Produktivní kultura vyučování a učení v didaktických kazuistikách

Title in English: Productive culture of teaching and learning in didactic case studies The book introduces the issue of productive culture of teaching and learning in broader didactical context. In the first part of the book, three areas of productive culture of teaching and learning are as theoretical framework presented: 1. clarity, structure, coherence, 2. cognitive activation, instrumentalization, semantization, 3. Supportive learning environment. The second part of the book presents 17 didactic case studies that have been developed by teams that consisted of researchers and teachers from schools. The aim of didactic case studies is to highlight key areas of productive culture of teaching and learning

Role of Long-Acting Injectable Second-Generation Antipsychotics in the Treatment of First-Episode Schizophrenia: A Clinical Perspective

Approximately 80% of patients with the first-episode schizophrenia reach symptomatic remission after antipsychotic therapy. However, within two years most of them relapse, mainly due to low levels of insight into the illness and nonadherence to their oral medication. Therefore, although the formal data available is limited, many experts recommend prescribing long-acting injectable second-generation antipsychotics (mostly risperidone or alternatively paliperidone) in the early stages of schizophrenia, particularly in patients who have benefited from the original oral molecule in the past and agree to receive long-term injectable treatment. Early application of long-acting injectable second-generation antipsychotics can significantly reduce the risk of relapse in the future and thus improve not only the social and working potential of patients with schizophrenia but also their quality of life

Selected neuroendocrine factors as potential molecular biomarkers of early non-affective psychosis course in relation to treatment outcome: A pilot study

The aim of this pilot study was to find whether the dysregulation of neuroendocrine biomarker signaling pathways in the first episode of non-affective psychosis is a predictive factor of treatment outcome. Patients with the first episode of non-affective psychosis (N = 29) were examined at admission, at discharge, and at follow-up (N = 23). The biomarkers included serum aldosterone, cortisol, free thyroxine, thyroid stimulating hormone, and prolactin. We revealed lower baseline aldosterone and higher baseline cortisol concentrations in patients with very good outcome compared to those with good outcome after one year. We failed to reveal any significant association between treatment outcome and neurohumoral biomarkers in the whole sample at 1-year follow-up. However, baseline aldosterone concentrations negatively correlated with total PANSS scores at the discharge. Lower baseline aldosterone and higher baseline cortisol concentrations have the potential to predict a more favorable outcome for patients with the first episode of psychosis

Oborové didaktiky: vývoj - stav - perspektivy

Obsah konference reflektoval právě vycházející monografii Oborové didaktiky: vývoj - stav - perspektivy. Cílem konference bylo přiblížit stěžejní problémy českého školství na pozadí oborových didaktik. K jednotlivým tématům se vyjádřili editoři, autoři, ale i recenzenti monografie