C. Track • U.C.: Up, Then Down • Ursinus Women: The Stuff of Champions • Cinders Smoking • Meisters: Ohio or Bust! • Richter Doesn\u27t Trash Klee • Wismer Deceiving Diners • DeCatur Nips Nippon • Yanks and Frogs Alike • Airband Tonight • Graduation 1989 Coming Together • Peruvian Paradisehttps://digitalcommons.ursinus.edu/grizzlynews/1230/thumbnail.jp

Mongooses (\u3ci\u3eUrva auropunctata\u3c/i\u3e) as reservoir hosts of leptospira species in the United States Virgin Islands, 2019–2020

During 2019–2020, the Virgin Islands Department of Health investigated potential animal reservoirs of Leptospira spp., the bacteria that cause leptospirosis. In this cross-sectional study, we investigated Leptospira spp. exposure and carriage in the small Indian mongoose (Urva auropunctata, syn: Herpestes auropunctatus), an invasive animal species. This study was conducted across the three main islands of the U.S. Virgin Islands (USVI), which are St. Croix, St. Thomas, and St. John. We used the microscopic agglutination test (MAT), fluorescent antibody test (FAT), real-time polymerase chain reaction (lipl32 rt-PCR), and bacterial culture to evaluate serum and kidney specimens and compared the sensitivity, specificity, positive predictive value, and negative predictive value of these laboratory meth-ods. Mongooses (n = 274) were live-trapped at 31 field sites in ten regions across USVI and humanely euthanized for Leptospira spp. testing. Bacterial isolates were sequenced and evaluated for species and phylogenetic analysis using the ppk gene. Anti-Leptospira spp. antibodies were detected in 34% (87/256) of mongooses. Reactions were observed with the following serogroups: Sejroe, Icterohaemorrhagiae, Pyrogenes, Mini, Cynopteri, Australis, Hebdomadis, Autumnalis, Mankarso, Pomona, and Ballum. Of the kidney specimens exam-ined, 5.8% (16/270) were FAT-positive, 10% (27/274) were culture-positive, and 12.4% (34/ 274) were positive by rt-PCR. Of the Leptospira spp. isolated from mongooses, 25 were L. borgpetersenii, one was L. interrogans, and one was L. kirschneri. Positive predictive values of FAT and rt-PCR testing for predicting successful isolation of Leptospira by culture were 88% and 65%, respectively. The isolation and identification of Leptospira spp. in mongooses highlights the potential role of mongooses as a wildlife reservoir of leptospirosis; mongooses could be a source of Leptospira spp. infections for other wildlife, domestic animals, and humans