SARS-Cov-2 and hearing loss: Two sibling cases

Various neurological involvements have been reported associated with SARS-Cov-2 virus infection. Hearing loss has been reported in very few cases. It has been shown that the pathophysiological causes of hearing loss can be very different. We are open for discussion cases where two siblings, we bring into consideration the issues of genetic mechanisms may contribute to it. [Med-Science 2022; 11(2.000): 877-9

Distal symmetrical polyneuropathy due to organophosphate intoxication

While a cholinergic crisis picture is onset in intoxication of organophosphate compounds; a severe polyneuropathy mainly affecting the motor fibers is viewed lately following weeks. Cholinergic crisis may require intubation meanwhile lately onset neuropathy may be characterized by cranial nerve palsies, a hazy vision, ataxia and skin paresthesia. Exposure to substance could be progressed by respiratory tract and skin. 20-year-old male patient with muscle weakness and thinning in the hands and legs was admitted to our outpatient clinic. In his story; he had suicidal drunk pesticide 6 months ago, hospitalized due to loss of consciousness, given respiratory support in the intensive care unit for following 11 days. During the following period, sensory disorders involving numbness and pain, and thinning in the arms and legs were onset. At nerve conduction study, axonal polyneuropathy was identified: sensory fibers were protected, motor conduction velocities and amplitudes were extremely decreased. At needle EMG studies widespread denervation potentials were recorded to be more pronounced in the distal muscle groups. In the discussed case; a cholinergic crisis picture occurred after exposure to toxic agents in the acute phase, the patient was observed as intubated for a while, in the subacute phase a polyneuropathy mostly located in the proximal muscles was onset and muscle atrophies have emerged in the late phase. In this writing, an organophosphate intoxication case in which cholinergic crisis was set in earlier days, polyneuropathy picture was seen on subacute stage and muscle atrophies were confirmed on following weeks was discussed. [Med-Science 2017; 6(3.000): 588-91

Isolated unilateral hypoglossal nerve paralysis: A case report

Isolated unilateral hypoglossal nerve paralysis is a rare condition. The etiologic factors that may cause this are cancer metastases, infection, endocrine, neurological, autoimmune and vascular reasons. A 56-year-old male patient complained of swelling, speech impairment and biting the left side of the tongue for 2 years. [Med-Science 2017; 6(3.000): 613-

Cerebral venous thrombosis as a complication of leptospirosis

Leptospirosis is an acute infectious disease caused by a spirochete of the leptospira gender and it is characterized by severe vasculitis. It is not common for leptospirosis to present as a primary neurological disease. On the other hand, no study has been reported on the progression of cerebral venous thrombosis (CVT) in patients with leptospirosis so far. This is the first case reported which shows CVT as a complication after the leptospirosis infection. An acutely developed leptospirosis and post-infectious CVT in a 21-year-old soldier is described here. (C) 2006 The British Infection Society. Published by Elsevier Ltd. All rights reserved

Elastic characteristics of aorta in patients with epilepsy

Aim To investigate elastic characteristics of the aorta in patientswith epilepsy.Methods Seventy five patients with a diagnosis of epilepsy through clinical and EEG findings and age and sex matched, 50 healthy controls were included. Systolic and diastolic blood pressures plus systolic and diastolic diameter of the aortic root was measured. Aortic strain (AS) and aortic distensibility (AD) and aortic distensibility index (BSI) were calculated. Results The average age of the epilepsy group was 23.8.8 ± 8.2 years, and of the control group it was 24.1± 6.2 years (p>0.05). AS and AD were lower in the epileptic group while the aortic stiffness index was higher (10.4± 4.2 vs 16.9±0.2, p: 0.001, for AS; 8.7± 4.0 vs 17.2±0.1, p: 0.001, for AD and 20.1±0.1 vs 3.5±1.2, p: 0.001 for BSI). Conclusion Elastic characteristics of the aorta change in epileptic patients, with a decrease of the distensibility of the aorta and an increaseof the stiffness. After this preliminary study, new controlledstudies are needed