1 research outputs found
Unravelling the Gut Microbiota of Cow’s Milk–Allergic Infants, Their Mothers, and Their Grandmothers
The gut microbiome constitutes a highly complex
ecosystem in which bacteria are the most prominent
components. Around 70% of primary colonization of the gut
microbiota is maternal in origin [1], and the first 1000 days
of life are crucial for the development of the intestinal
microbiota [2]. Despite its early formation, the gut microbiota
is highly dynamic and dependent on host-associated
confounding factors such as age, diet, antibiotics, lifestyle, and
environmental conditions [3,4]. Alterations in gut microbiota
have been described in people with different types of allergy,
including cow’s milk allergy (CMA)This work was supported by Instituto de Salud Carlos
III (PI17/01087) and Fundación Sociedad Española
de Alergia e Inmunología Clínica (FSEAIC_2016). It
was cofunded by the European Regional Development
Fund “Investing in your future” for the Thematic
Network and Co-operative Research Centers ARADyAL
RD16/0006/0015 and RD16/0006/0026. It was additionally
supported by the Ministry of Science, Innovation in Spain
(PCI2018-092930), cofunded by the European program
ERA HDHL - Nutrition & the Epigenome, project Dietary
Intervention in Food Allergy: Microbiome, Epigenetic and
Metabolomic interactions (DIFAMEM). DR and EZ-V
acknowledge funding from the Spanish Ministry of Science,
Innovation and Universities (RTI2018-095166-B-I00).
CU acknowledges funding from the Spanish Ministry
of Economy (SAF2017-90083-R). TCB-T thanks CEUInternational Doctoral School (CEINDO) for his fellowship