Oltre il Naturalismo a teatro: studio sulle commedie di Italo Svevo

La trattazione riflette il percorso drammaturgico sveviano soffermandosi sulle tappe cruciali del processo di maturazione stilistica e tematica che porta l'autore a adottare, anche in ambito teatrale, moduli espressivi già riscontrati dalla critica nella produzione narrativa. Dalle suggestioni naturalistiche che animano le prime commedie, Svevo giunge progressivamente ad un tipo di teatro che , rivelando l'implicazione di influenze di matrice nordica ( in particolar modo delle commedie del norvegese Ibsen), si riveste di uno sperimentalismo trascurato dalla critica contemporanea a Svevo, sancendo, in un certo senso, la condizione di subalternità della produzione teatrale rispetto a quella narrativa di cui soffre l'opera sveviana. L'obbiettivo è quello di individuare le coordinate all'interno delle quali l'universo teatrale sveviano, sempre in bilico tra conservazione ed innovazione, prende forma, dando vita a personaggi che sfondano i limiti all'interno dei quali la stereotipizzazione dei propri ruoli li improgiona, permettendo a Svevo approdare ad esiti drammaturgici indiscutibilmente innovativi nel panorama drammaturgico italiano contemporaneo

O uso de processos estocásticos como recurso criativo no desenvolvimento de um sistema composicional

O desenvolvimento de sistemas composicionais (Pitombeira 2020) pode fazer uso da matemática como uma poderosa ferramenta para especificação de regras. A maior propriedade desse uso é que ela dá suporte à abstração, tornando-se um meio excelente para modelagem (Pressman 1994). Conceitos oriundos dela proporcionaram uma base para o processo composicional de Xenakis (Xenakis 1992). A estocástica, uma das áreas da matemática selecionada pelo compositor, pode ser aplicada à elaboração da arquitetura de um sistema de composição para combinar elementos pré-existentes da composição ou para trabalhar objetos musicais ou extramusicais, resultando na expansão do processo criativo. Com esse recurso, um sistema composicional markoviano denominado Dorotéia é proposto e como resultado aplicado da pesquisa, são elaboradas algumas obras, cada uma delas conduzida por trechos literários extraídos do livro do escritor oulipiano Italo Calvino (Calvino 1990)

Quality Traits of Some Cauliflower Cultivars Grown in the “Valle dell’Ofanto” Area (Italy) as Affected by Post-Harvest Storage

Some quality characteristics of the “Valle dell’Ofanto” cauliflower, that has been recently appointed the certification of collective brand, were investigated at Gaudiano (41°03’N; 15°42’E, Southern Italy, Basilicata Region). Six white head cauli-flower cultivars, characterized by a different length of the crop cycle (2 early, 2 medium and 2 late), were studied. The above cultivars were transplanted in open field at the middle of August 2004 and harvested from the middle of October 2004 to the end of March 2005. At harvest time, yield traits and head sizes of cauliflowers were measured. Among the qualitative traits, color, weight loss, total soluble solids, nitrate and vitamin C content were assessed on the fresh florets and after a storage period lasting 15 days at 0°C and 95% R.H. The “Valle dell’Ofanto” cauliflower was charac¬terized by a high content in sugars and vitamin C, even if significant differences in some qualitative parameters (e.g., vitamin C and nitrate content) were affected by cultivars and crop cycle length. On the other hand, the storage at controlled tempera¬ture and R.H. did not substantially change the qualitative characteristics of the heads, but caused only a slight increase of dry matter and soluble solids levels, especially in those cultivars more susceptible to weight loss

P-Glycoprotein Expression in Acute Myeloid Leukaemia Cells at Diagnosis: Its relationship to Daunorubicin or Idarubicin Induction Therapy and Survival.

We investigated the expression of P-glycoprotein (P-gp) in 50 adults with de novo diagnosed acute myeloid leukaemia (AML) and the relationship between presence of P-gp in leukaemic cells and efficacy, as remission induction and survival rate, of two different anthracyclines, daunorubicin (DNR) and idarubicin (IDR). We found that 30 out of 50 patients (60%) were negative (Group 1) and 20 (40%) were positive (Group 2) for P-gp expression evaluated by mean of MRK16 MoAb using a cut-off of 10% positive cells. Thirty-five out of 50 patients (70%) obtained complete remission (CR); depending on P-gp expression, the CR rate was 80% for group 1 and 45% for group 2 (p < 0.005). The median duration of overall survival was 20 months for patients in Group 1 as compared with 10 months for patients of Group 2 (p < 0.005). Regarding the anthracycline used, no significant difference in CR was observed in patients of Group 1 (75% of CR with DNR vs. 90% with IDR); Group 2 obtained 40% of CR with DNR vs. 70% with IDR (p < 0.005). The median duration of overall survival (OS) with the two regimens was comparable in Group 1, while it was significantly longer in patients of Group 2 treated with IDR compared with DNR regimen (p < 0.005). These results confirm the prognostic value of P-gp expression in AML at first appearance and we suggest that idarubicin could be a valid anthracycline drug in the treatment of AML to be evaluated as potential drug of choice in patients with primary or drug-induced multidrug resistance

Garlic (Allium spp.) viruses: detection, distribution and remediation attempts in a European garlic collection

Garlic is an important vegetable crop in numerous countries used as food and natural based medicine. Similar to the majority of vegetatively propagated plants, garlic may be affected by several viruses that can cause severe crop losses. The present study aimed to screen 105 garlic accessions (mother plants) from 5 European countries (Germany, Czech Republic, Poland, Italy, and France) for possible presence of Onion yellow dwarf virus (OYDV), Leek yellow stripe virus (LYSV), Garlic common latent virus (GCLV) and Shallot latent virus (SLV). The occurrence of three Allexiviruses (GarV-A, GarV-B and GarV-C) in mixed assays was also investigated. Meristem-tip culture assays were performed in order to attempt eradication of the studied viruses. Garlic viruses identification was made by ELISA and RT-PCR. ELISA outcomes showed that all 105 garlic accessions were infected by different virus combinations. The OYDV and LYSV were identified, by ELISA, in all countries at 96% and 88,6% respectively and by RT-PCR at 99% and 96%. Furthermore, GCLV and SLV were detected by ELISA in about 88% and by RT-PCR at 89% and 90%, respectively with the exception of the studied Allexiviruses which were not amplified by RT-PCR with ALLEX1/ALLEX2 primers. Smaller meristem size (0,3-1,5 mm) led to better virus elimination efficiency (29%) compared to 8% obtained for the larger size (2-2,5 mm). The outcomes were opposite (16% vs. 90%) for plants regeneration. Virus elimination efficiency was linked to the virus type, e.g., OYDV and LYSV were eradicated at 90% while GCLV and Allexiviruses were difficult to eliminate (57,4% and 55,6% of eradication). Given the economic relevance of garlic crops worldwide and the frequently reported incidence of viral infections, it is important to make virusfree germplasm available. Therefore, investigating the garlic germplasm sanitary status and constantly improving it is of crucial importance aiming to increase the overall garlic production