Isolation of ntrA-like mutants of Azobacter vinelandii

A number of of chlorate-resistant mutants of Azotobacter vinelandii affected in a general control of nitrogen metabolism were isolated. These mutants could not utilize dinitrogen, nitrate, or nitrite as a nitrogen source. The reason for this inability is that they were simultaneously deficient in nitrogenase and nitrate and nitrite reductase activities. They were complemented by a cosmid carrying a DNA fragment of A. vinelandii able to complement ntrA mutants of Escherichia coli, so they seemed to be ntrA-like mutants.Comisión Asesora Científica y Técnica 302

Las colinesterasas del suero humano.

La farmacogenética nace y se desarrolla con el descubrimiento de que, en muchas ocasiones, tales diferencias en la respuesta a los fármacos son hereditarias