Multivariate analysis RP11-570L13.

<p>Cox regression hazard model was used for multivariate analysis to assess the prognostic value of aberrations.</p><p>HR, hazard ratio; CI, confidence interval; UICC, Union for International Cancer Control.</p><p>Multivariate analysis RP11-570L13.</p

Allelotyping results.

<p>AI: allelic imbalance; NI: non-informative;</p><p>values in parenthesis are percentages.</p><p>Allelotyping results.</p

Loss of 4q21.23 in DTCs and tumor tissue of a NSCLC patient.

<p>Bone-marrow cells of the patient were immunocytochemically stained against cytokeratin using the APAAP method. A positive DTC (red) and a negative leukocyte (brown) are shown. <b>B</b>: Bone-marrow cells of the patient were stained fluorescently against cytokeratin (red signal) followed by FISH analysis in <b>C</b>) with RP11-1053C2 probe and Cen3 probe (RP11-1053C2 probe: 1 green signal; Cen3 probe: 3 spectrum orange signals; nuclear staining in DAPI). Cen7 probe (Cen7 probe: spectrum aqua displayed in the pseudo-color magenta) was in addition used for FISH analysis on <b>D</b>) primary tumor (2–5 orange signals/cell, 2–4 magenta signals/cell and 0–2 green signals/cell) and <b>E</b>) tumor relapse FFPE material (3–6 orange, 4–5 magenta and 1–3 green signals/cell).</p