camillo boito s capannone for the accademia di brera in milan reuse of a railway depot

The work concerns the project for the transfer of some departments of the Brera Academy to the area of Scalo Farini located in the centre of Milan. The area is central to the transformations of Milan, and the relocation of the departments of the Academy solves the problem of its development as a school. The transfer occupies the large post office warehouse in the centre of the area, which is the subject of a conservation and evaluation process for the insertion of the new functions

Effects of taping on knee joint position sense of female athletes across the menstrual cycle

Introduction: The rate of anterior cruciate ligament (ACL) tearing is more common in female athletes and one of thereasons is the effect of sex hormones. It was illustrated that knee joint position sense (JPS) isaltered across the menstrual cycle and its lowest level is at menses. Therefore, it’s important to find a method to reduce injury risk at menses. Thus, the purpose of this study was to evaluate the effect of taping as a stimulator of skin, on the knee JPS in healthy female athletes across the menstrual cycle with different levels of estrogen and progesterone. Materials and Methods: In this semi-experimental study, 16 healthy female athletes with regular menstrual cycle voluntarily participated. Knee JPS was measured at 3 menstrual cycle phases, before and after patellataping. JPS was evaluated by reproduction of the target angle (30° flexion) in standing position, from full extension. Serum estrogen and progesterone levels were collected in these 3 phases. Knee angles were measured by using a system comprised of skin markers, digital photography, and autoCAD software. Absolute error was considered as a dependent variable.Results: There was a significant difference between the knee JPS in 3 phases of measurement before taping (P=0.025), while no significant difference was found between knee JPS in 3 phases after taping (P=0.965). Conclusion: Findings of this study suggest that healthy female athletes have different levels of knee JPS across a menstrual cycle and its accuracy decreasesat menses. This differencecan be reduced by skin stimulatingmethods, such as taping. Therefore, kinesio taping would improve the knee JPSdeficiency at menses

Co-existence of various clinical and histopathological features of mycosis fungoides in a young female

Mycosis fungoides is the most common type of cutaneous T-cell lymphoma (CTCL) and a rare disorder that typically affects older adults with erythematous scaling patches and plaques. Hypopigmented patches are a rare clinical variant of the disease. Granulomatous mycosis fungoides (GMF) is also a rare type of CTCL. No particular clinical criteria are available for the diagnosis of GMF, because of its variable presentations, and so the detection of GMF is primarily considered as a histopathological diagnosis. Rarely, a co-existence of more than one clinical or histopathological feature of mycosis fungoides may be present. To the best of our knowledge this is the first report of MF that shows the simultaneous co-existence of more than one clinical and histopathological variant of MF. We present a 29-year-old female with clinical presentations of both classic and hypopigmented mycosis fungoides (MF), and also the histopathological features of the classic and granulomatous types of the disease

Per l’ampliamento dell’Accademia di Brera. Ricerche progettuali.

Scritti di Sandro Scarrocchia, Francesca Valli, Elisa Isella, Luca Monica, Giovanni Luca Ferreri, Agata Brusetti, Stefano Cusatelli, Paola Galbiati, Monica Manfredi, Gabriella Guarisco, Mehrnaz Rajabi, Giovanni Cattani Questi materiali di ricerca e di didattica sono il frutto di una collaborazione tra il Politecnico di Milano e l’Accademia di Belle Arti di Brera sul tema del progetto di ampliamento della stessa Accademia nell’area del dismesso Scalo ferroviario Farini a Milano. Oltre a una prima indagine istruttoria, sono raccolti sia “prototipi didattici” elaborati dal gruppo docente (capogruppo L. Monica), sia progetti degli allievi

Establishment and Characterization of Primary Cultures from Iranian Oral Squamous Cell Carcinoma Patients by Enzymatic Method and Explant Culture

Objectives: Oral Squamous Cell Carcinoma (OSCC) is the most frequent oral cancer worldwide. It is known as the eighth most common cancer in men and as the fifth most common cancer in women. Cytogenetic and biochemical studies in recent decades have emphasized the necessity of providing an appropriate tool for such researches. Cancer cell culture is a useful tool for investigations on biochemical, genetic, molecular and immunological characteristics of different cancers, including oral cancer. Here, we explain the establishment process of five primary oral cancer cells derived from an Iranian population. Materials and Methods: The specimens were obtained from five oral cancer patients. Enzymatic, explant culture and magnetic-activated cell sorting (MACS) methods were used for cell isolation. After quality control tests, characterization and authentication of primary oral cancer cells were performed by short tandem repeats (STR) profiling, chromosome analysis, species identification, and monitoring the growth, morphology and the expression of CD326 and CD133 markers. Results: Five primary oral cancer cells were established from an Iranian population. The flow cytometry results showed that the isolated cells were positive for CD326 and CD133 markers. Furthermore, the cells were free from mycoplasma, bacterial and fungal contamination. No misidentified or cross-contaminated cells were detected by STR analysis. Conclusions: Human primary oral cancer cells provide an extremely useful platform for studying carcinogenesis pathways of oral cancer in Iranian population. They may be helpful in explaining the ethnic differences in cancer biology and the individuality in anticancer drug response in future studies.