Minimal covers of the prisms and antiprisms

This paper contains a classication of the regular minimal abstract polytopes that act as covers for the convex polyhedral prisms and antiprisms. It includes a detailed discussion of their topological structure, and completes the enumeration of such covers for convex uniform polyhedra. Additionally, this paper addresses related structural questions in the theory of string C-groups.Comment: 22 pages, 8 figure

Archeological Survey of the South Tyger Watershed

At the request of the Soil Conservation Service an archeological survey was conducted by the Institute of Archeology and Anthropology, University of South Carolina on three proposed reservoir projects in the South Tyger River Watershed, Greenville County, South Carolina. The survey took place in February 1975 and revealed eight previously unrecorded sites in the watershed area. None of these sites are of a significance to warrant further extensive investigation, and there is little possibility that the reservoir projects will destroy any significant archeological sites.https://scholarcommons.sc.edu/archanth_books/1058/thumbnail.jp

Doctor of Philosophy

dissertationDrug-free macromolecular therapeutics are a new paradigm in polymer-based nanomedicines. Instead of carrying cytotoxic small molecular weight drugs, drug-free macromolecular therapeutics crosslink proteins in the cell membrane through hybridization of oligonucleotides to initiate apoptosis signaling. However, the mechanism of the nanomedicines was not fully understood. To study the mechanism and to better understand the interactions between the therapeutics and the cell membrane, super-resolution optical microscopy was used. Super-resolution imaging was performed on Raji B cells treated with the drug-free conjugates. The clustering of CD20 and lipid rafts was quantified. Lipid raft cluster size increased after treatment with drug-free conjugates. Drug-free conjugates induced apoptosis in a lipid raft-dependent mechanism where stable lipid rafts are needed for proper initiation of apoptosis. Direct stochastic optical reconstruction microscopy revealed nanoscale differences in membrane distribution of CD20 and lipid rafts. Pair-correlation analysis of super-resolution images showed lipid raft sizes of ~200 nm in cells treated with drug-free conjugates. General applicability of direct stochastic optical reconstruction microscopy to studying drug-delivery systems was also demonstrated. Two conceptually different polymer-based therapeutics were labeled with 4 different synthetic fluorophores, and three-dimensional (3D) direct stochastic optical reconstruction microscopy was conducted at different time points to track localization of the therapeutic components. An internalized polymer conjugate was localized in clusters at 4 h, but after 24 h, the polymer released into the cytosol a fluorophore attached via an enzymatically degradable peptide. Pair-correlation functions of the dye attached to the polymer and the released dye showed changes in their decay lengths between 4 h and 24 h. The pair-correlation function of the released dye showed random distribution after 24 h. Using reversible addition?fragmentation chain-transfer (RAFT) polymerization, branched and star polymers were synthesized to study the effect of architecture on apoptosis induction in Raji B cells. A new chain transfer monomer was synthesized in order to produce controlled branched polymers in RAFT polymerization. A degradable tetra-functional chain transfer agent was also synthesized. The star chain transfer agent produced degradable star polymers of high molecular weight (~170 kDa). Drug-free conjugates were synthesized to produce linear, branched, and star polymer-MORF2 conjugates. Apoptosis in Raji B cells was measured but the three different architectures induced the same levels of apoptosis as measure by annexin V and caspase 3

The Ashley River: A Survey of Seventeenth Century Sites

https://scholarcommons.sc.edu/archanth_books/1183/thumbnail.jp

Disability and the Counseling Relationship: What Counselors Need to Know

Disability is often misunderstood by counseling professionals and society. More often than not, persons without disability perceive it as a negative event and as something undesired, although this is not necessarily the experience or belief of many persons with a disability. Counselors that work with persons with disabilities and their families need to understand the experience and process of disability. Unfortunately, many counseling and psychology programs do not offer extensive training in this area. In an effort to enhance counselors’ understanding and effectiveness when counseling persons with disabilities, the authors provide pertinent and relevant information to help individuals respond successfully and creatively to their disabilities

Marcuse on The Two Dimensions of Advanced Industrial Society and The Significance of His Thought Today

Herbert Marcuse was a philosopher and social theorist who wrote extensively about the dynamics of social change in the technologically advanced societies of the Western world. Motivated by the desire to see humanity develop societies that would allow for individuals to live a free and happy existence, Marcuse critiqued the existing societies of his time. Although Marcuse’s main work, One-Dimensional Man, is over forty years old, it can continue to offer us new insights today. I believe that Marcuse’s thought offers a powerful framework for analyzing our contemporary society. In this project I distill this framework, what could be called the ‘Marcuse-spectacles’, and use it to illuminate structural forces in our society that lead to the triumph of conformist ways of thinking over critical ways of thinking. This newfound understanding is then applied to specific ways of combating the withering of a sphere for public discourse, a pillar for a healthy democracy. Topics discussed include Internet freedom and the importance of the humanities to democracy. I argue that reading Marcuse not only reveals to us something that lay before us unseen, but that what is learned is of great importance if you value a flourishing democratic process