1 research outputs found
Two Cu(II) complexes from an N-alkylated benzimidazole: synthesis, structural characterization, and biological properties
<div><p>Two mononuclear copper(II) complexes, [Cu(L)Cl<sub>2</sub>](CH<sub>3</sub>OH)<sub>2</sub> and [Cu(L)(NO<sub>3</sub>)<sub>2</sub>], were prepared and characterized by spectroscopic and analytic methods, where L is 2,6-bis(1-butyl-1<i>H</i>-benzo[<i>d</i>]imidazol-2-yl)pyridine. Molecular structures of the complexes were determined by X-ray diffraction. The X-ray data revealed that the complexes are mononuclear and coordination geometry around Cu(II) is distorted square pyramidal. The complexes were screened for their <i>in vitro</i> antibacterial and antifungal activities. The complexes show moderate antifungal activities against <i>Saccharomyces cerevisiae</i>, <i>Candida utilis,</i> and <i>Candida albicans</i>. Moreover, the complexes inhibit the development of <i>Escherichia coli</i> and <i>Klebsiella pneumoniae</i>.</p></div