326 research outputs found
Reactive Strength Index Modified Is a Valid Measure of Explosiveness in Collegiate Female Volleyball Players
Kipp, K, Kiely, MT, and Geiser, CF. Reactive strength index modified is a valid measure of explosiveness in collegiate female volleyball players. J Strength Cond Res 30(5): 1341–1347, 2016—The purpose of this study was to investigate the validity of the reactive strength index modified (RSImod) as a measure of lower body explosiveness. Fifteen female, National Collegiate Athletic Association Division I volleyball players performed vertical countermovement jumps (CMJs) while standing on a force plate. Each player performed 3 CMJs. The vertical ground reaction forces collected during each jump were used to calculate jump height, time to take-off, time to peak force, peak force, peak rate of force development, and peak power; the latter 3 variables were all normalized to body mass. Reactive strength index modified was calculated as the ratio between jump height and time to take-off. All variables, except for jump height, were then entered a factor analysis, which reduced the input data into 2 factors: a force factor and a speed factor. Although RSImod loaded more strongly onto the force factor, further analysis showed that RSImod loaded positively onto both force and speed factors. Visual analysis of the Cartesian coordinates also showed that RSImod loaded into the quadrant of greater force and speed abilities. These results indicate that the construct of RSImod, as derived from CMJ force-time data, captures a combination of speed-force factors that can be interpreted as lower body explosiveness during the CMJ. Reactive strength index modified therefore seems to be a valid measure to study lower body explosiveness
Effects of suggestion of difficulty on the fluency and rate of speech of children during oral reading
Biomechanical Determinants of the Reactive Strength Index During Drop Jumps
The Reactive Strength Index (RSI) is often used to quantify drop-jump (DJ) performance; however, not much is known about its biomechanical determinants. The purpose of this study was to investigate the correlations between the RSI and several biomechanical variables calculated from DJ performed with different initial drop heights. Twelve male NCAA Division I basketball players performed DJs from drop heights of 30, 45, and 60 cm. Force plates were used to calculate DJ performance parameters (ie, DJ height, contact time, and RSI) and DJ biomechanical variables (ie, vertical stiffness and eccentric/concentric energetics). Regression analyses were used to assess the correlations between variables at each drop height, and ANOVAs were used to assess the differences of all variables across drop heights. Follow-up analyses used 2 neural networks to determine if DJ performance and biomechanical data could accurately classify DJ trials by drop-height condition. Vertical-stiffness values were significantly correlated with RSI at each height but did not change across drop heights. Surprisingly, the RSI and other DJ parameters also did not vary across drop height, which resulted in the inability of these variables to accurately classify DJ trials. Given that vertical stiffness did not change across drop height and was highly correlated with RSI at each height, the RSI appears to reflect biomechanical behavior related to vertical stiffness during DJ. However, the inability of the RSI to accurately classify drop-height condition questions the use of RSI profiles established from DJs from different heights
Modulation of renal epithelial barrier function by mitogen-activated protein kinases (MAPKs): Mechanism of cyclosporine A–induced increase in transepithelial resistance
Modulation of renal epithelial barrier function by mitogen-activated protein kinases (MAPKs): Mechanism of cyclosporine A–induced increase in transepithelial resistance.BackgroundCyclosporine A (CsA) has been shown to increase transepithelial resistance in Madin-Darby canine kidney (MDCK) cells, and the mechanism may involve altered phosphorylation of junctional proteins. In this study, we examine the effect of the extracellular signal-regulated protein kinase (ERK) 1/2 and p38 mitogen-activated protein kinase (MAPK) pathways on the basal transepithelial resistance (TER) and on the CsA-induced increase in TER across MDCK monolayers. Here we present evidence that CsA may be mediating some of its effects through activation of the ERK 1/2 MAPK pathway.MethodsMDCK cells were treated with CsA (4.2 μmol/L) and paracellular permeability was assessed by measuring TER. The role of the ERK 1/2 and the p38 MAPK pathways in modulating TER was investigated using the inhibitors PD98059 and U0126 for ERK 1/2 and SB203580 for p38. ERK 1/2 and p38 phosphorylation/activation was also examined by Western blot analysis.ResultsCsA (4.2 μmol/L) increased the TER of MDCK monolayers. The ERK 1/2 inhibitor PD98059 decreased basal TER and also ameliorated the CsA-induced increase in TER. Similar results were found with the U0126 inhibitor of ERK 1/2. The p38 inhibitor SB203580 had no effect on the basal TER of the monolayers, however, SB203580 significantly augmented the CsA-induced increase in TER. CsA was shown to significantly activate ERK 1/2 and this activation by CsA was prevented by PD98059. Inhibition of the p38 pathway by SB203580 also resulted in activation of ERK 1/2 and this activation of ERK 1/2 was further enhanced by CsA. No effect of CsA or the inhibitors PD98059 or SB203580 on p38 phosphorylation was detected.ConclusionThe results presented here suggest that activation of the ERK 1/2 MAPK cascade is important in the regulation of the paracellular permeability in MDCK cells. Activation of this pathway appears to be pivotal to the CsA-induced increase in TER
Competition Volume and Changes in Countermovement Jump Biomechanics and Motor Signatures in Female Collegiate Volleyball Players
Kipp, K, Kiely, M, and Geiser, C. Competition volume and changes in countermovement jump biomechanics and motor signatures in female collegiate volleyball players. J Strength Cond Res 35(4): 970–975, 2021—The purpose of this study was to investigate the relationship between competition volume and preseason to postseason changes in countermovement jump (CMJ) biomechanics and motor signatures in female collegiate volleyball players. Ten National Collegiate Athletic Association Division I female volleyball players performed CMJs on force plates before (PRE) and after (POST) their season. Countermovement jump height was calculated, and 4 discrete biomechanical variables (peak body-mass normalized force [PeakF], peak body-mass normalized rate of force development [PeakRFD], movement time [TIME], and the ratio between eccentric and total movement time [EccT:TIME]) were calculated. A factor analysis of the 4 biomechanical variables was used to identify CMJ motor signatures. The total number of sets played by each player was used to define total competition volume for the season. Correlation coefficients were used to investigate the associations between competition volume and changes in CMJ height, discrete biomechanical variables, and the components of the CMJ motor signature. The statistical analysis indicated that team-average jump height did not change over the course of the season. However, competition volume was negatively associated with changes in CMJ height, such that decreases in CMJ height over the course of the season occurred in players who played large numbers of sets. Although CMJ during POST testing was characterized by longer TIME and greater PeakRFD, CMJ motor signatures did not change and suggest that the female volleyball players in this study retained their preferred jumping strategy across the season. Given that decreases in CMJ height were most pronounced in players who played the most sets, and scored the most points during the season, future research may need to focus on player- or position-specific interventions that help players retain CMJ performance in the face of the competitive demands of a collegiate volleyball season
Mechanical Demands of the Hang Power Clean and Jump Shrug: A Joint-level Perspective
The purpose of this study was to investigate the joint- and load-dependent changes in the mechanical demands of the lower extremity joints during the hang power clean (HPC) and the jump shrug (JS). Fifteen male lacrosse players were recruited from an NCAA DI team, and completed three sets of the HPC and JS at 30%, 50%, and 70% of their HPC 1-Repetition Maximum (1-RM HPC) in a counterbalanced and randomized order. Motion analysis and force plate technology were used to calculate the positive work, propulsive phase duration, and peak concentric power at the hip, knee, and ankle joints. Separate three-way analysis of variances were used to determine the interaction and main effects of joint, load, and lift type on the three dependent variables. The results indicated that the mechanics during the HPC and JS exhibit joint-, load-, and lift-dependent behavior. When averaged across joints, the positive work during both lifts increased progressively with external load, but was greater during the JS at 30% and 50% of 1-RM HPC than during the HPC. The JS was also characterized by greater hip and knee work when averaged across loads. The joint-averaged propulsive phase duration was lower at 30% than at 50% and 70% of 1-RM HPC for both lifts. Furthermore, the load-averaged propulsive phase duration was greater for the hip than the knee and ankle joint. The jointaveraged peak concentric power was the greatest at 70% of 1-RM for the HPC and at 30% to 50% of 1-RM for the JS. In addition, the joint-averaged peak concentric power of the JS was greater than that of the HPC. Furthermore, the load-averaged peak knee and ankle concentric joint powers were greater during the execution of the JS than the HPC. However, the loadaveraged power of all joints differed only during the HPC, but was similar between the hip and knee joints for the JS. Collectively, these results indicate that compared to the HPC the JS is characterized by greater hip and knee positive joint work, and greater knee and ankle peak concentric joint power, especially if performed at 30 and 50% of 1-RM HPC. This study provides important novel information about the mechanical demands of two commonly used exercises and should be considered in the design of resistance training programs that aim to improve the explosiveness of the lower extremity joints
CHANGES IN PRINCIPAL COMPONENT STRUCTURE OF COUNTERMOVEMENT JUMPS AFTER A VOLLEYBALL SEASON
The purpose of this study was to investigate changes in the principal component structure of countermovement jumps (CMJ) in female volleyball players over the course of a competitive season. Eleven NCAA Division I female volleyball players performed CMJs on a force plate before and after a competitive season. Discrete biomechanical variables were extracted from the force-time records of all CMJs and entered into a factor analysis. The analysis yielded two factors that could account for the biomechanical structure of the CMJs: a temporal and a force factor. Although no differences in factor scores were identified between pre- and post-season testing sessions, sub-group analysis highlighted large individual changes in temporal and force factor scores
The Effect of Cortisone on Mitotic Activity in the Maxillary Incisor of the Young Female Albino Rat
The Effect of Cortisone on the Rate of Eruption, DNA Synthesis, and Mitotic Activity in the Maxillary Incisor of the Female Albino Rat
Special Issue Editorial: Equality, Diversity, and Inclusion in IS Education
This editorial piece introduces a special issue of the Journal of Information Systems Education (JISE) on the topic of equality, diversity, and inclusion (EDI) in IS education. A number of contemporary issues are raised, such as inequality and barriers pertaining to gender, ethnicity, disability, sexuality, and socio-economic status. A set of research questions relating to EDI within IS education is set out, thus inviting further work within this important and under-researched area of our field
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