1 research outputs found
Cavity-Type DNA Origami-Based Plasmonic Nanostructures for Raman Enhancement
DNA origami has been established
as addressable templates for site-specific anchoring of gold nanoparticles
(AuNPs). Given that AuNPs are assembled by charged DNA oligonucleotides,
it is important to reduce the charge repulsion between AuNPs–DNA
and the template to realize high yields. Herein, we developed a cavity-type
DNA origami as templates to organize 30 nm AuNPs, which formed dimer
and tetramer plasmonic nanostructures. Transmission electron microscopy
images showed that high yields of dimer and tetramer plasmonic nanostructures
were obtained by using the cavity-type DNA origami as the template.
More importantly, we observed significant Raman signal enhancement
from molecules covalently attached to the plasmonic nanostructures,
which provides a new way to high-sensitivity Raman sensing