4,777 research outputs found
Method and apparatus for holding two separate metal pieces together for welding
A method of holding two separate metal pieces together for welding is described including the steps of overlapping a portion of one of the metal pieces on a portion of the other metal piece, encasing the overlapping metal piece in a compressible device, drawing the compressible device into an enclosure, and compressing a portion of the compressible device around the overlapping portions of the metal pieces for holding the metal pieces under constant and equal pressure during welding. The preferred apparatus for performing the method utilizes a support mechanism to support the two separate metal pieces in an overlapping configuration; a compressible device surrounding the support mechanism and at least one of the metal pieces, and a compressing device surrounding the compressible device for compressing the compressible device around the overlapping portions of the metal pieces, thus providing constant and equal pressure at all points on the overlapping portions of the metal pieces
Tissue stimulator enclosure welding fixture
It was demonstrated that the thickness of the stimulator titanium enclosure is directly related to the battery recharge time cycle. Reduction of the titanium enclosure thickness from approximately 0.37 mm (0.015 inch) to 0.05 mm (0.002 inch) significantly reduced the recharge time cycle and thereby patient inconvenience. However, fabrication of titanium enclosures from the thinner material introduced problems in forming, holding, and welding that required improvement in state of the art shop practices. The procedures that were utilized to resolve these fabrication problems are described
Glycophenotype of prostatic carcinomas.
The factors that affect the progression of prostatic carcinoma are poorly understood, but it is known that carbohydrate antigens on the tumour cell surface play a role in the transforming and metastatic processes. The present report aimed to perform a comparative, lectin-histochemical study of benign and carcinomatous prostates, using a battery of lectins, in combination with monoclonal antibodies against Lewis antigens, and a semi quantitative study, to investigate the changes in glycosylation patterns that occur in prostatic carcinoma. Blocks from 27 necropsy cases of prostatic carcinoma were sectioned and stained with H+E, fifteen biotinylated lectins chosen to probe for a wide range of oligosaccharide sequences within several categories of glycoprotein glycans, using a lectin-biotin avidin-peroxidase method, and monoclonal antibodies against Lewisa, sialyl Lewisa and sialyl Lewisx antigens. The glycophenotype of prostatic carcinoma differed from that of the noncancerous prostate in revealing more intense staining with the following lectins (AAA, UEA-1, DBA, WFA, VVA, HPA, BSA-1B4, MPA, ECA, AHA, and CTA), while the binding patterns of (GNA and NPA) were almost similar in both prostatic carcinoma and the noncancerous prostate. Lewis antigens are found to be expressed in prostatic carcinomas but not in the noncancerous prostate. The observations of this study suggest that the gylcophenotype of transformed prostatic cells was modified. It showed a moderate increase in, and changing patterns of, fucosylation and galactosylation, increased branching of side chains and sharp rise in 2 deoxy, 2 acetamido galactosylation and masking process by sialylation, especially by ĂÄ
2-3 and ĂÄ
2-6 linkages. All these changes in the glycosylation pattern of the transformed prostatic cells were observed on O-glycans, no changes were observed on N-glycans
1420 MHz Continuum Absorption Towards Extragalactic Sources in the Galactic Plane
We present a 21-cm emission-absorption study towards extragalactic sources in
the Canadian Galactic Plane Survey (CGPS). We have analyzed HI spectra towards
437 sources with S > 150 mJy, giving us a source density of 0.6 sources per
square degree at arcminute resolution. We present the results of a first
analysis of the HI temperatures, densities, and feature statistics. Particular
emphasis is placed on 5 features with observed spin temperatures below 40 K. We
find most spin temperatures in the range from 40 K to 300 K. A simple HI
two-component model constrains the bulk of the cold component to temperatures
(T_c) between 40 K and 100 K. T_c peaks in the Perseus arm region and clearly
drops off with Galactocentric radius, R, beyond that. The HI density follows
this trend, ranging from a local value of 0.4 cm^{-3} to less than 0.1 cm^{-3}
at R = 20 kpc. We find that HI emission alone on average traces about 75% of
the total HI column density, as compared to the total inferred by the emission
and absorption. Comparing the neutral hydrogen absorption to CO emission no
correlation is found in general, but all strong CO emission is accompanied by a
visible HI spectral feature. Finally, the number of spectral HI absorption
features per kpc drop off exponentially with increasing R.Comment: 13 pages, 13 figures, Accepted for March 2004 Ap
Statistical Model Selection for TID Hardness Assurance
Radiation Hardness Assurance (RHA) methodologies against Total Ionizing Dose (TID) degradation impose rigorous statistical treatments for data from a part's Radiation Lot Acceptance Test (RLAT) and/or its historical performance. However, no similar methods exist for using "similarity" data - that is, data for similar parts fabricated in the same process as the part under qualification. This is despite the greater difficulty and potential risk in interpreting of similarity data. In this work, we develop methods to disentangle part-to-part, lot-to-lot and part-type-to-part-type variation. The methods we develop apply not just for qualification decisions, but also for quality control and detection of process changes and other "out-of-family" behavior. We begin by discussing the data used in the study and the challenges of developing a statistic providing a meaningful measure of degradation across multiple part types, each with its own performance specifications. We then develop analysis techniques and apply them to the different data sets
The distance and neutral environment of the massive stellar cluster Westerlund 1
The goal of this study is to determine a distance to Westerlund 1 independent
of the characteristics of the stellar population and to study its neutral
environment, using observations of atomic hydrogen. The HI observations are
taken from the Southern Galactic Plane Survey to study HI absorption in the
direction of the HII region created by the members of Westerlund 1 and to
investigate its environment as observed in the HI line emission. A Galactic
rotation curve was derived using the recently revised values for the Galactic
centre distance of kpc, and the velocity of the Sun around the
Galactic centre of km s. The newly determined
rotation model leads us to derive a distance of kpc to Westerlund
1, consistent with a location in the Scutum-Crux Arm. Included in this estimate
is a very careful investigation of possible sources of error for the Galactic
rotation curve. We also report on small expanding HI features around the
cluster with a maximum dynamic age of 600,000 years and a larger bubble which
has a minimum dynamic age of 2.5 million years. Additionally we re-calculated
the kinematic distances to nearby HII regions and supernova remnants based on
our new Galaxic rotation curve. We propose that in the early stages of the
development of Wd 1 a large interstellar bubble of diameter about 50 pc was
created by the cluster members. This bubble has a dynamic age similar to the
age of the cluster. Small expanding bubbles, with dynamical ages Myr
are found around Wd 1, which we suggest consist of recombined material lost by
cluster members through their winds.Comment: 8 pages, accepted for publication in A&
Electronic states and Landau levels in graphene stacks
We analyze, within a minimal model that allows analytical calculations, the
electronic structure and Landau levels of graphene multi-layers with different
stacking orders. We find, among other results, that electrostatic effects can
induce a strongly divergent density of states in bi- and tri-layers,
reminiscent of one-dimensional systems. The density of states at the surface of
semi-infinite stacks, on the other hand, may vanish at low energies, or show a
band of surface states, depending on the stacking order
The Galactic Distribution of Large HI Shells
We report the discovery of nineteen new HI shells in the Southern Galactic
Plane Survey (SGPS). These shells, which range in radius from 40 pc to 1 kpc,
were found in the low resolution Parkes portion of the SGPS dataset, covering
Galactic longitudes l=253 deg to l=358 deg. Here we give the properties of
individual shells, including positions, physical dimensions, energetics,
masses, and possible associations. We also examine the distribution of these
shells in the Milky Way and find that several of the shells are located between
the spiral arms of the Galaxy. We offer possible explanations for this effect,
in particular that the density gradient away from spiral arms, combined with
the many generations of sequential star formation required to create large
shells, could lead to a preferential placement of shells on the trailing edges
of spiral arms. Spiral density wave theory is used in order to derive the
magnitude of the density gradient behind spiral arms. We find that the density
gradient away from spiral arms is comparable to that out of the Galactic plane
and therefore suggest that this may lead to exaggerated shell expansion away
from spiral arms and into interarm regions.Comment: 25 pages, 20 embedded EPS figures, uses emulateapj.sty, to appear in
the Astrophysical Journa
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