22 research outputs found
Spruce chips stabilization in wood-cement materials: Effect of matrix composition
The paper presents research focused on the behaviour of wood-cement composites with a modified matrix. This matrix has an impact on the stabilization of the spruce wood content. Silicate matrix based on Portland and blended cement was modified by finely ground thermal power plant slag (TPPS) and limestone (LS). Four types of wood-cement composite were subjected to water immersion tests for 28 days. During water immersion, both swelling in thickness and mass changes were analysed. The amount of sugars and pH in leachate were determined after 7 day intervals. Mechanical properties and microstructures were analysed before and after water immersion. Different behaviour with regard to spruce chips stabilization was proved in dependence of wood-cement matrix modification. Differences in thickness, swelling and sugar leach indirectly indicate the influence of the wood-cement composites matrix composition on the stabilization of spruce chips contained in this matrix. Boards with the matrix modified with thermal power plant slag showed the highest thickness swelling (%) and sugar leaching (0,042 %). Therefore, in the presence of thermal power plant slag modified matrix, spruce chips are more susceptible to sugar leach. The results of strength characteristics confirmed that sugars leached during hydration and after longer contact of wood-cement composites with water have no negative influence in their final properties in the case of all materials tested (reference and modified).  
Efficacy of bevacizumab and chemotherapy in the first-line treatment of metastatic colorectal cancer: broadening KRAS-focused clinical view
The Behavior of Cement-Bonded Particleboard with Modified Composition under Static Load Stress
This article presents research on the behavior of cement-bonded particleboards under mechanical stress caused by the static load. The composition of the boards was modified using alternative raw materials–dust (DU) forming during the processing of cement-fibre boards and particle mixture (PM) generated in the production of cement-bonded particleboards. The particleboards (1-year-old) were subjected to an adverse environment (100 to 250 frost cycles). Mechanical parameters were tested, and the development of defects during static load of the boards by bending was analyzed using acoustic emission. Particleboards with modified compositions are slightly more resistant to adverse environments. The results of the acoustic emission showed the different types of defects occurring under stress by bending. Standard-composition particleboards showed defects located mainly under the cylindrical stress-test head. The modified boards showed larger location distribution of the occurring defects that were also concentrated further away from the cylindrical stress head. The energy during the occurrence of defects was higher in the modified boards in the location of weight application than in the reference boards
Performance Test of the Air-Cooled Finned-Tube Supercritical CO2 Sink Heat Exchanger
This technical paper presents results of an air-cooled supercritical CO2 (sCO2) finnedtube sink heat exchanger (HX) performance test comprising wide range of variable parameters (26-166 C, 7-10 MPa, 0.1-0.32 kg/s). The measurement covered both supercritical and subcritical pressures including transition of pseudocritical region in the last stages of the sink HX. The test was performed in a newly built sCO2 experimental loop which was constructed within Sustainable Energy (SUSEN) project at Research Centre Rez (CVR). The experimental setup along with the boundary conditions are described in detail; hence, the gained data set can be used for benchmarking of system thermal hydraulic codes. Such benchmarking was performed on the open source Modelica-based code ClaRa. Both steady-state and transient thermal hydraulic analyses were performed using the simulation environment DYMOLA 2018 on a state of the art PC. The results of calculated averaged overall heat transfer coefficients (using Gnielinski correlation for sCO2 and IPPE or VDI for the air) and experimentally determined alues shows reasonably low error ofp25% and - 10%. Hence, using the correlations for the estimation of the heat transfer in the sink HX with a similar design and similar conditions gives a fair error and thus is recommended.</p
Outcomes According to MSKCC Risk Score with Focus on the Intermediate-Risk Group in Metastatic Renal Cell Carcinoma Patients Treated with First-Line Sunitinib: A Retrospective Analysis of 2390 Patients
Background: The Memorial Sloan–Kettering Cancer Center (MSKCC) prognostic model has been widely used for the prediction of the outcome of metastatic renal cell carcinoma (mRCC) patients treated with systemic therapies, however, data from large studies are limited. This study aimed at the evaluation of the impact of the MSKCC score on the outcomes in mRCC patients treated with first-line sunitinib, with a focus on the intermediate-risk group. Methods: Clinical data from 2390 mRCC patients were analysed retrospectively. Progression-free survival (PFS), overall survival (OS), and objective response rate (ORR) were analysed according to the MSKCC risk score. Results: ORR, median PFS, and OS for patients with one risk factor were 26.7%, 10.1, and 28.2 months versus 18.7%, 6.2, and 16.2 months, respectively, for those with two risk factors (ORR: p = 0.001, PFS: p < 0.001, OS: p < 0.001). ORR, median PFS, and OS were 33.0%, 17.0, and 44.7 months versus 24.1%, 9.0, and 24.1 months versus 13.4%, 4.5, and 9.5 months in the favourable-, intermediate-, and poor-risk groups, respectively (ORR: p < 0.001, PFS: p < 0.001, OS: p < 0.001). Conclusions: The results of the present retrospective study demonstrate the suitability of the MSKCC model in mRCC patients treated with first-line sunitinib and suggest different outcomes between patients with one or two risk factors
Performance Test of the Air-Cooled Finned-Tube Supercritical CO2 Sink Heat Exchanger
This technical paper presents results of an air-cooled supercritical CO2 (sCO2) finnedtube sink heat exchanger (HX) performance test comprising wide range of variable parameters (26-166 C, 7-10 MPa, 0.1-0.32 kg/s). The measurement covered both supercritical and subcritical pressures including transition of pseudocritical region in the last stages of the sink HX. The test was performed in a newly built sCO2 experimental loop which was constructed within Sustainable Energy (SUSEN) project at Research Centre Rez (CVR). The experimental setup along with the boundary conditions are described in detail; hence, the gained data set can be used for benchmarking of system thermal hydraulic codes. Such benchmarking was performed on the open source Modelica-based code ClaRa. Both steady-state and transient thermal hydraulic analyses were performed using the simulation environment DYMOLA 2018 on a state of the art PC. The results of calculated averaged overall heat transfer coefficients (using Gnielinski correlation for sCO2 and IPPE or VDI for the air) and experimentally determined alues shows reasonably low error ofp25% and - 10%. Hence, using the correlations for the estimation of the heat transfer in the sink HX with a similar design and similar conditions gives a fair error and thus is recommended.RST/Reactor Physics and Nuclear Material
Computing all subtree repeats in ordered trees
International audienceWe consider the problem of computing all subtree repeats in a given labeled ordered tree. We first transform the tree to a string representing its postfix notation, and then present an algorithm based on the bottom-up technique to solve it. The proposed algorithm consists of two phases: the preprocessing phase and the phase where all subtree repeats are computed. The linear time and space complexity of the proposed algorithm are important parts of its quality