3 research outputs found
Catalytic Hydrotrifluoromethylation of Unactivated Alkenes
A visible-light-mediated hydrotrifluoromethylation of
unactivated
alkenes that uses the Umemoto reagent as the CF<sub>3</sub> source
and MeOH as the reductant is disclosed. This effective transformation
operates at room temperature in the presence of 5 mol % RuĀ(bpy)<sub>3</sub>Cl<sub>2</sub>; the process is characterized by its operational
simplicity and functional group tolerance
Trifluoromethylation of Allylsilanes under Photoredox Catalysis
A new catalytic method to access allylic secondary CF<sub>3</sub> products is described. These reactions use the visible light excited Ru(bpy)<sub>3</sub>Cl<sub>2</sub>Ā·6H<sub>2</sub>O catalyst and the Togni or Umemoto reagent as the CF<sub>3</sub> source. The photoredox catalytic manifold delivers enantioenriched allylic trifluoromethylated products not accessible under Cu(I) catalysis