38 research outputs found

    The Victorian Newsletter (Fall 1986)

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    The Victorian Newsletter is sponsored for the Victorian Group of Modern Language Association by the Western Kentucky University and is published twice annually.Disraeli and Carlyle's "Aristocracy of Talent": The Role of Millbank in Coningsby Reconsidered / Nils Clausson -- The Reader as Whoremonger: A Phenomenological Approach to Rossetti's "Jenny" / Michael Cohen -- Letters and Novels "One Woman Wrote to Another": George Eliot's Responses to Elizabeth Gaskell / Robyn R. Warhol -- J. E. Millais' Bubbles: A Work of Art in the Age of Mechanical Reproduction / William Sharpe -- The Ordeal of Richard Feverel: Bildungsroman or anti-Bildungsroman? / Nikki Lee Manos -- Christianity, Spiritualism, and the Fourth Dimension in Late Victorian England / Rosemary Jann -- Great Burke and Poor Boswell: Carlyle and the Historian's Task / Elizabeth Wheeler -- Coming in Victorian Newsletter -- Books Receive

    Ultrastructural distinctions between adult pleomorphic rhabdomyosarcomas, pleomorphic liposarcomas, and pleomorphic malignant fibrous histiocytomas

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    The ultrastructural features of five pleomorphic rhabdomyosarcomas, five high-grade malignant fibrous histiocytomas, and five pleomorphic liposarcomas were studied. Electron microscopy was found to be consistently useful in distinguishing between these tumors. The rhabdomyosarcomas showed thick and thin filaments in complexes and consistently contained glycogen. The malignant fibrous histiocytomas had numerous lysosomes, often in cells with ruffled borders, and contained cells showing myofibroblastic differentiation. The liposarcomas showed abundant and coalescing lipid droplets, sparse stroma with condensation of amorphous granular materials surrounding plasma membranes, and prominent vascularity. Fourteen of the 15 tumors could be identified on the basis of ultrastructure; thus, electron microscopic examination is an important diagnostic tool for pleomorphic tumors. © 1984 W. B. Saunders Co

    Dead on the Vine: Living and Conceptual Art and Vara

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    Utility of CK7 and CK20 in the Immunohistochemical Detection of Simultaneous Colon and Breast Carcinoma in a Pleural Effusion: a case report and supporting survey of archival material.

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    We present a case of synchronous breast and colon carcinoma in a pleural effusion, to our knowledge the first such reported case in the English-language literature. The patient was a 55-yr-old white female with known metastatic breast and colon carcinoma who developed a malignant pleural effusion which demonstrated two strikingly different populations of malignant cells by immunohistochemical study of cell block material. One cell population demonstrated a cytokeratin (CK)7+/CK20-/ER+ phenotype, while the other demonstrated a CK7-/CK20+/ER- phenotype, consistent with breast and colon origin, respectively. An immunohistochemical survey of archival breast and colon primary and metastatic carcinomas confirmed the established CK7+/CK20- phenotype of breast and CK7-/CK20+ phenotype of colon primary carcinomas, and the maintenance of this phenotype in metastases thereof. A survey of benign and malignant mesothelial lesions confirmed the absence of staining for estrogen receptor, but showed 6/10 cases weakly positive for CK20, which has not been described in other published series. This unusual case graphically illustrates the utility of cytokeratin subset immunohistochemistry in effusion cytology
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