14 research outputs found

    Preschool Behavioral and Social-Cognitive Problems as Predictors of (Pre)adolescent Disruptive Behavior

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    This article describes preschool social understanding and difficult behaviors (hot temper, disobedience, bossiness and bullying) as predictors of oppositional defiant disorder (ODD) and aggressive conduct disorder (ACD) in a Dutch population sample of (pre)adolescents (N = 1943), measured at age 10–12 and at age 13–15. ODD and ACD were assessed by the Child Behavior Checklist and the Youth Self-Report, preschool behavior was evaluated by the parental questionnaire ‹How was your child as a preschooler? (age 4–5)’. Adjusted for each other, all difficult preschool behaviors except bullying were associated with adolescent ODD, while only bullying significantly predicted adolescent ACD. Furthermore, the results suggest a qualitative difference between ODD and ACD in terms of the social component of the disorders: poor preschool social understanding was associated with the development of ACD but not of ODD; and poor social understanding interacted with difficult preschool behaviors to predict later ACD but not ODD. The associations did not differ between boys and girls, and were roughly similar for preadolescent (age 10–12) and early adolescent (age 13–15) outcomes. The finding that poor social understanding was implicated in the development of ACD but not in the development of ODD may help to demarcate the individuality of each disorder and offer leads for (differential) treatment strategies

    Preschool hyperactivity specifically elevates long-term mental health risks more strongly in males than females: a prospective longitudinal study through to young adulthood

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    Evidence of continuities between preschool hyperactivity and adult mental health problems highlight the potential value of targeting early identification and intervention strategies. However, specific risk factors are currently unclear. This large-scale prospective longitudinal study aimed to identify which hyperactive preschoolers are at greatest long-term risk of poor mental health. One hundred and seventy children (89 females) rated as hyperactive by their parents and 88 non-hyperactive controls (48 females) were identified from a community sample of 4,215 3 year-olds. Baseline data relating to behavioral/emotional problems and background characteristics were collected. Follow-up mental health and functional impairment outcomes were collected between 14 and 25 years of age. At age 3 years, males and females in the hyperactive group had similarly raised levels of hyperactivity and other behavior problems. In adolescence/young adulthood, these individuals showed elevated symptoms of ADHD, conduct disorder, mood disorder, anxiety and autism, as well as functional impairment. Preschool hyperactivity was strongly predictive of poor adolescent/adult outcomes for males across domains with effects being specifically driven by hyperactivity. For females, the effects of preschool hyperactivity were smaller and dropped to non-significant levels when other preschool problems were taken into account. Environmental risk factors also differed between the sexes, although these may also have been mediated by genetic risk. In conclusion, these results demonstrate marked sex differences in preschool predictors of later adolescent/adult mental health problems. Future research should include a measure of preschool inattention as well hyperactivity. The findings highlight the potential value of tailored approaches to early identification strategies

    The effect of irrigated land-use intensification on the topsoil physical properties of a pastoral silt loam

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    In Canterbury, New Zealand, there has been a widespread conversion of dryland sheep grazing to more intensive irrigated dairying. We determined the effects of these land uses on soil physical properties, and water release characteristics, on adjacent sites: a centre-pivot sprinkler-irrigated dairy farm site, a dryland sheep site, and a non-grazed, non-irrigated control site. Despite the Pallic Soil being well drained, greater soil compaction occurred at the dairy site than at other sites, to at least 30 cm depth. The dairy site typically had significantly lower total porosity and macroporosity, and greater bulk density and volumetric water content, than the other sites. Available water capacity varied but was greater at the dairy site (0–30 cm) than at the sheep site and control site. Further research is required across more farms and soils to confirm these results in other conditions

    Land-use intensification and dairy effluent effects on soil water repellency and soil carbon of a silt loam topsoil

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    In Canterbury, New Zealand, there has been widespread conversion of dryland sheep grazing to more intensive irrigated dairying. We determined the effects of these land uses on soil carbon on a centre-pivot sprinkler-irrigated dairy farm site, a dryland sheep site, and a non-grazed control site. The dairy site had significantly greater carbon density and carbon storage at 10–20 cm and 0–30 cm depths than the sheep farm site. The dairy farm site had significantly greater carbon stock (equivalent soil mass method) than the sheep farm site at 10–20 cm depth. The dairy farm site intensification did not adversely affect soil carbon, including carbon stock by the equivalent soil mass method. The effects of dairy effluent application on soil water repellency and water movement were investigated. The dairy site had significantly greater subcritical repellency index than the sheep site and a dairy effluent site. Further research is required across more farms and soils to confirm these results in these land uses and under other management and climate conditions

    C-type lectins in immunity and homeostasis

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    The authors thank the Wellcome Trust, the UK Medical Research Council (MRC), the MRC Centre for Medical Mycology at the University of Aberdeen and Arthritis Research UK for financial support. The authors apologize to colleagues whose many valuable contributions could not be cited owing to space constraints.Peer reviewedPostprintPostprintPostprintPostprin

    Can broad-spectrum multinutrients treat symptoms of antenatal depression and anxiety and improve infant development? Study protocol of a double blind, randomized, controlled trial (the ‘NUTRIMUM’ trial)

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