4,691 research outputs found

    Localization in Khovanov homology

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    We construct equivariant Khovanov spectra for periodic links, using the Burnside functor construction introduced by Lawson, Lipshitz, and Sarkar. By identifying the fixed-point sets, we obtain rank inequalities for odd and even Khovanov homologies, and their annular filtrations, for prime-periodic links in S3S^3

    Tunable Broadband Transparency of Macroscopic Quantum Superconducting Metamaterials

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    Narrow-band invisibility in an otherwise opaque medium has been achieved by electromagnetically induced transparency (EIT) in atomic systems. The quantum EIT behaviour can be classically mimicked by specially engineered metamaterials via carefully controlled interference with a "dark mode". However, the narrow transparency window limits the potential applications that require a tunable wide-band transparent performance. Here, we present a macroscopic quantum superconducting metamaterial with manipulative self-induced broadband transparency due to a qualitatively novel nonlinear mechanism that is different from conventional EIT or its classical analogs. A near complete disappearance of resonant absorption under a range of applied rf flux is observed experimentally and explained theoretically. The transparency comes from the intrinsic bi-stability and can be tuned on/ off easily by altering rf and dc magnetic fields, temperature and history. Hysteretic in situ 100% tunability of transparency paves the way for auto-cloaking metamaterials, intensity dependent filters, and fast-tunable power limiters

    Speeding Up the Prototyping of Low-Fidelity User Interface Wireframes

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    Prototyping for user interfaces (UIs) is essential when it comes to giving an idea for how the final result will look and function. This allows both designers and stakeholders to test if all the project requirements are being fulfilled and the functionality of the UI, saving time and money further down the road when the final product is being made. However, current established prototyping tools have an emphasis on visual aesthetics without support for quickly producing low-fidelity prototyping. This leads to the initial prototyping process to be time-consuming and labor-intensive as designers need to start from scratch. In this research, we propose a solution that hopefully speeds up the low-fidelity UI prototyping process by streamlining the workflow. Based on previous research of scenario-based UI design and utilizing UI design patterns and sketching, we created a Figma plugin tool for guiding the creation of low-fidelity wireframe prototypes. We then conducted a user study which revealed that the plugin was easy to learn and use with a lower subjective workload for physical demand, temporal demand, and frustration. The contribution of our work is providing an alternative approach for designers and stakeholders to collaborate together and facilitate easy prototyping of low-fidelity UI wireframes

    Gene editing in yeast cells using the CRISPR/Cas9 system

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    https://scholarworks.moreheadstate.edu/student_scholarship_posters/1267/thumbnail.jp

    Biocatalytic Intramolecular C−H aminations via Engineered Heme Proteins: Full Reaction Pathways and Axial Ligand Effects

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    Engineered heme protein biocatalysts provide an efficient and sustainable approach to develop amine-containing compounds through C−H amination. A quantum chemical study to reveal the complete heme catalyzed intramolecular C−H amination pathway and protein axial ligand effect was reported, using reactions of an experimentally used arylsulfonylazide with hemes containing L=none, SH−, MeO−, and MeOH to simulate no axial ligand, negatively charged Cys and Ser ligands, and a neutral ligand for comparison. Nitrene formation was found as the overall rate-determining step (RDS) and the catalyst with Ser ligand has the best reactivity, consistent with experimental reports. Both RDS and non-RDS (nitrene transfer) transition states follow the barrier trend of MeO
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