96 research outputs found

    Interviews with Charley King, Barbara Hall Maricle, Vern Kear, Sherry Smith, Elizabeth Stoskopt, Martha Margheim, Verna Schneider, Edith M. Hill, Master John Sackett, Rose Arnold, Olga Elizabeth Luschen Dennis, and Clarence Loredstsch

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    Interviews with Charley King, Barbara Hall Maricle, Vern Kear, Sherry Smith, Elizabeth Stoskopt, Martha Margheim, Verna Schneider, Edith M. Hill, Master John Sackett, Rose Arnold, Olga Elizabeth Luschen Dennis, and Clarence Loredstsch The first tape is missing. Content begins with the partial interview of Olga Elizabeth Luschen Dennis. 00:00:00 - Family in Russell County (partial) 00:01:02 - Meeting her husband for the first time 00:02:32 - Girlhood experiences and reminiscences 00:03:50 - Pre-recorded History of Fort Larned 00:07:04 - Unknown speaker, Kit Carson\u27s killing of a mule he mistook for an Indigenous American 00:10:46 - Buffalo Bill Cody 00:13:03 - Stories about the Kiowa 00:16:06 - Woodland Tribe in Pawnee County, KS 00:18:24 - Quivira Tribe in Pawnee County, KS 00:21:46 - Exhuming Indigenous remains in 1958 00:23:16 - Woodland Tribe pottery 00:27:32 - Dog skeleton 00:33:57 - Woodland Tribe weapons 00:35:42 - Woodland Tribe ornamentation 00:39:05 - Introduction to interview with Clarence Loredstsch by Louise Maxwell. This portion of the recording is muffled and difficult to understand. 00:39:43 - Fort Fletcher 00:45:30 - Graves and landmarkshttps://scholars.fhsu.edu/sackett/1054/thumbnail.jp

    Endothelial cell suppression of peripheral blood mononuclear cell trafficking in vitro during acute exposure to feline immunodeficiency virus

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    Trafficking of peripheral blood mononuclear cells (PBMCs) into the brain is a critical step in the initiation of human immunodeficiency virus (HIV)-associated central nervous system disease. To examine potential factors that control trafficking during the earliest stages of infection, PBMC transmigration across a cultured feline brain endothelial cell (BECs) monolayer was measured after selective exposure of various cell types to feline immunodeficiency virus (FIV). Infection of the PBMCs with FIV increased the trafficking of monocytes and CD4 and CD8 T cells. Additional exposure of the BECs to FIV suppressed mean monocyte, CD4 T cell, and CD8 T cell trafficking. B cell trafficking was unaltered by these changing conditions. Subsequent exposure of astrocytes or microglia to FIV altered transmigration of different PBMC subsets in different ways. Treated microglia compared with treated astrocytes decreased monocyte transmigration, whereas B cell transmigration was increased significantly. When both astrocytes and microglia were exposed to FIV, an increase in CD8 T cell transmigration relative to BECs alone, to BECs plus astrocytes, or to BECs plus microglia was demonstrated. Thus, initial exposure of PBMCs to FIV is sufficient to induce a general increase in trafficking, whereas initial exposure of endothelial cells to FIV tends to down-regulate this effect. Selectivity of trafficking of specific PBMC subsets is apparent only after exposure of cells of the central nervous system to FIV in co-culture with the endothelium

    Compartmentalization and evolution of feline immunodeficiency virus between the central nervous system and periphery following intracerebroventricular or systemic inoculation

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    The emergence of distinct neuropathogenic strains resulting from the adaptation and the unique evolution of human immunodeficiency virus (HIV) in the brain may contribute to the development of HIV-induced neurological diseases. In this study, the authors tracked early changes in virus evolution and compartmentalization between peripheral tissues and the central nervous system (CNS) after intracerebroventricular (i.c.v.) or intraperitoneal (i.p.) inoculation of animals with cell-free feline immunodeficiency virus (FIV). Using the FIV-NCSU1 envelope V3–V4 heteroduplex tracking assay (HTA), the authors observed a rapid compartmentalization of envelope variants between the CNS and periphery. Animals receiving the i.c.v. inoculation showed two peaks of viral RNA in the cerebrospinal fluid (CSF) with very different HTA patterns. Compared to the initial viral peak in CSF, the second peak showed an increased compartmentalization from plasma, reduced viral diversity, and more divergence from the proviral DNA in peripheral blood mononuclear cells (PBMCs) and the choroid plexus. In contrast, changes in plasma over the same time period were small. Different animals harbored different FIV DNA genotypes with varied regional compartmentalization within the brain. These results demonstrated that the virus within the CNS experienced a relatively independent but variable evolution from the periphery. Initial penetration of virus into the CSF facilitated the development of brain-specific reservoirs and viral diversification within the CNS

    Cerebrospinal fluid is an efficient route for establishing brain infection with feline immunodeficiency virus and transfering infectious virus to the periphery

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    Like human immunodeficiency virus (HIV), feline immunodeficiency virus (FIV) invades and infects the central nervous system (CNS) soon after peripheral infection. The appearance of viral RNA is particularly prominent in the cerebrospinal fluid (CSF), suggesting an efficient route of virus transfer across the blood-CSF barrier. This raises the concern whether this route can establish a stable viral reservoir and also be a source of virus capable of reseeding peripheral systems. To examine this possibility, 200 ÎĽl of cell-free NCSU1 FIV or FIV-infected choroid plexus macrophages (ChP-Mac) was directly injected into the right lateral ventricle of the brain. Negative controls were sham inoculated with uninfected ChP-Mac or virus-free culture supernatant and positive controls were infected systemically by intraperitoneal (i.p.) injection. Intracerebroventricular (i.c.v.) inoculation with cell-free FIV resulted in high levels of plasma FIV RNA detected as early as 1 to 2 weeks post inoculation in all cats. In each case, the plasma viremia preceded the detection of CSF viral RNA. Compared to i.p. cats, i.c.v. cats had 32-fold higher CSF viral loads, 8-fold higher ratios of CSF to plasma viral load, and a 23-fold greater content of FIV proviral DNA in the brain. No FIV RNA was detected in plasma or CSF from the cats inoculated with FIV-infected ChP-Mac but an acute inflammatory response and a slight suppression of the CD4+:CD8+ ratio were observed. These results indicate that free FIV circulating in the CSF promotes infection of the CNS and provides a highly efficient pathway for the transfer of infectious virus to the periphery

    Book reviews

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    Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/45645/1/11199_2004_Article_BF00287975.pd

    Newsletter Networks in the Feminist History and Archives Movement

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    This article examines how networks have been critical to the construction of feminist histories. The author examines the publication Matrices: A Lesbian/Feminist Research Newsletter (1977–1996), to argue that a feminist network mode can be traced through the examination of small-scale print newsletters that draw on the language and function of networks. Publications such as Matrices emerge into wide production and circulation in the 1970s alongside feminist community archives, and newsletters and archives work together as interconnected social movement technologies. Newsletters enabled activist-researchers writing feminist histories to share difficult-to-access information, resources, and primary sources via photocopying and other modes of print reproduction.  Looking from the present, the author examines how network thinking has been a feature of feminist activism and knowledge production since before the Internet, suggesting that publications such as Matrices are part of a longer history of networked communications media in feminist contexts

    IMAP: Integral Self-awareness Mapping Process—a study to evolve a method for consciousness development

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    This author’s concept of an Integral Self-Awareness Mapping Process (IMAP) was studied through the experiences of 7 participants over a 3 month period. The IMAP process involved ten self-reflection steps in an interactive, weekly, web-based community discussion forum. The outcomes of the case study indicate a partial validation of the original purpose and philosophy associated with developing one’s integral consciousness : to inspire processes of observing, balancing, and integrating dimensions of Self and consciousness in the unique ways we each require on our evolutionary journey. While most participants realized some value from the IMAP experience, they also identified shortcomings in the design with 2 participants expressing strong disagreement with the integral philosophy and developmental principles embodied by IMAP. Building upon participant feedback, additional literature reviews, and experiences with alternative models, systems, and practices for consciousness development, this researcher identified significant opportunities for design improvement. A central finding was the correlation between developmental motivation and belief in one’s Higher Self, Essence-being, or Soul as individual agent of change and consciousness evolution. The revised model and process of consciousness development, renamed I-MAP, incorporates key insights from Aurobindo (1993), Ouspensky (1950/1981), Ichazo (1991), Stevens (1989/1994a), and Young (1976/1999) including additional essence and personality attributes for self-discernment by participants. While the original model located the subjective singular perspective of awareness in one of four quadrants, I-MAP shifts the singular-subjective perspective to the central axis of a torus shaped model that delineates seven qualities of consciousness correlating with seven developmental stages. Relative to the Integral Life Practice program developed by Wilber, Patten, Leonard, and Morelli (2008), the I-MAP program proposes a comprehensive resource for participant understanding of unique essence and personality features in order to accelerate development of each individual’s consciousness and capacity to contribute to collective evolution

    The structure of intellect : its interpratation and uses/ Meeker

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    xix, 203 hal.: ill.; 23 cm

    Influence of actuator geometry on rotating losses in heteropolar magnetic bearings

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    Recently, work on rotating losses in magnetic bearings has focused mainly on the measurement of rotating losses, and on the creation of models that attempt to reproduce these results. Though there has been some success on both counts, there has been less emphasis on interpreting what these results mean in terms of practical guidelines for the design of low-loss bearings. The present work reformulates a previously developed analytical model of rotating loss so that the effects shaft speed and pole count on rotating losses can be more easily identified. Conclusions drawn from this formulation are then compared to previously reported experimental data
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