The analysis of cadmium and its oxide by atomic-emission and massspectrometry with inductive coupled plasma

In present work, the multielemental methods for the cadmium and its oxide analysis by atomicemission and mass-spectrometry with inductively coupled plasma (AES-ICP and MS-ICP) have been proposed. The influence of the matrix concentration and the power supplied to the plasma on the analytic signals of the impurities has been studied, analytical lines and isotopes of the determined elements have been chosen. We have made the accuracy estimation of the developed techniques, the ICP-AES technique allows to determine 41 analytes with detection limits in the range from n•10{-7} to n•10{-4} % wt, ICP-MS technique allows to determine 58 elements with detection limits on the level n •10{-8}-n•10{-3} % wt Введение. Кадмий высокой чистоты является прекурсором

Early functional results after Hemiarthroplasty for femoral neck fracture: a randomized comparison between a minimal invasive and a conventional approach

BACKGROUND: A minimal invasive approach for elective hip surgery has been implemented in our institution in the past. It is widely hypothesized that implanting artificial hips in a minimal invasive fashion decreases surgical trauma and is helpful in the rehabilitation process in elective hip surgery. Thereby geriatric patients requiring emergency hip surgery also could theoretically benefit from a procedure that involves less tissue trauma. METHODS: Sixty patients who sustained a fractured neck of femur were randomly assigned into two groups. In the minimal invasive arm, the so called “direct anterior approach” (DAA) was chosen, in the conventional arm the Watson-Jones-Approach was used for implantation of a bipolar hemi-arthroplasty. Primary outcome parameter was the mobility as measured by the four-item-Barthel index. Secondary outcome parameters included pain, haemoglobin-levels, complications, duration of surgery, administration of blood transfusion and external length of incision. Radiographs were evaluated. RESULTS: A statistically significant difference (p = 0,009) regarding the mobility as measured with the four-item Barthel index was found at the 5th postoperative day, favouring the DAA. Evaluation of the intensity of pain with a visual analogue scale (VAS) showed a statistically significant difference (p = 0,035) at day 16. No difference was evident in the comparison of radiographic results. CONCLUSIONS: Comparing two different approaches to the hip joint for the implantation of a bipolar hemi-arthroplasty after fractured neck of femur, it can be stated that mobilization status is improved for the DAA compared to the WJA when measured by the four-item Barthel index, there is less pain as measured using the VAS. There is no radiographic evidence that a minimal invasive technique leads to inferior implant position. Level of Evidence: Level II therapeutic study

A historical appraisal of the tropical forages collection conserved at CIAT

A report on the tropical forage germplasm collection conserved in the CIAT genebank is presented. Emphasis is firstly on the assembling of the collection during 1972−1993 through about 70 major and minor collecting missions in tropical America, Africa and Southeast Asia. Along with introductions from existing collections, currently some 1,600 accessions of 134 grass species and 21,000 accessions of 637 legume species are being maintained. Secondly, information on the utilization of the collection, with emphasis on cultivar development based on selection of accessions from the CIAT collection, is presented. Worldwide, a total of 44 grass and 34 legume cultivars derived from germplasm maintained at CIAT are reported. Information on germplasm distribution and knowledge sharing during the last four decades is also presented as well as a brief discussion on future needs

Разработка технологии изготовления детали «Седло»

Выпускная квалификационная работа включает в себя проектирование технологического процесса обработки детали "Седло" и содержит: анализ чертежа и технологичности детали; способ получения заготовки; расчет припусков на обработку; разработку технологического процесса, выбор и расчет режимов резания; размерный анализ технологического процесса.Final qualifying work includes the design of the technological process of processing details in the "Saddle" and contains: an analysis of drawing and technology details; method of harvesting; calculation of allowances for processing; the design process, the selection and calculation of cutting conditions; dimensional analysis process

Rates of severe complications in patients undergoing colorectal surgery for deep endometriosis-a retrospective multicenter observational study.

INTRODUCTION Surgical experience and hospital procedure volumes have been associated with the risk of severe complications in expert centers for endometriosis in France. However, little is known about other certified units in Central European countries. MATERIAL AND METHODS This retrospective observational study included 937 women who underwent surgery for colorectal endometriosis between January 2018 and January 2020 in 19 participating expert centers for endometriosis. All women underwent complete excision of colorectal endometriosis by rectal shaving, discoid or segmental resection. Postoperative severe complications were defined as grades III-IV of the Clavien-Dindo classification system including anastomotic leakage, fistula, pelvic abscess and hematoma. Surgical outcomes of centers performing less than 40 (group 1), 40-59 (group 2) and ≥60 procedures (group 3) over a period of 2 years were compared. RESULTS The overall complication rate of grade III and IV complications was 5.1% (48/937), with rates of anastomotic leakage, fistula formation, abscess and hemorrhage in segmental resection, discoid resection and rectal shaving, respectively, as follows: anastomotic leakage 3.6% (14/387), 1.4% (3/222), 0.6% (2/328); fistula formation 1.6% (6/387), 0.5% (1/222), 0.9%; (3/328); abscess 0.5% (2/387), 0% (0/222) and 0.6% (2/328); hemorrhage 2.1% (8/387), 0.9% (2/222) and 1.5% (5/328). Higher overall complication rates were observed for segmental resection (30/387, 7.8%) than for discoid (6/222, 2.7%, P = 0.015) or shaving procedures (12/328, 3.7%, P = 0.089). No significant correlation was observed between the number of procedures performed and overall complication rates (rSpearman  = -0.115; P = 0.639) with a high variability of complications in low-volume centers (group 1). However, an intergroup comparison revealed a significantly lower overall severe complication rate in group 3 than in group 2 (2.9% vs 6.9%; P = 0.017) without significant differences between other groups. CONCLUSIONS A high variability in complication rates does exist in centers with a low volume of activity. Major complications may decrease with an increase in the volume of activity but this effect cannot be generally applied to all institutions and settings

Donor regulatory T cells rapidly adapt to recipient tissues to control murine acute graft-versus-host disease

The adoptive transfer of regulatory T cells is a promising strategy to prevent graft-versus-host disease after allogeneic bone marrow transplantation. Here, we use a major histocompatibility complex-mismatched mouse model to follow the fate of in vitro expanded donor regulatory T cells upon migration to target organs. Employing comprehensive gene expression and repertoire profiling, we show that they retain their suppressive function and plasticity after transfer. Upon entering non-lymphoid tissues, donor regulatory T cells acquire organ-specific gene expression profiles resembling tissue-resident cells and activate hallmark suppressive and cytotoxic pathways, most evidently in the colon, when co-transplanted with graft-versus-host disease-inducing conventional T cells. Dominant T cell receptor clonotypes overlap between organs and across recipients and their relative abundance correlates with protection efficacy. Thus, this study reveals donor regulatory T cell selection and adaptation mechanisms in target organs and highlights protective features of Treg to guide the development of improved graft-versus-host disease prevention strategies