Additional file 1: of Resveratrol ameliorates prenatal progestin exposure-induced autism-like behavior through ERβ activation

Table S1. Sequences of primers for the real time quantitative PCR (qPCR). Figure S1. Postnatal resveratrol treatment increases expression of SOD2 and ERRα, while it has no effect on the expression of ERβ and SIRT1 in the hypothalamus and hippocampus of prenatal norethindrone exposed offspring. Figure S2. Both resveratrol and norethindrone treatment do not change the expression and activity of SIRT1 in the amygdala. Figure S3. Postnatal resveratrol treatment ameliorates prenatal norethindrone exposure-induced oxidative stress, dysfunction of mitochondria and lipid metabolism through ERβ activation. Figure S4. Prenatal resveratrol treatment prevents prenatal norethindrone exposure-induced epigenetic changes, oxidative stress, and the dysfunction of mitochondria and lipid metabolism. Data S1. Statistical details for Fig. 2. Data S2. Statistical details for Fig. 3. Data S3. Statistical details for Fig. 4. Data S4. Statistical details for Fig. 5. Data S5. Statistical details for Fig. 6. Data S6. Statistical details for Fig. 7. (DOCX 402 kb