Allele must be present in bone marrow derived cells to mediate DBA/2J glaucoma-5

E determined by ELISA. IL18 levels are expressed as mean +/- SEM from 5 aqueous humor samples in each group. Quantitative RT-PCR analysis comparing expression levels of IL18 transcript in ciliary body enriched dissections of 10.5 mo old D2, D2.and B6.mice. The threshold cycle was calculated with normalization to and values are expressed as mean +/- SEM, with 3–5 samples in each group.<p><b>Copyright information:</b></p><p>Taken from "allele must be present in bone marrow derived cells to mediate DBA/2J glaucoma"</p><p>http://www.biomedcentral.com/1471-2156/9/30</p><p>BMC Genetics 2008;9():30-30.</p><p>Published online 10 Apr 2008</p><p>PMCID:PMC2373794.</p><p></p

Absence of glaucoma in DBA/2J mice homozygous for wild-type versions of and -2

<p><b>Copyright information:</b></p><p>Taken from "Absence of glaucoma in DBA/2J mice homozygous for wild-type versions of and "</p><p>http://www.biomedcentral.com/1471-2156/8/45</p><p>BMC Genetics 2007;8():45-45.</p><p>Published online 3 Jul 2007</p><p>PMCID:PMC1937007.</p><p></p>on. . Side view dimensions of the anterior chamber. D2-eyes show no IPD but have a distinct form of ISA where the iris appears 'roughened'. D2-eyes have no transillumination defects and normal anterior chamber morphology (more than 20 eyes were analyzed from a variety of ages, images shown here are from a 13 months old mouse). . IOP measurements in D2-mice. Individual IOP readings are plotted as circles. The solid horizontal line indicates 21 mmHg, a value considered to be glaucoma-suspect in people. No 'high' IOP readings were seen in 97 eyes measured. Also, there is no significant change in IOP levels comparing 4 months old D2-mice to the 8, 10, 12 or 14 months old groups (p > 0.37 for all comparisons)