41 research outputs found

    The Upper Devonian Sandstone aquifer of Fife

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    The Devonian sandstone aquifer of Fife has long been recognised as one of the most important hydrogeological units in Scotland. Its importance was first acknowledged by Earp and Eden (1961), and the aquifer was later described by Foster et al (1976). Data were subsequently gathered together in map form (BGS, 1986) but little analysis of the aquifer was carried out other than a dissertation prepared by Barker (1981), occasional reports on specific issues such as nitrate pollution (e.g. Frost and Sargent, 1993; MacDonald, 1993; Ball, 1994), and the preparation of the 1: 100 000 scale Aquifer Vulnerability Map of Fife (SEPA, 1999). The aquifer currently supplies some 20 Ml/d during the winter, rising to 40 Ml/d in the summer months, when irrigation boreholes are put into use. Groundwater provides an important back up to public water supplies, particularly during dry years when river abstraction is restricted. Despite this, relatively little is known about the overall renewable resource potential of the aquifer. It is also only in recent years that means of safeguarding groundwater from pollution have been investigated in any detail. Renewed interest in the aquifer is now being driven on two fronts. The first is that the East of Scotland Water Authority (ESWA) needs to expand its source provision due to increasing demand. The second is that the Scottish Environment Protection Agency (SEPA) needs to look more closely at the aquifer potential if in the future groundwater abstraction licensing is introduced in significant aquifers (Robins and Ball, 1998). In addition, the requirements of the proposed EU Water Framework Directive indicate that a greater understanding of the aquifer and the sources it supplies will be needed in order to implement properly integrated surface and groundwater management on a catchment basis. With these goals in mind, the East of Scotland Water Authority, Scottish Environment Protection Agency and NERC have jointly commissioned this preliminary study of the Eden valley aquifer

    Post-acute COVID-19 neuropsychiatric symptoms are not associated with ongoing nervous system injury

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    A proportion of patients infected with severe acute respiratory syndrome coronavirus 2 experience a range of neuropsychiatric symptoms months after infection, including cognitive deficits, depression and anxiety. The mechanisms underpinning such symptoms remain elusive. Recent research has demonstrated that nervous system injury can occur during COVID-19. Whether ongoing neural injury in the months after COVID-19 accounts for the ongoing or emergent neuropsychiatric symptoms is unclear. Within a large prospective cohort study of adult survivors who were hospitalized for severe acute respiratory syndrome coronavirus 2 infection, we analysed plasma markers of nervous system injury and astrocytic activation, measured 6 months post-infection: neurofilament light, glial fibrillary acidic protein and total tau protein. We assessed whether these markers were associated with the severity of the acute COVID-19 illness and with post-acute neuropsychiatric symptoms (as measured by the Patient Health Questionnaire for depression, the General Anxiety Disorder assessment for anxiety, the Montreal Cognitive Assessment for objective cognitive deficit and the cognitive items of the Patient Symptom Questionnaire for subjective cognitive deficit) at 6 months and 1 year post-hospital discharge from COVID-19. No robust associations were found between markers of nervous system injury and severity of acute COVID-19 (except for an association of small effect size between duration of admission and neurofilament light) nor with post-acute neuropsychiatric symptoms. These results suggest that ongoing neuropsychiatric symptoms are not due to ongoing neural injury
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