Clinical And Neuropsychological Correlation In Patients With Rolandic Epilepsy [correlação Entre Achados Clínicos E Neuropsicológicos Em Pacientes Com Epilepsia Rolândica]

Objectives: To evaluate the presence of neurological soft signs (NSS) and to correlate them with the Wechsler Intelligence Scale for Children (WISC III) in patients with rolandic epilepsy (RE). Methods: Forty children and adolescents aged between 9 and 15 years were studied. They were divided into two groups: G1 - patients with RE (n=20) - and G2 - healthy controls without epilepsy (n=20). They were assessed with the Quick Neurological Screening Test (QNST II) - clinical trial to search for NSS -, and the WISC III - neuropsychological test. Results: No statistical difference between groups was found in WISC III and QNST II. However, children with poorer motor skills had worse performance in the QNST II and also in the execution intelligence quotient - IQ (p=0.001) and in total IQ (p=0.004), thus showing a positive correlation between them. Conclusions: The QNST II is a good screening tool for the neurologist to detect abnormalities in fine motor skills.709691693Berg, A.T., Berkovic, S.F., Brodie, M.J., Revised terminology and concepts for organization of seizures and epilepsies: Report of the ILAE Commission on Classification and Terminology, 2005-2009 (2010) Epilepsia, 51, pp. 676-685Lerman, P., Kivity, S., Benign focal epilepsy of childhood. A follow-up study of 100 recovered patients (1975) Arch Neurol, 32, pp. 261-264Bouma, P.A., Bovenkerk, A.C., Westendorp, R.G., Brouwer, O.F., The course of benign partial epilepsy of childhood with centrotemporal spikes: A meta-analysis (1997) Neurology, 48 (2), pp. 430-437Hommet, C., Billard, C., Motte, J., Cognitive function in adolescents and young adults in complete remission from benign childhood epilepsy with centro-temporal spikes (2001) Epileptic Disord, 3, pp. 207-216D'Alessandro, P., Piccirilli, M., Tiacci, C., Neuropsychological features of benign partial epilepsy in children (1990) Ital J Neurol Sci, 11, pp. 265-269Binnie, C.D., Marston, D., Cognitive correlates of interictal discharges (1992) Epilepsia, 33 (SUPPL. 6), pp. S11-S17Fonseca, L.C., Tedrus, G.M., Pacheco, E.M., Epileptiform EEG discharges in benign childhood epilepsy with centrotemporal spikes: Reactivity and transitory cognitive impairment (2007) Epilepsy Behav, 11, pp. 65-70Baglietto, M.G., Battaglia, F.M., Nobili, N., Neuropsychological disorders related to interictal epileptic discharges during sleep in benign epilepsy of childhood with centrotemporal or rolandic spikes (2001) Dev Med Child Neurol, 43, pp. 407-412Hermann, B.P., Jones, J., Sheth, R., Seidenberg, M., Cognitive and magnetic resonance volumetric abnormalities in new-onset pediatric epilepsy (2007) Semin Pediatri Neurol, 14, pp. 173-180Panayiotopoulos, C.P., Benign childhood partial epilepsies: Benign childhood seizures susceptibility syndromes (1993) J Neurol Neurosurg Psychiatry, 56, pp. 2-5Lindgren, A., Kihlgren, M., Melin, L., Croona, C., Development of cognitive functions in children with rolandic epilepsy (2004) Epilepsy Behav, 5, pp. 903-910Weglage, J., Demsky, A., Pietsh, M., Kurlemann, G., Neuropsychological, intellectual, and behavioral findings in patients with centrotemporal spikes with and without seizure (1997) Dev Med Child Neurol, 39, pp. 645-651Deonna, T., Rolandic epilepsy: Neuropsychology of the active epilepsy phase (2000) Epileptic Disord, 2 (SUPPL. 1), pp. S59-S61Deonna, T., Zesiger, P., Davidoff, V., Benign partial epilepsy of childhood: A longitudinal neuropsychological and EEG study of cognitive function (2000) Dev Med Child Neurol, 42, pp. 595-60