381 research outputs found
Black holes admitting a Freudenthal dual
The quantised charges x of four dimensional stringy black holes may be
assigned to elements of an integral Freudenthal triple system whose
automorphism group is the corresponding U-duality and whose U-invariant quartic
norm Delta(x) determines the lowest order entropy. Here we introduce a
Freudenthal duality x -> \tilde{x}, for which \tilde{\tilde{x}}=-x. Although
distinct from U-duality it nevertheless leaves Delta(x) invariant. However, the
requirement that \tilde{x} be integer restricts us to the subset of black holes
for which Delta(x) is necessarily a perfect square. The issue of higher-order
corrections remains open as some, but not all, of the discrete U-duality
invariants are Freudenthal invariant. Similarly, the quantised charges A of
five dimensional black holes and strings may be assigned to elements of an
integral Jordan algebra, whose cubic norm N(A) determines the lowest order
entropy. We introduce an analogous Jordan dual A*, with N(A) necessarily a
perfect cube, for which A**=A and which leaves N(A) invariant. The two
dualities are related by a 4D/5D lift.Comment: 32 pages revtex, 10 tables; minor corrections, references adde
Body Mass Index's influence on arterial hypertension in Type 1 diabetes - A brief report from IMI-SOPHIA study
Information on BMI and risk of developing hypertension in type 1 diabetes (T1D) is scarce, and it comes mostly from cross-sectional analyses. This study underscores a risk of developing hypertension in T1D individuals with high BMI, and this risk appears to be higher than in those with type 2 diabetes.</p
Body Mass Index's influence on arterial hypertension in Type 1 diabetes - A brief report from IMI-SOPHIA study
Information on BMI and risk of developing hypertension in type 1 diabetes (T1D) is scarce, and it comes mostly from cross-sectional analyses. This study underscores a risk of developing hypertension in T1D individuals with high BMI, and this risk appears to be higher than in those with type 2 diabetes.</p
Socio-economic status and mortality in people with type 1 diabetes in Scotland 2006-2015:a retrospective cohort study
Three fermions with six single particle states can be entangled in two inequivalent ways
Using a generalization of Cayley's hyperdeterminant as a new measure of
tripartite fermionic entanglement we obtain the SLOCC classification of
three-fermion systems with six single particle states. A special subclass of
such three-fermion systems is shown to have the same properties as the
well-known three-qubit ones. Our results can be presented in a unified way
using Freudenthal triple systems based on cubic Jordan algebras. For systems
with an arbitrary number of fermions and single particle states we propose the
Pl\"ucker relations as a sufficient and necessary condition of separability.Comment: 23 pages LATE
High intensity exercise as a dishabituating stimulus restores counterregulatory responses in recurrently hypoglycemic rodents
Hypoglycemia is a major adverse effect of insulin therapy for people with type 1 diabetes (T1D). Profound defects in the normal counterregulatory response to hypoglycemia explain the frequency of hypoglycemia occurrence in T1D. Defective counterregulation results to a large extent from prior exposure to hypoglycemia per se, leading to a condition called impaired awareness of hypoglycemia (IAH), the cause of which is unknown. In the current study, we investigate the hypothesis that IAH develops through a special type of adaptive memory referred to as habituation. To test this hypothesis, we used a novel intense stimulus (high-intensity exercise) to demonstrate two classic features of a habituated response, namely dishabituation and response recovery. We demonstrate that after recurrent hypoglycemia the introduction of a novel dishabituating stimulus (a single burst of high-intensity exercise) in male Sprague-Dawley rats restores the defective hypoglycemia counterregulatory response. In addition, the rats showed an enhanced response to the novel stimulus (response recovery). We make the further observation using proteomic analysis of hypothalamic extracts that high-intensity exercise in recurrently hypoglycemic rats increases levels of a number of proteins linked with brain-derived neurotrophic factor signaling. These findings may lead to novel therapeutic approaches for individuals with T1D and IAH.</jats:p
Renal and Cardiovascular Effects of SGLT2 inhibition in combination with loop Diuretics in patients with Type 2 Diabetes and Chronic Heart Failure:The RECEDE-CHF Trial
Cardiovascular disease prevalence and risk factor prevalence in Type 2 diabetes:a contemporary analysis
Is there a Jordan geometry underlying quantum physics?
There have been several propositions for a geometric and essentially
non-linear formulation of quantum mechanics. From a purely mathematical point
of view, the point of view of Jordan algebra theory might give new strength to
such approaches: there is a ``Jordan geometry'' belonging to the Jordan part of
the algebra of observables, in the same way as Lie groups belong to the Lie
part. Both the Lie geometry and the Jordan geometry are well-adapted to
describe certain features of quantum theory. We concentrate here on the
mathematical description of the Jordan geometry and raise some questions
concerning possible relations with foundational issues of quantum theory.Comment: 30 page
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