3,267 research outputs found
Information criterion for the categorization quality evaluation
The paper considers the possibility of using the variation of information function as a quality criterion for categorizing a collection of documents. The performance of the variation of information function is being examined subject to the number of categories and the sample volume of the test document collection
A mesoscopic model for microscale hydrodynamics and interfacial phenomena: Slip, films, and contact angle hysteresis
We present a model based on the lattice Boltzmann equation that is suitable
for the simulation of dynamic wetting. The model is capable of exhibiting
fundamental interfacial phenomena such as weak adsorption of fluid on the solid
substrate and the presence of a thin surface film within which a disjoining
pressure acts. Dynamics in this surface film, tightly coupled with
hydrodynamics in the fluid bulk, determine macroscopic properties of primary
interest: the hydrodynamic slip; the equilibrium contact angle; and the static
and dynamic hysteresis of the contact angles. The pseudo- potentials employed
for fluid-solid interactions are composed of a repulsive core and an attractive
tail that can be independently adjusted. This enables effective modification of
the functional form of the disjoining pressure so that one can vary the static
and dynamic hysteresis on surfaces that exhibit the same equilibrium contact
angle. The modeled solid-fluid interface is diffuse, represented by a wall
probability function which ultimately controls the momentum exchange between
solid and fluid phases. This approach allows us to effectively vary the slip
length for a given wettability (i.e. the static contact angle) of the solid
substrate
A 12-fold ths interpenetrated network utilizing a glycine-based pseudopeptidic ligand
We report the synthesis and characterization of a 3D Cu(II) coordination polymer, [Cu3(L1)2(H2O)8]·8H2O (1), with the use of a glycine-based tripodal pseudopeptidic ligand (H3L1 = N,N’,N’’-tris(carboxymethyl)-1,3,5-benzenetricarboxamide or trimesoyl-tris-glycine). This compound presents the first example of a 12-fold interpenetrated ths net. We attempt to justify the unique topology of 1 through a systematic comparison of the synthetic parameters in all reported structures with H3L1 and similar tripodal pseudopeptidic ligands. We additionally explore the catalytic potential of 1 in the A3 coupling reaction for the synthesis of propargylamines. The compound acts as a very good heterogeneous catalyst with yields up to 99% and loadings as low as 3 mol%
The Use of Alginate Hydrogels for the Culture of Mesenchymal Stem Cells (MSCs): In Vitro and In Vivo Paradigms
Alginate hydrogels have been widely used in stem cell cultures due to their biocompatibility, malleable nature, high water content, enhanced mass transport properties, and their functionalization with bioactive molecules providing cues that modulate cell proliferation and differentiation. Mesenchymal stem cells (MSCs) are extensively utilized in clinical cellular therapies because of their differentiation efficiency, their immunosuppressive properties, and them not being tumorigenic when implanted in vivo. MSCs are isolated from numerous fetal and adult tissues, suitable for both autologous and allogeneic applications. Consequently, alginate hydrogels/MSCs have been applied in vivo for the treatment of a wide variety of musculoskeletal, cardiac, neural, and endocrine disorders. This chapter will review the use of alginate hydrogels (physical properties and functionalization) for MSC culture in vitro (various culture systems) and the application of alginate/MSC implants (animal models and human applications) for cellular therapy purposes in vivo
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