88 research outputs found

    Control of Local Mass Transfer in the Separated and Reattaching Flow by a Periodic Forcing

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    A numerical study based on the Large Eddy Simulation (LES) methodology was made of mass transfer in locally forced turbulent separated and reattaching flow over a backward facing step. The local forcing was given to the flow by a sinusoidally blowing /suction of the fluid into a separated shear layer. The Reynolds number was fixed at 33000 and Schmidt number at 1. The forcing frequency was varied in the range 0 St 2, where St is the Strouhal number of forcing. The obtained results revealed the existence of an optimum forcing frequency value, St = 0.25, in terms of the reduced reattachment length. At this frequency the mass transfer is significantly enhanced in the recirculation zone. The influence of the frequency and the amplitude of forcing, in the maximum mass transfer positions and the maximum Sherwood number, are analyzed

    Simulation of the Periodically Perturbed Separated and Reattaching Flow over a Backward-Facing Step

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    In this work, the Large Eddy Simulation (LES) methodology is used to study the effects of a periodic perturbation introduced into a separated shear layer behind a backward-facing step. This study carried out by acting on the two parameters characteristics of the perturbation: frequency and amplitude. The obtained results reveal the existence of an optimum perturbation frequency value, Stp = 0.25, in terms of the reduced reattachment length. At this perturbation frequency value, we observed an increase in the vortical shedding frequency in the reattachment zone with a significant change of the structure of the flow. The value of the optimum frequency appears to be independent of the perturbation amplitude. At this frequency the maximum decrease of reattachment length is 50% and the maximum increase of vortical shedding frequency is 43 % compared to the unperturbed case

    Resonant Andreev reflections in superconductor-carbon-nanotube devices

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    Resonant Andreev reflection through superconductor-carbon-nanotube devices was investigated theoretically with a focus on the superconducting proximity effect. Consistent with a recent experiment, we find that for high transparency devices on-resonance, the Andreev current is characterized by a large value and a resistance dip; low-transparency off-resonance devices give the opposite result. We also give evidence that the observed low-temperature transport anomaly may be a natural result of Andreev reflection process

    Carbon nanotube-based quantum pump in the presence of superconducting lead

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    Parametric electron pump through superconductor-carbon-nanotube based molecular devices was investigated. It is found that a dc current, which is assisted by resonant Andreev reflection, can be pumped out from such molecular device by a cyclic variation of two gate voltages near the nanotube. The pumped current can be either positive or negative under different system parameters. Due to the Andreev reflection, the pumped current has the double peak structure around the resonant point. The ratio of pumped current of N-SWNT-S system to that of N-SWNT-N system (I^{NS}/I^N) is found to approach four in the weak pumping regime near the resonance when there is exactly one resonant level at Fermi energy inside the energy gap. Numerical results confirm that in the weak pumping regime the pumped current is proportional to the square of the pumping amplitude V_p, but in the strong pumping regime the pumped current has the linear relation with V_p. Our numerical results also predict that pumped current can be obtained more easily by using zigzag tube than by using armchair tube

    Tight-binding parameters for charge transfer along DNA

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    We systematically examine all the tight-binding parameters pertinent to charge transfer along DNA. The π\pi molecular structure of the four DNA bases (adenine, thymine, cytosine, and guanine) is investigated by using the linear combination of atomic orbitals method with a recently introduced parametrization. The HOMO and LUMO wavefunctions and energies of DNA bases are discussed and then used for calculating the corresponding wavefunctions of the two B-DNA base-pairs (adenine-thymine and guanine-cytosine). The obtained HOMO and LUMO energies of the bases are in good agreement with available experimental values. Our results are then used for estimating the complete set of charge transfer parameters between neighboring bases and also between successive base-pairs, considering all possible combinations between them, for both electrons and holes. The calculated microscopic quantities can be used in mesoscopic theoretical models of electron or hole transfer along the DNA double helix, as they provide the necessary parameters for a tight-binding phenomenological description based on the π\pi molecular overlap. We find that usually the hopping parameters for holes are higher in magnitude compared to the ones for electrons, which probably indicates that hole transport along DNA is more favorable than electron transport. Our findings are also compared with existing calculations from first principles.Comment: 15 pages, 3 figures, 7 table

    Effectiveness of esterified whey proteins fractions against Egyptian Lethal Avian Influenza A (H5N1)

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    <p>Abstract</p> <p>Background</p> <p>Avian influenza A (H5N1) virus is one of the most important public health concerns worldwide. The antiviral activity of native and esterified whey proteins fractions (α- lactalbumin, β- lactoglobulin, and lactoferrin) was evaluated against A/chicken/Egypt/086Q-NLQP/2008 HPAI (H5N1) strain of clade 2.2.1 (for multiplicity of infection (1 MOI) after 72 h of incubation at 37°C in the presence of 5% CO<sub>2</sub>) using MDCK cell lines.</p> <p>Result</p> <p>Both the native and esterified lactoferrin seem to be the most active antiviral protein among the tested samples, followed by β- lactoglobulin. α-Lactalbumin had less antiviral activity even after esterification.</p> <p>Conclusion</p> <p>Esterification of whey proteins fractions especially lactoferrin and β-lactoglobulin enhanced their antiviral activity against H5N1 in a concentration dependent manner.</p

    Global economic burden of unmet surgical need for appendicitis

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    Background: There is a substantial gap in provision of adequate surgical care in many low-and middle-income countries. This study aimed to identify the economic burden of unmet surgical need for the common condition of appendicitis. Methods: Data on the incidence of appendicitis from 170 countries and two different approaches were used to estimate numbers of patients who do not receive surgery: as a fixed proportion of the total unmet surgical need per country (approach 1); and based on country income status (approach 2). Indirect costs with current levels of access and local quality, and those if quality were at the standards of high-income countries, were estimated. A human capital approach was applied, focusing on the economic burden resulting from premature death and absenteeism. Results: Excess mortality was 4185 per 100 000 cases of appendicitis using approach 1 and 3448 per 100 000 using approach 2. The economic burden of continuing current levels of access and local quality was US 92492millionusingapproach1and92 492 million using approach 1 and 73 141 million using approach 2. The economic burden of not providing surgical care to the standards of high-income countries was 95004millionusingapproach1and95 004 million using approach 1 and 75 666 million using approach 2. The largest share of these costs resulted from premature death (97.7 per cent) and lack of access (97.0 per cent) in contrast to lack of quality. Conclusion: For a comparatively non-complex emergency condition such as appendicitis, increasing access to care should be prioritized. Although improving quality of care should not be neglected, increasing provision of care at current standards could reduce societal costs substantially

    Metallic, magnetic and molecular nanocontacts

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    Scanning tunnelling microscopy and break-junction experiments realize metallic and molecular nanocontacts that act as ideal one-dimensional channels between macroscopic electrodes. Emergent nanoscale phenomena typical of these systems encompass structural, mechanical, electronic, transport, and magnetic properties. This Review focuses on the theoretical explanation of some of these properties obtained with the help of first-principles methods. By tracing parallel theoretical and experimental developments from the discovery of nanowire formation and conductance quantization in gold nanowires to recent observations of emergent magnetism and Kondo correlations, we exemplify the main concepts and ingredients needed to bring together ab initio calculations and physical observations. It can be anticipated that diode, sensor, spin-valve and spin-filter functionalities relevant for spintronics and molecular electronics applications will benefit from the physical understanding thus obtained
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