5 research outputs found
Radioiodination via isotope exchange in pivalic acid
A variety of benzoic and aryl aliphatic mono and polyiodinated acids and esters (sterol, triglyceride) were radioiodinated in 55-99% radiochemical yield by isotope exchange with Na 125I in a melt of pivalic acid. In general, the reaction was complete in 1 h at 155[deg]C with little or no substrate decompostion. High specific activity studies afforded 125I-labeled iopanoic acid with a specific activity of over 700 Ci/mmol.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/26445/1/0000533.pd
Synthesis of New Transglycosidically Tethered 5â-Nucleotides Constrained to a Highly Biologically Relevant Profile
An unexpected product from the cyclodesulfurization of 5â[1â(3âmethoxycarbonyl)thioureido]â1â(βâDâribofuranosyl)imidazoleâ4â carboxamide with dicyclohexylcarbodiimide
The treatment of 5â[1â(3âmethoxycarbonyl)thioureido]â1â(βâDâribofuranosyl)imidazoleâ4âcarboxamide with N,N' âdicyclohexylcarbodiimide in N,N âdimethylformamide has afforded 4âcyanoâ5â[1â(3âmethoxycarbonyl)âureido]â1â(βâDâribofuranosyl)imidazole.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/96319/1/5570230131_ftp.pd