The use of tissue culture propagated bluetongue virus for complement fixation studies on sheep sera

The development of a complement-fixation test possessing broad specificity, in which tissue culture propagated virus is used as antigen, for studies on bluetongue in sheep is described.The articles have been scanned in colour with a HP Scanjet 5590; 300dpi. Adobe Acrobat XI Pro was used to OCR the text and also for the merging and conversion to the final presentation PDF-format

The cytopathogenic action of bluetongue virus on tissue cultures and its application to the detection of antibodies in the serum of sheep

Cytopathogenic activity by egg adapted strains of bluetongue virus for sheep kidney cells in culture, and the neutralization of this activity by homologous antiserum are described. The possible applications of this phenomenon to studies on various phases of bluetongue is discussed briefly. Reference is made to preliminary studies which indicate that the property of cytopathogenesis is not associated with virulent, unmodified, bluetongue virus.The articles have been scanned in colour with a HP Scanjet 5590; 300dpi. Adobe Acrobat XI Pro was used to OCR the text and also for the merging and conversion to the final presentation PDF-format

A Comprehensive Pan-Cancer Molecular Study of Gynecologic and Breast Cancers

We analyzed molecular data on 2,579 tumors from The Cancer Genome Atlas (TCGA) of four gynecological types plus breast. Our aims were to identify shared and unique molecular features, clinically significant subtypes, and potential therapeutic targets. We found 61 somatic copy-number alterations (SCNAs) and 46 significantly mutated genes (SMGs). Eleven SCNAs and 11 SMGs had not been identified in previous TCGA studies of the individual tumor types. We found functionally significant estrogen receptor-regulated long non-coding RNAs (lncRNAs) and gene/lncRNA interaction networks. Pathway analysis identified subtypes with high leukocyte infiltration, raising potential implications for immunotherapy. Using 16 key molecular features, we identified five prognostic subtypes and developed a decision tree that classified patients into the subtypes based on just six features that are assessable in clinical laboratories. By performing molecular analyses of 2,579 TCGA gynecological (OV, UCEC, CESC, and UCS) and breast tumors, Berger et al. identify five prognostic subtypes using 16 key molecular features and propose a decision tree based on six clinically assessable features that classifies patients into the subtypes

Étude (par l’inhibition «in vitro » de la migration des macrophages) de l’hypersensibilité retardée dans l’infection expérimentale du cobaye à Herpesvirus bovis (virus I. B. R./I. P. V.)

Faye P., Charton André, Mc Kercher D. G., Le Layec Cl., Solsona M., Gueslin M. Etude (par l’inhibition «in vitro» de la migration des macrophages) de l’hypersensibilité retardée dans l’infection expérimentale du cobaye à Herpesvirus bovis (virus I. B.R./I. P.V.). In: Bulletin de l'Académie Vétérinaire de France tome 128 n°6-7, 1975. pp. 319-323