Rosa damascena oil improves SSRI-induced sexual dysfunction in male patients suffering from major depressive disorders: results from a double-blind, randomized, and placebo-controlled clinical trial

A substantial disadvantage of psychopharmacological treatment of major depressive disorder (MDD) with selective serotonin-reuptake inhibitors (SSRIs) is the impact on sexual dysfunction. The aim of the present study was to investigate whether the oil of Rosa damascena can have a positive influence on SSRI-induced sexual dysfunction (SSRI-I SD) of male patients who are suffering from MDD and are being treated with SSRIs.; In a double-blind, randomized, and placebo-controlled clinical trial, a total of 60 male patients treated with an SSRI and suffering from MDD (mean age =32 years) and SSRI-I SD were randomly assigned to take either verum (R. damascena oil) or a placebo. Patients completed self-ratings of depression and sexual function at baseline, at 4 weeks later, and at the end of the study, 8 weeks after it started.; Over time, sexual dysfunction improved more in the verum group than in the control group. Improvements were observed in the verum group from week 4 to week 8. Self-rated symptoms of depression reduced over time in both groups, but did so more so in the verum group than in the control group.; This double-blind, randomized, and placebo-controlled clinical trial showed that the administration of R. damascena oil ameliorates sexual dysfunction in male patients suffering from both MDD and SSRI-I SD. Further, the symptoms of depression reduced as sexual dysfunction improved

Emotionally Stable, Extraverted, Conscientious, and Unambivalent: Iranian Women Successfully Navigating Divorce Adjustment

The aim of the present study was to explore the extent to which the combination of the Big Five personality traits and adult attachment styles are associated with a broad array of divorce adjustment (DA) indicators. A total of 200 Iranian divorced women took part in the study. Participants completed a series of self-rating questionnaires covering socio-demographic, the Big Five, adult attachment styles, and indicators of DA. The results showed that higher levels of the Big Five (with neuroticism reverse-coded) were collectively associated with higher levels of feeling of self-worth, disentanglement of love relationships (DLRS), social self-worth, rebuilding of social trust, lower levels of symptoms of grief, and feelings of self-anger. Higher levels of secure attachment were associated with higher levels of self-worth and DLRS. Lower levels of ambivalent attachment were associated with higher levels of DLRs, rebuilding of social trust, and lower levels of grief symptoms and feeling of self-anger. The role of Iranian culture on post-DA is discussed