High-Precision Lattice QCD Confronts Experiment

We argue that high-precision lattice QCD is now possible, for the first time, because of a new improved staggered quark discretization. We compare a wide variety of nonperturbative calculations in QCD with experiment, and find agreement to within statistical and systematic errors of 3% or less. We also present a new determination of alpha_msbar(Mz); we obtain 0.121(3). We discuss the implications of this breakthrough for phenomenology and, in particular, for heavy-quark physics.Comment: 2 figures, revte

Predictions from Lattice QCD

In the past year, we calculated with lattice QCD three quantities that were unknown or poorly known. They are the $q^2$ dependence of the form factor in semileptonic $D\to Kl\nu$ decay, the decay constant of the $D$ meson, and the mass of the $B_c$ meson. In this talk, we summarize these calculations, with emphasis on their (subsequent) confirmation by experiments.Comment: v1: talk given at the International Conference on QCD and Hadronic Physics, Beijing, June 16-20, 2005; v2: poster presented at the XXIIIrd International Symposium on Lattice Field Theory, Dublin, July 25-3

Leptonic decay constants f_Ds and f_D in three flavor lattice QCD

We determine the leptonic decay constants in three flavor unquenched lattice QCD. We use O(a^2)-improved staggered light quarks and O(a)-improved charm quarks in the Fermilab heavy quark formalism. Our preliminary results, based upon an analysis at a single lattice spacing, are f_Ds = 263(+5-9)(+/-24) MeV and f_D = 225(+11-13)(+/-21) MeV. In each case, the first reported error is statistical while the is the combined systematic uncertainty.Comment: Talk presented at Lattice2004(heavy), Fermilab, June 21-26, 2004. 3 pages, 2 figure

Semileptonic D->pi/K and B->pi/D decays in 2+1 flavor lattice QCD

We present results for form factors of semileptonic decays of $D$ and $B$ mesons in 2+1 flavor lattice QCD using the MILC gauge configurations. With an improved staggered action for light quarks, we successfully reduce the systematic error from the chiral extrapolation. The results for $D$ decays are in agreement with experimental ones. The results for B decays are preliminary. Combining our results with experimental branching ratios, we then obtain the CKM matrix elements $|V_{cd}|$, $|V_{cs}|$, $|V_{cb}|$ and $|V_{ub}|$. We also check CKM unitarity, for the first time, using only lattice QCD as the theoretical input.Comment: Talk presented at Lattice2004(heavy); 3 pages, 3 figure

Charmed meson decay constants in three-flavor lattice QCD

We present the first lattice QCD calculation with realistic sea quark content of the D^+ meson decay constant f_{D^+}. We use the MILC Collaboration's publicly available ensembles of lattice gauge fields, which have a quark sea with two flavors (up and down) much lighter than a third (strange). We obtain f_{D^+} = 201 +/- 3 +/- 17 MeV, where the errors are statistical and a combination of systematic errors. We also obtain f_{D_s} = 249 +/- 3 +/- 16 MeV for the D_s meson.Comment: note added on recent CLEO measurement; PRL versio

The Manganese Transporter MntH Is a Critical Virulence Determinant for Brucella abortus 2308 in Experimentally Infected Mice▿

The gene designated BAB1_1460 in the Brucella abortus 2308 genome sequence is predicted to encode the manganese transporter MntH. Phenotypic analysis of an isogenic mntH mutant indicates that MntH is the sole high-affinity manganese transporter in this bacterium but that MntH does not play a detectable role in the transport of Fe2+, Zn2+, Co2+, or Ni2+. Consistent with the apparent selectivity of the corresponding gene product, the expression of the mntH gene in B. abortus 2308 is repressed by Mn2+, but not Fe2+, and this Mn-responsive expression is mediated by a Mur-like repressor. The B. abortus mntH mutant MWV15 exhibits increased susceptibility to oxidative killing in vitro compared to strain 2308, and a comparative analysis of the superoxide dismutase activities present in these two strains indicates that the parental strain requires MntH in order to make wild-type levels of its manganese superoxide dismutase SodA. The B. abortus mntH mutant also exhibits extreme attenuation in both cultured murine macrophages and experimentally infected C57BL/6 mice. These experimental findings indicate that Mn2+ transport mediated by MntH plays an important role in the physiology of B. abortus 2308, particularly during its intracellular survival and replication in the host