Long-Term Measurements of Ground Motions Offshore

Long-Term measurements of earthquake ground motions offshore, using the Sandia National Laboratories\u27 SEMS device which records only the strongest motions and transmits them upon command to a boat at the surface, have shown that offshore ground motions may in certain cases be substantially different from empirically predicted ground motions based on onshore data. In particular, the attenuation effects of soft and/or gassy soils, the wedging of offshore deposits as a function of direction to and distance from the source, and sharp velocity-depth profiles, are shown to be possible actors contributing to such differences. For the well constrained recording to date, the offshore ground motions are only 13 to 23 percent of those which would be calculated using empirical predictions based on onshore data. To address this situation, Sandia has installed a net of three long-lived (SEMS), two of them in the vicinity of instrumented platforms, in the Sandia Barbara Channel. The results are intended to evaluate the earthquake hazards of offshore energy developments and to provide firm data on the design parameters required for the harvesting of 0ffshore energy resources

Limiting Swine Stress with Evaporative Cooling in the Southeast

Three-hourly weather data for 7 locations in the Southeast and Central United States were used to evaluate the feasibility of evaporative cooling for reducing swine stress. Stress was defined as a relationship between dry and wet bulb temperatures which exceeded a stress index of 85. This analysis indicates that properly installed evaporative coolers could reduce the number of hours that stress would occur in swine facilities from 89.6 to 96.4% depending on location

Limiting Swine Stress with Evaporative Cooling in Kentucky

During the summer, temperatures in swine buildings often rise to levels that adversely affect animal performance and the profitability of these operations. Heat stress reduces reproductive efficiency in the breeding herd, affecting both the boar and sow. During extended hot weather periods, death of farrowing sows may result

Performance of an Evaporative Cooling System in a Gestation House

This field study was conducted to determine the effectiveness of an evaporative pad cooler for modifying the environment in a gestation house in Kentucky and to compare the measured results with the calculated performance of evaporative cooling systems. The building used in the study was a 68-crate gestation house, as described in Figure 1. The building was oriented east-west and was well insulated. There were no windows in the facility. It was fully occupied, throughout the study, with sows with an average weight of 350 lbs. A negative pressure system was used to ventilate the building with a 36 single-speed exhaust fan located in the east end wall (Figure 1). A 4\u27 x 12\u27 evaporative pad was located in the west end wall adjacent to the air intake. Shutters were mounted on the outside of the building to provide shade for the pads and to protect them during inclement weather

Patient specific modeling of palpation-based prostate cancer diagnosis: effects of pelvic cavity anatomy and intrabladder pressure.

Computational modeling has become a successful tool for scientific advances including understanding the behavior of biological and biomedical systems as well as improving clinical practice. In most cases, only general models are used without taking into account patient-specific features. However, patient specificity has proven to be crucial in guiding clinical practice because of disastrous consequences that can arise should the model be inaccurate. This paper proposes a framework for the computational modeling applied to the example of the male pelvic cavity for the purpose of prostate cancer diagnostics using palpation. The effects of patient specific structural features on palpation response are studied in three selected patients with very different pathophysiological conditions whose pelvic cavities are reconstructed from MRI scans. In particular, the role of intrabladder pressure in the outcome of digital rectal examination is investigated with the objective of providing guidelines to practitioners to enhance the effectiveness of diagnosis. Furthermore, the presence of the pelvic bone in the model is assessed to determine the pathophysiological conditions in which it has to be modeled. The conclusions and suggestions of this work have potential use not only in clinical practice and also for biomechanical modeling where structural patient-specificity needs to be considered. © 2015 The Authors. International Journal for Numerical Methods in Biomedical Engineering published by John Wiley & Sons Ltd

The Texas Community-Engagement Research Alliance Against COVID-19 in Disproportionately Affected Communities (TX CEAL) Consortium

The coronavirus disease 2019 (COVID-19) pandemic requires urgent implementation of effective community-engaged strategies to enhance education, awareness, and inclusion of underserved communities in prevention, mitigation, and treatment efforts. The Texas Community-Engagement Alliance Consortium was established with support from the United States’ National Institutes of Health (NIH) to conduct community-engaged projects in selected geographic locations with a high proportion of medically underserved minority groups with a disproportionate burden of COVID-19 disease and hospitalizations. The purpose of this paper is to describe the development of the Consortium. The Consortium organized seven projects with focused activities to address COVID-19 clinical and vaccine trials in highly affected counties, as well as critical statewide efforts. Five Texas counties (Bexar, Dallas, Harris, Hidalgo, and Tarrant) were chosen by NIH because of high concentrations of underserved minority communities, existing community infrastructure, ongoing efforts against COVID-19, and disproportionate burden of COVID-19. Policies and practices can contribute to disparities in COVID-19 risk, morbidity, and mortality. Community engagement is an essential element for effective public health strategies in medically underserved minority areas. Working with partners, the Consortium will use community engagement strategies to address COVID-19 disparities

Quantitative mechanical assessment of the whole prostate gland ex vivo using dynamic instrumented palpation

An instrumented palpation sensor, designed for measuring the dynamic modulus of tissue in vivo, has been developed and trialled on ex vivo whole prostate glands. The sensor consists of a flexible membrane sensor/actuator with an embedded strain gauge and is actuated using a dynamically varying airflow at frequencies of 1 and 5 Hz. The device was calibrated using an indentation stiffness measurement rig and gelatine samples with a range of static modulus similar to that reported in the literature for prostate tissue. The glands were removed from patients with diagnosed prostate cancer scheduled for radical prostatectomy, and the stiffness was measured within 30 min of surgical removal. Each prostate was later examined histologically in a column immediately below each indentation point and graded into one of the four groups; normal, benign prostatic hyperplasia, cancerous and mixed cancer and benign prostatic hyperplasia. In total, 11 prostates were assessed using multiple point probing, and the complex modulus at 1 and 5 Hz was calculated on a point-by-point basis. The device yielded values of quasi-static modulus of 15 ± 0.5 kPa and dynamic modulus of 20 ± 0.5 kPa for whole prostates, and a sensitivity of up to 80% with slightly lower specificity was achieved on diagnosis of prostate cancer using a combination of mechanical measures. This assessment did not take into account some obvious factors such as edge effects, overlap and clinical significance of the cancer, all of which would improve performance. The device, as currently configured, is immediately deployable in vivo. A number of improvements are also identified which could improve the sensitivity and specificity in future embodiments of the probe

Implementation of the Texas Community-Engaged Statewide Consortium for the Prevention of COVID-19

The Community Engagement Alliance (CEAL) Against COVID-19 Disparities aims to conduct community-engaged research and outreach. This paper describes the Texas CEAL Consortium\u27s activities in the first year and evaluates progress. The Texas CEAL Consortium comprised seven projects. To evaluate the Texas CEAL Consortium\u27s progress, we used components of the RE-AIM Framework. Evaluation included estimating the number of people reached for data collection and education activities (reach), individual project goals and progress (effectiveness), partnerships established and partner engagement (adoption), and outreach and education activities (implementation). During the one-year period, focus groups were conducted with 172 people and surveys with 2107 people across Texas. Partners represented various types of organizations, including 11 non-profit organizations, 4 academic institutions, 3 civic groups, 3 government agencies, 2 grassroots organizations, 2 faith-based organizations, 1 clinic, and 4 that were of other types. The main facets of implementation consisted of education activities and the development of trainings. Key recommendations for future consortiums relate to funding and research logistics and the value of strong community partnerships. The lessons learned in this first year of rapid deployment inform ongoing work by the Texas CEAL Consortium and future community-engaged projects