Causes of Corruption:History, Geography, and Government

Corruption, which remains a serious problem in many countries, has prompted considerable research in recent years. This paper adds to the extant literature with insights on factors influencing corrupt activity. Using cross-country data for about 100 nations, the roles of national history, geography, and government are examined to see how they affect conditions for corruption, both qualitatively and quantitatively. The innovative aspects of this research include use of a wide set of historical, geographical, and governmental determinants of corruption, as well as detailed assessment of several previously considered determinants. The main issues addressed are the effects of the size and scope of government on the incidence of corruption across countries, and the significance of historical and geographic factors in corruption. Regarding the first question, the authors find the size and scope of government can significantly affect corruption. On the second, it is shown that historical institutional inertia in older countries and new rent-seeking opportunities in younger nations can encourage corruption, while certain geographic factors can mitigate corruption. The paper ends with discussion aimed at the policymaker.corruption; bribery; government size; government scope; rent-seeking; history; geography

A genome-wide survey of segmental duplications that mediate common human genetic variation of chromosomal architecture.

Recent studies have identified a small number of genomic rearrangements that occur frequently in the general population. Bioinformatics tools are now available for systematic genome-wide surveys of higher-order structures predisposing to such common variations in genomic architecture. Segmental duplications (SDs) constitute up to 5 per cent of the genome and play an important role in generating additional rearrangements and in disease aetiology. We conducted a genome-wide database search for a form of SD, palindromic segmental duplications (PSDs), which consist of paired, inverted duplications, and which predispose to inversions, duplications and deletions. The survey was complemented by a search for SDs in tandem orientation (TSDs) that can mediate duplications and deletions but not inversions. We found more than 230 distinct loci with higher-order genomic structure that can mediate genomic variation, of these about 180 contained a PSD. A number of these sites were previously identified as harbouring common inversions or as being associated with specific genomic diseases characterised by duplication, deletions or inversions. Most of the regions, however, were previously unidentified; their characterisation should identify further common rearrangements and may indicate localisations for additional genomic disorders. The widespread distribution of complex chromosomal architecture suggests a potentially high degree of plasticity of the human genome and could uncover another level of genetic variation within human populations

Assessing An Economics Programme: Hansen Proficiencies, ePortfolio, and Undergraduate Research

Numerous sources calling for more accountability in higher education are putting increased pressure on many economics departments to develop assessment plans. This paper discusses a set of principles for programmatic assessment gleaned from the assessment literature, while highlighting one US economic department's journey to develop an assessment of student learning outcomes based on Hansen's proficiencies. We explain the curriculum reforms that culminate with independent undergraduate research as suggested by the highest level of Hansen's proficiencies. We describe ePortfolios which showcase student abilities and integrate evidence of student learning across the curriculum. For departments without direct guidance from accreditation boards or other agencies, we put forth a process of forming programmatic assessment in economics.

A Physical Theory of the Competition that Allows HIV to Escape from the Immune System

Competition within the immune system may degrade immune control of viral infections. We formalize the evolution that occurs in both HIV-1 and the immune system quasispecies. Inclusion of competition in the immune system leads to a novel balance between the immune response and HIV-1, in which the eventual outcome is HIV-1 escape rather than control. The analytical model reproduces the three stages of HIV-1 infection. We propose a vaccine regimen that may be able to reduce competition between T cells, potentially eliminating the third stage of HIV-1.Comment: 5 pages, 2 figures, to appear in Phys. Rev. Let

COMMUNITY ECONOMICS: A SIMULATION MODEL FOR RURAL DEVELOPMENT PLANNERS

Community/Rural/Urban Development,

CRATE: A Simple Model for Self-Describing Web Resources

If not for the Internet Archive’s efforts to store periodic snapshots of the web, many sites would not have any preservation prospects at all. The barrier to entry is too high for everyday web sites, which may have skilled webmasters managing them, but which lack skilled archivists to preserve them. Digital preservation is not easy. One problem is the complexity of preservation models, which have specific meta-data and structural requirements. Another problem is the time and effort it takes to properly prepare digital resources for preservation in the chosen model. In this paper, we propose a simple preservation model called a CRATE, a complex-object consisting of undifferentiated metadata and the resource byte stream. We describe the CRATE complex object and compare it with other complex-object models. Our target is the everyday, personal, departmental, or community web site where a long-term preservation strategy does not yet exist

Creating Preservation-Ready Web Resources

There are innumerable departmental, community, and personal web sites worthy of long-term preservation but proportionally fewer archivists available to properly prepare and process such sites. We propose a simple model for such everyday web sites which takes advantage of the web server itself to help prepare the site\u27s resources for preservation. This is accomplished by having metadata utilities analyze the resource at the time of dissemination. The web server responds to the archiving repository crawler by sending both the resource and the just-in-time generated metadata as a straight-forward XML-formatted response. We call this complex object (resource + metadata) a CRATE. In this paper we discuss modoai, the web server module we developed to support this approach, and we describe the process of harvesting preservation- ready resources using this technique