819 research outputs found
Identifying the grain of barley varieties in Western Australia
THE identification of varieties of plants depends on the existence of a number of visual characters which have recognisably different forms in different varieties, but are relatively unaffected by environmental conditions.
For many species the characters of the whole plant may be required to arrive at a satisfactory identification and seed must be grown and the resulting plants compared with known varieties
Bussell barley
BUSSELL is a new high yielding 2-row barley variety named early in 1967.
An early maturing variety, with white grains of good quality, Bussell has short and extremely strong straw.
It has yielded more than any other variety under test in areas of Western Australia which receive more than 18 inches of annual rainfall.
It has yielded more than Prior in all areas
Probing the ground state in gauge theories
We consider two very different models of the flux tube linking two heavy
quarks: a string linking the matter fields and a Coulombic description of two
separately gauge invariant charges. We compare how close they are to the
unknown true ground state in compact U(1) and the SU(2) Higgs model.
Simulations in compact U(1) show that the string description is better in the
confined phase but the Coulombic description is best in the deconfined phase;
the last result is shown to agree with analytical calculations. Surprisingly in
the non-abelian theory the Coulombic description is better in both the Higgs
and confined phases. This indicates a significant difference in the width of
the flux tubes in the two theories.Comment: 13 pages, 10 .eps figures. V2: conclusions extende
Spin Polarization and Magneto-Coulomb Oscillations in Ferromagnetic Single Electron Devices
The magneto-Coulomb oscillation, the single electron repopulation induced by
external magnetic field, observed in a ferromagnetic single electron transistor
is further examined in various ferromagnetic single electron devices. In case
of double- and triple-junction devices made of Ni and Co electrodes, the single
electron repopulation always occurs from Ni to Co electrodes with increasing a
magnetic field, irrespective of the configurations of the electrodes. The
period of the magneto-Coulomb oscillation is proportional to the single
electron charging energy. All these features are consistently explained by the
mechanism that the Zeeman effect induces changes of the Fermi energy of the
ferromagnetic metal having a non-zero spin polarizations. Experimentally
determined spin polarizations are negative for both Ni and Co and the magnitude
is larger for Ni than Co as expected from band calculations.Comment: 4 pages, 3 figures, uses jpsj.sty, submitted to J. Phys. Soc. Jp
Magneto-Coulomb Oscillation in Ferromagnetic Single Electron Transistors
The mechanism of the magneto-Coulomb oscillation in ferromagnetic single
electron transistors (SET's) is theoretically considered. Variations in the
chemical potentials of the conduction electrons in the ferromagnetic island
electrode and the ferromagnetic lead electrodes in magnetic fields cause
changes in the free energy of the island electrode of the SET. Experimental
results of the magneto-Coulomb oscillation in a Ni/Co/Ni ferromagnetic SET are
presented and discussed. Possible applications of this phenomenon are also
discussed.Comment: 24 pages Latex, 5 figures in GIF files, style files included. Revised
version: some errors are corrected and further discussions are added. To be
published in J. Phys. Soc. Jpn. Vol.67 (1998) No.
Asymptotic Dynamics in Quantum Field Theory
A crucial element of scattering theory and the LSZ reduction formula is the
assumption that the coupling vanishes at large times. This is known not to hold
for the theories of the Standard Model and in general such asymptotic dynamics
is not well understood. We give a description of asymptotic dynamics in field
theories which incorporates the important features of weak convergence and
physical boundary conditions. Applications to theories with three and four
point interactions are presented and the results are shown to be completely
consistent with the results of perturbation theory.Comment: 18 pages, 3 figure
A study of National Health Service management of chronic osteoarthritis and low back pain
AIM: To describe treatment and referral patterns and National Health Service resource use in patients with chronic pain associated with low back pain or osteoarthritis, from a Primary Care perspective. BACKGROUND: Osteoarthritis and low back pain are the two commonest debilitating causes of chronic pain, with high health and social costs, and particularly important in primary care. Understanding current practice and resource use in their management will inform health service and educational requirements and the design and optimisation of future care. METHOD: Multi-centre, retrospective, descriptive study of adults (⩾18 years) with chronic pain arising from low back pain or osteoarthritis, identified through primary care records. Five general practices in Scotland, England (two), Northern Ireland and Wales. All patients with a diagnosis of low back pain or osteoarthritis made on or before 01/09/2006 who had received three or more prescriptions for pain medication were identified and a sub-sample randomly selected then consented to an in-depth review of their medical records (n=264). Data on management of chronic pain were collected retrospectively from patients’ records for three years from diagnosis (‘newly diagnosed’ patients) or for the most recent three years (‘established’ patients). FINDINGS: Patients received a wide variety of pain medications with no overall common prescribing pattern. GP visits represented the majority of the resource use and ‘newly diagnosed’ patients were significantly more likely to visit their GP for pain management than ‘established’ patients. Although ‘newly diagnosed’ patients had more referrals outside the GP practice, the number of visits to secondary care for pain management was similar for both groups. CONCLUSION: This retrospective study confirmed the complexity of managing these causes of chronic pain and the associated high resource use. It provides an in-depth picture of prescribing and referral patterns and of resource use
Gauge Fixing and BFV Quantization
Nonsingularity conditions are established for the BFV gauge-fixing fermion
which are sufficient for it to lead to the correct path integral for a theory
with constraints canonically quantized in the BFV approach. The conditions
ensure that anticommutator of this fermion with the BRST charge regularises the
path integral by regularising the trace over non-physical states in each ghost
sector. The results are applied to the quantization of a system which has a
Gribov problem, using a non-standard form of the gauge-fixing fermion.Comment: 14 page
Synthetic DNA immunotherapy in biochemically relapsed prostate cancer
Background: INO-5150 (PSA and PSMA) +/- INO-9012 (IL-12), a synthetic DNA immunotherapy, was assessed for safety, immunogenicity and efficacy in biochemically recurrent prostate cancer patients (pts).
Methods: Phase I, open-label, multi-center study in the US included pts with rising PSA after surgery and/or RT, PSA doubling time (PSADT) \u3e3 months (mos), testosterone \u3e150 ng/dL and no concurrent ADT. Safety, immunogenicity and efficacy (PSA kinetics, PFS) were evaluated in 4 treatment arms of 15 pts each. Arms A: 2mg INO-5150, B: 8.5 mg INO-5150, C: 2mg INO-5150 + 1mg INO-9012 and D: 8.5mg INO-5150 + 1mg INO-9012. Pts received 4 IM doses of vaccine followed by electroporation on day 0, wks 3, 12 and 24 and were followed for 72 wks.
Results: 50/61 (82%) pts completed all visits and treatments were well tolerated with no safety concerns. Median PFS for overall population [N = 61, baseline (D0) PSADT range (mos) 1.5-217.1, median 9.8] and for a subset of pts with D0 PSADT ≤12mos (N = 36) has not yet been reached (FU 3-19 mos). 86% of pts with D0 PSADT ≤12 mos were progression free through 19mos FU. 27 out of 36 (75%) pts with D0 PSADT≤ 12 mos had disease stabilization at wks 27 evidenced by significant improvement in log2PSA change over time (slope) and PSADT from D0 (Slope=0.19 declined to 0.1, PSADT=5.3 improved to 10.1 mos, p = \u3c0.0001). This effect was maintained at wk 72 (Slope=0.09, PSADT=10.6, p = \u3c0.0001). Immunogenicity was observed in 77% (47/61) of pts by multiple immunologic assessments. Patient immunogenicity to INO-5150 as determined by CD38 and Perforin + CD8 T cell immune reactivity correlated with attenuated % PSA rise compared to pts without reactivity (p = 0.05, n = 50).
Conclusions: INO-5150 +/- INO-9012 was safe, well tolerated and immunogenic. Clinical efficacy was observed in the patients with D0 PSADT≤ 12 mos as evidenced by a significant dampening of log2PSA change over time and increased PSADT up to 72 weeks FU. Additional genomic analyses are ongoing to further elucidate the correlation of immunologic efficacy and clinical benefit. (NCT02514213)
Symmetry breaking, conformal geometry and gauge invariance
When the electroweak action is rewritten in terms of SU(2) gauge invariant
variables, the Higgs can be interpreted as a conformal metric factor. We show
that asymptotic flatness of the metric is required to avoid a Gribov problem:
without it, the new variables fail to be nonperturbatively gauge invariant. We
also clarify the relations between this approach and unitary gauge fixing, and
the existence of similar transformations in other gauge theories.Comment: 11 pages. Version 2: typos corrected, discussion of Elitzur's theorem
added. Version to appear in J.Phys.
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