7,489 research outputs found

    NOSS Altimeter Detailed Algorithm specifications

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    The details of the algorithms and data sets required for satellite radar altimeter data processing are documented in a form suitable for (1) development of the benchmark software and (2) coding the operational software. The algorithms reported in detail are those established for altimeter processing. The algorithms which required some additional development before documenting for production were only scoped. The algorithms are divided into two levels of processing. The first level converts the data to engineering units and applies corrections for instrument variations. The second level provides geophysical measurements derived from altimeter parameters for oceanographic users

    A supersonic three-dimensional code for flow over blunt bodies: Program documentation and test cases

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    The use of a computer code for the calculation of steady, supersonic, three dimensional, inviscid flow over blunt bodies is illustrated. Input and output are given and explained for two cases: a pointed code of 20 deg half angle at 15 deg angle of attack in a free stream with M sub infinite = 7, and a cone-ogive-cylinder at 10 deg angle of attack with M sub infinite = 2.86. A source listing of the computer code is provided

    The Gap Function Phi(k,w) for a Two-leg t-J Ladder and the Pairing Interaction

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    The gap function phi(k,omega), determined from a Lanczos calculation for a doped 2-leg t-J ladder, is used to provide insight into the spatial and temporal structure of the pairing interaction. It implies that this interaction is a local near-neighbor coupling which is retarded. The onset frequency of the interaction is set by the energy of an S=1 magnon-hole-pair and it is spread out over a frequency region of order the bandwith

    NOSS altimeter algorithm specifications

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    A description of all algorithms required for altimeter processing is given. Each description includes title, description, inputs/outputs, general algebraic sequences and data volume. All required input/output data files are described and the computer resources required for the entire altimeter processing system were estimated. The majority of the data processing requirements for any radar altimeter of the Seasat-1 type are scoped. Additions and deletions could be made for the specific altimeter products required by other projects

    Assessment of vitamin E status in patients with systemic inflammatory response syndrome: plasma, plasma corrected for lipids or red blood cell measurements?

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    <b>Background:</b> There is some evidence that the plasma vitamin E status is perturbed as part of systemic inflammatory response and correcting this with other plasma markers may not lead to reliable results. The aim of the present study was to examine the longitudinal inter-relationships between plasma and red blood cell vitamin α-tocopherol in patients with systemic inflammatory response syndrome. <b>Methods:</b> α-tocopherol concentrations were measured, by HPLC, in plasma and red blood cells in normal subjects (n = 67) and in critically ill patients with systemic inflammatory response syndrome (n = 82) on admission and on follow-up. <b>Results:</b> Plasma α-tocopherol was significantly lower in the critically ill patients compared with the controls (all p < 0.001) with 41% of patients having concentrations below the 95% confidence interval. In contrast, when corrected for cholesterol, α-tocopherol concentrations were significantly higher in the critically ill patients compared with the control group (p < 0.001, 27% above the 95% confidence interval) and when corrected for triglycerides, α-tocopherol concentrations were significantly lower in the critically ill patients compared with the control group (p < 0.001). Red blood cell α-tocopherol corrected for haemoglobin was similar (p = 0.852) in the critically ill patients compared with control subjects. The longitudinal measurements (n = 53) gave similar results. <b>Conclusions:</b> These results indicate that there is a discrepancy between vitamin E measurements in plasma, in plasma corrected for lipids and in red blood cells. Although the value of correcting vitamin E concentrations by lipids is well established in population studies, the present study indicates that such correction is unreliable in the presence of systemic inflammatory response syndrome and that vitamin E status should be assessed using red blood cell α-tocopherol measurement

    A global atlas of GEOS-3 significant waveheight data and comparison of the data with national buoy data

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    The accuracy of the GEOS-3 significant waveheight estimates compared with buoy measurements of significant waveheight were determined. A global atlas of the GEOS-3 significant waveheight estimates gathered is presented. The GEOS-3 significant waveheight estimation algorithm is derived by analyzing the return waveform characteristics of the altimeter. Convergence considerations are examined, the rationale for a smoothing technique is presented and the convergence characteristics of the smoothed estimate are discussed. The GEOS-3 data are selected for comparison with buoy measurements. The GEOS-3 significant waveheight estimates are assembled in the form of a global atlas of contour maps. Both high and low sea state contour maps are presented, and the data are displayed both by seasons and for the entire duration of the GEOS-3 mission

    Catalog of sea state and wind speed in the South Atlantic Bight

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    The GEOS 3 significant waveheight and ground wind speed estimation algorithms are derived and then applied to all GEOS 3 data in the South Atlantic Bight. The investigation area is divided into five geographical sectors and significant waveheight and wind speed histograms are presented in each sector by month and by season. In the discussion of the histograms, definite seasonal trends are identified and examined

    Non-Parametric Estimation of Copula Parameters: Testing for Time-Varying Correlation

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    The correlation structure of financial assets is a key input with regard to portfolio and risk management. In this paper, we propose a non-parametric estimation method for the time-varying copula parameter. This is achieved in two steps: first, displaying the marginal distributions of financial asset returns by applying the empirical distribution function; second, by implementing the local likelihood method to estimate the copula parameters. The method for obtaining the optimal bandwidth through a maximum pseudo likelihood function and a statistical test on whether the copula parameter is time-varying are also introduced. A simulation study is conducted to show that our method is superior to its contender. Finally, we verify the proposed estimation methodology and time-varying statistical test by analysing the dynamic linkages between the Shanghai, Shenzhen and Hong Kong stock markets

    Comparison of the prognostic value of measures of the tumor inflammatory cell infiltrate and tumor-associated stroma in patients with primary operable colorectal cancer

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    The aim of the present study was to compare the clinical utility of two measures of the inflammatory cell infiltrate - a H&E-based assessment of the generalised inflammatory cell infiltrate (the Klintrup-Mäkinen (KM) grade), and an immunohistochemistry-based assessment of combined CD3+ and CD8+ T-cell density (the “Immunoscore”), in conjunction with assessment of the tumor stroma percentage (TSP) in patients undergoing resection of stage I-III colorectal cancer (CRC). 246 patients were identified from a prospectively maintained database of CRC resections in a single surgical unit. Assessment of KM grade and TSP was performed using full H&E sections. CD3+ and CD8+ T-cell density was assessed on full sections and the Immunoscore calculated. KM grade and Immunoscore were strongly associated (P<0.001). KM grade stratified cancer-specific survival (CSS) from 88% to 66% (P=0.002) and Immunoscore from 93% to 61% (P<0.001). Immunoscore further stratified survival of patients independent of KM grade from 94% (high KM, Im4) to 60% (low KM, Im0/1). Furthermore, TSP stratified survival of patients with a weak inflammatory cell infiltrate (low KM: from 75% to 47%; Im0/1: from 71% to 38%, both P<0.001) but not those with a strong inflammatory infiltrate. On multivariate analysis, only Immunoscore (HR 0.44, P<0.001) and TSP (HR 2.04, P<0.001) were independently associated with CSS. These results suggest that the prognostic value of an immunohistochemistry-based assessment of the inflammatory cell infiltrate is superior to H&E-based assessment in patients undergoing resection of stage I-III CRC. Furthermore, assessment of the tumor-associated stroma, using TSP, further improves prediction of outcome
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