Extent of clustering within gene families.

<p>Frequencies of Ensembl gene family counts grouped by the percentage of family members contained within paraclusters (only families with 10 or more family members were counted).</p

Most abundant superfamily domains in paraclusters.

<p>The top 5 superfamilies having the most paracluster genes were selected from each vertebrate species tested and the number of genes along with the superfamily rank is provided for each species. hs = human, xp = chimp, ru = macaque, mm = mouse, rn = rat, dg = dog, bv = cow, op = opossum, gg = chicken, da = zerbrafish.</p

Frequency distribution of distances between structurally related genes.

<p>(a) Frequencies of distances between structurally related genes across the human genome (blue) as compared to the same data generated from randomly permuted genomes (red). (b) Frequencies of distances to the nearest structurally related gene for all human genes (blue) as compared to the same data generated from randomly permuted genomes (red).</p

Paracluster sizes.

<p>(a) Total gene count in paraclusters as a function of paracluster size measured as the number of paralogs in each paracluster. Gene counts include (blue) and exclude (red) interstitial genes. The parenthetical text provides the number of paraclusters having the corresponding size. (b) Cumulative frequency distribution of distances (spans) between genes sharing the same paracluster.</p

Percent of shared paraclusters within clades.

<p>The percentage of paraclusters which have at least one in-paralog existing in a paracluster of any of the species analyzed within each clade.</p

Species comparison of genome wide clustering metrics.

<p>Cumulative frequency distribution of the percentage of genes in paraclusters within the genomes of a selected set of species as a function of paracluster sizes.</p

Counts of paracluster genes from each species.

<p>Counts of paracluster genes from each species.</p

Percent of species specific paraclusters and common paraclusters within clades.

<p>The ‘species specific’ column represents the percentage of paraclusters which have no in-paralogs clustered in any other species analyzed; the ‘common’ columns represent the percentage of paraclusters which have at least one in-paralog existing in a paracluster in all of the species analyzed within each clade.</p

Counts of human/mice paracluster genes found from each dataset.

<p>Counts of human/mice paracluster genes found from each dataset.</p

Counts of human paracluster genes found in common between datasets.

<p>Counts of human paracluster genes found in common between datasets.</p