A Community-Based Obesity Prevention Program Decreased the Body Mass Index of University-Affiliated Participants

Obesity is a national health concern and the focus of many health promotion programs. The purpose of this study was to evaluate the behavioral impact of a 12-week obesity prevention program on a university campus. Participants were provided questionnaires with weights, heights, and body mass indices (BMIs) determined at the pre-phase weigh-in and post-phase weigh-out. At the weigh-in, participants received pedometers and information about upcoming educational sessions to assist them with reaching their health behavior goals. A total of 247 (38.2% of 646) individuals (79.4% women) completed the program. A mean weight loss of 1.8 kg caused a decrease in BMI from 29.3 at weigh-in to 28.7 at weigh-out (p = .002). Pre- and post-questionnaires indicated increases (p \u3c 0.001) in physical activity; using pedometers; and intakes of fruits, vegetables, and water at the end of the program. The 6-month follow-up questionnaire (33.2% response rate) indicated healthy habits were being maintained for fruit and vegetable consumption. Further intervention development to incorporate innovative strategies for promoting healthy behaviors among students and employees on university campuses could help decrease the prevalence of obesity

Bioluminescence Imaging of Angiogenesis in a Murine Orthotopic Pancreatic Cancer Model

Angiogenesis is essential for physiological processes as well as for carcinogenesis. New approaches to cancer therapy include targeting angiogenesis. One target is VEGF-A and its receptor VEGFR2. In this study, we sought to investigate pancreatic cancer angiogenesis in a genetically modified VEGFR2-luc-KI mouse

Climatology of the Combined ASTER MODIS Emissivity over Land (CAMEL) Version 2

The Combined ASTER (Advanced Spaceborne Thermal Emission and Reflection Radiometer) MODIS (Moderate Resolution Imaging Spectroradiometer) Emissivity over Land (CAMEL) Version 2 (V002) has been available since March 2019 from the NASA LP DAAC (Land Processes Distributed Active Archive Center) and provides global, monthly infrared land surface emissivity and uncertainty at 0.05 degrees (~5 km) resolution. A climatology of the CAMEL V002 product is now available at the same spatial, temporal, and spectral resolution, covering the CAMEL record from 2000 to 2016. Characterization of the climatology over case sites and IGBP (International Geosphere-Biosphere Programme) land cover categories shows the climatology is a stable representation of the monthly CAMEL emissivity. Time series of the monthly CAMEL V002 product show realistic seasonal changes but also reveal subtle artifacts known to be from calibration and processing errors in the MODIS MxD11 emissivity. The use of the CAMEL V002 climatology mitigates many of these time dependent errors by providing an emissivity estimate which represents the complete 16-year record. The CAMEL V002 climatology’s integration into RTTOV (Radiative Transfer for TOVS) v12 is demonstrated through the simulation of IASI (Infrared Atmospheric Sounding Interferometer) radiances. Improved stability in CAMEL Version 3 is expected in the future with the incorporation of the new MxD21 and VIIRS VNP21 emissivity products in MODIS Collection 6.1

Simulation of CrIS Radiances Accounting for Realistic Properties of the Instrument Responsivity That Result in Spectral Ringing Features

This paper provides a procedure for the simulation of radiances from the U. S. National Oceanic and Atmospheric Administration (NOAA) Cross-track Infrared Sounder (CrIS) Fourier Transform Spectrometer to include spectral ringing effects caused by the finite-band, non-flat instrument spectral response to incident radiation. A simulation using a line-by-line radiative transfer model is performed to illustrate the magnitude of the effect and to indicate which spectral channels are likely to be impacted. Comparisons with CrIS observations are made to show that for most channels this effect is negligibly small compared to errors in the radiative transfer calculations but for the longwave edge of the CrIS longwave band and a few other regions, the brightness temperature ringing is significant. While the ringing artifact described in this paper may appear to be removed when Hamming apodization is applied, as is done for the assimilation of CrIS data into Numerical Weather Prediction (NWP) models, it is still present, and its influence reappears if the spectral correlation induced by apodization is properly handled to preserve the information content that derives from high spectral resolution. Inclusion of the instrument responsivity in calculated spectra to properly mimic the observed spectra as defined here eliminates artifacts from this type of ringing. Users of CrIS radiances should consider whether this effect is important for their application

Far Infrared Emissivity Estimates of Various Sample Types from the Ground-Based Absolute Radiance Interferometer

This data is published to be companion to the peer-reviewed paper submitted to Earth and Space Science named “Ground-Based Far Infrared Emissivity Measurements Using the Absolute Radiance Interferometer”. This paper describes the data collection process and emissivity derivation technique in detail. The data included here are the single channel and microwindow emissivities which have been derived from the PC-noise-filtered ARI radiance measurements from the 2022 measurement campaign

Detection of the Bacillus anthracis gyrA Gene by Using a Minor Groove Binder Probe

Identification of chromosomal markers for rapid detection of Bacillus anthracis is difficult because significant chromosomal homology exists among B. anthracis, Bacillus cereus, and Bacillus thuringiensis. We evaluated the bacterial gyrA gene as a potential chromosomal marker for B. anthracis. A real-time PCR assay was developed for the detection of B. anthracis. After analysis of the unique nucleotide sequence of the B. anthracis gyrA gene, a fluorescent 3′ minor groove binding probe was tested with 171 organisms from 29 genera of bacteria, including 102 Bacillus strains. The assay was found to be specific for all 43 strains of B. anthracis tested. In addition, a test panel of 105 samples was analyzed to evaluate the potential diagnostic capability of the assay. The assay showed 100% specificity, demonstrating the usefulness of the gyrA gene as a specific chromosomal marker for B. anthracis

Lineage tracing and analog recording in mammalian cells by single-site DNA writing

Studying cellular and developmental processes in complex multicellular organisms can require the non-destructive observation of thousands to billions of cells deep within an animal. DNA recorders address the staggering difficulty of this task by converting transient cellular experiences into mutations at defined genomic sites that can be sequenced later in high throughput. However, existing recorders act primarily by erasing DNA. This is problematic because, in the limit of progressive erasure, no record remains. We present a DNA recorder called CHYRON (Cell History Recording by Ordered Insertion) that acts primarily by writing new DNA through the repeated insertion of random nucleotides at a single locus in temporal order. To achieve in vivo DNA writing, CHYRON combines Cas9, a homing guide RNA and the template-independent DNA polymerase terminal deoxynucleotidyl transferase. We successfully applied CHYRON as an evolving lineage tracer and as a recorder of user-selected cellular stimuli

Educational ICT and Stimulating Heresies BERA New Technologies Special Interest Group, Symposium: British Education

The growth in interest and the application of Information and Communications Technology (ICT) in education over the last five years has been rapid, leading to the massive investment programmes including the creation of the 'National Grid for Learning' and New Opportunities Fund ICT training for teachers and librarians. However it could be said that there has been relatively little theoretical or conceptual development in these areas over the same period. This paper describes a small-scale collaborative research project designed to stimulate some new lines of thinking and critical discussion in the domain of educational ICT. A Delphi type methodology was used to identify the 'top 10 heresies ' with regard to the 'orthodoxy ' of ICT and education- beliefs, values, practice and attitudes, amongst the members of two Internet mail-list communities each with a focus on educational ICT. The paper then goes on to explore the findings and how they can be/have been used to simulate new ideas and critical discussion in this increasingly important area of education. Key Words: ICT, ideas, heresies Acknowledgements: This paper reports on a collaborative project which was only possible due to the hard work and perseverance over a six month period of my fellow participants