The Bitter Pill: How Second-Wave Feminism Failed, and Why It Doesn\u27t Matter

It\u27s not cool to be a feminist. It’s not anti-establishment to say you don’t identify with that label; now, it’s the status quo. Every time a celebrity like Katy Perry or Salma Hayek distances herself from feminism, blogs like Jezebel and Feministing pounce. But a few months ago I found out that all the back-and-forth doesn’t matter. The final verdict on second-wave feminism\u27s success won’t be found in words spoken on the red carpet or in rejoinders on women’s blogs. The future of gender relations will be decided in an obscure corner of the Internet populated primarily by angry white men

The Role of the Physical Therapist in Health Promotion as Perceived by Patients with Neurological Pathologies: A Descriptive Study

Background and Purpose: Patients with neurological pathologies have been found to be less likely to engage in personal health behaviors than the general population. This predisposes them to acquire secondary chronic conditions such as obesity, diabetes, and cardiovascular disease. Studies suggest that this population may be underserved in regards to the promotion of health behaviors. Literature is lacking regarding neurological patients’ perspectives of the physical therapist’s role in promoting personal health behaviors. The purpose of this study was to investigate the perceptions of patients with neurological disability regarding the physical therapist’s role in promoting the personal health behaviors of physical activity, healthy weight management, smoking cessation, and fruit and vegetable consumption. Methods: A convenience sample of patients from a Minneapolis area outpatient rehabilitation center was obtained by physical therapist referral. Surveys were distributed to patients who met the inclusion criteria. The survey obtained information regarding the patient’s perception of what the role of the physical therapist should be for each personal health behavior. Data were analyzed using Microsoft Excel 2013. Results: Thirty-five surveys met inclusion criteria and were analyzed. Respondents’ demographics were as follows: mean age of 52.3±16.7years, 62.9% were male, average BMI of 28.1 ± 6.6 and 73.5% reported having a neurological condition for at least 3 years. A key finding was that 76% of respondents believe that physical therapists should suggest ways to maintain a healthy weight, however it was only addressed with 37% of the sample. The majority of respondents believed physical therapists should advise them about physical activity (88.6%), smoking cessation (65%), and weight management (83%). Conclusion: Overall, respondents with chronic neurological conditions in an outpatient setting who were surveyed expressed the belief that physical therapists should advise them in the personal health behaviors of physical activity, weight management, smoking cessation, and fruit and vegetable intake. Although the majority of respondents believed weight management should be discussed in their therapy sessions, only 37% reported their physical therapist addressed their weight. This finding suggests a potential opportunity for physical therapists to have conversation with their patients on healthy weight management

Department of Pathology History

This departmental history was written on the occasion of the UND Quasquicentennial in 2008.https://commons.und.edu/departmental-histories/1105/thumbnail.jp

Surface deoxidation mechanism during vacuum heat treatment of stainless steels AISI 304 and 446

A process of removal of surface oxides from stainless steels AISI 304 and 446 that involves reduction by residual carbon, followed by the formation and desorption of carbon monoxide, is studied by investigation of thermal desorption with quadrupole mass spectrometry (QMS) and secondary ion mass spectrometry (SIMS). Carbon monoxide desorption is studied as a function of time and temperature by QMS, and carbon diffusion due to heat treatment is studied with SIMS—twice as much carbon monoxide desorbs from AISI 304 overall and desorption sets in at 900 °C as opposed to 1100 °C for AISI 446. In samples heated to 900 °C, carbon shows surface enrichment in AISI 304 but depletion in AISI 446

Combined TLR and CD40 Triggering Induces Potent CD8+ T Cell Expansion with Variable Dependence on Type I IFN

Toll-like receptors are important in the activation of innate immunity, and CD40 is a molecule critical for many T and B cell responses. Whereas agonists for either pathway have been used as vaccine adjuvants, we show that a combination of Toll-like receptor (TLR)7 and CD40 agonists synergize to stimulate CD8+ T cell responses 10–20-fold greater than the use of either agonist alone. Antigen-specific CD8+ T cells elicited from combination CD40/TLR7 treatment demonstrated both lytic activities and interferon (IFN)γ production and an enhanced secondary response to antigenic challenge. Agonists for TLRs 2/6, 3, 4, and 9 also synergized with CD40 stimulation, demonstrating that synergy with the CD40 pathway is a property of TLR-derived stimuli in general. The CD8+ T cell expansion induced by CD40/TLR7 triggering was independent of CD4+ T cells, IFNγ, and IL-12 but dependent on B7-mediated costimulation and surprisingly on type I IFN. These studies provide the rational basis for the use of TLR and CD40 agonists together as essential adjuvants to optimize vaccines designed to elicit protective or therapeutic immunity

Comparison of inpatient psychiatric medication management in gender diverse youth with cisgender peers

Introduction The primary objective was to determine if gender diverse (GD) youth receive different psychotropic prescribing compared with cisgender (CG) peers with the same diagnosis. Secondary objectives include evaluation of readmission rates and the effect of gender-affirming hormone therapy (GAHT) on psychiatric outcomes in transgender (TG) patients. Methods A total of 255 GD youth patients were retrospectively matched to CG controls based on age, primary discharge diagnosis, and year of admission. Data collection included psychotropic medications at admission and discharge, baseline demographics, time to readmission, and total number of readmissions within 6 months. Use of GAHT was also documented. Wilcoxon signed rank test was used for continuous and χ2 for nominal data with an a priori α of 0.05. Results MDD was the primary discharge diagnosis in 74% of patients. GD youth were more likely to present on antidepressants (P = .031) and antipsychotics (P = .007), and to be discharged with antipsychotics (P = .003). They were additionally more likely to be readmitted within 30 days of discharge (P = .032). TG youth on GAHT (13%) had fewer readmissions (P = .046) than those not on GAHT, but there were no differences in psychotropic prescribing. Discussion Higher antipsychotic and antidepressant prescribing were seen in the GD population despite the same mental health diagnosis. Despite higher prescribing in the GD population, patients presented for readmission within 30 days more frequently, which may represent a need for more rigorous transitions-of-care practices in this population

Prioritisation of patients on waiting lists for hip and knee arthroplasties and cataract surgery: Instruments validation

<p>Abstract</p> <p>Background</p> <p>Prioritisation instruments were developed for patients on waiting list for hip and knee arthroplasties (AI) and cataract surgery (CI). The aim of the study was to assess their convergent and discriminant validity and inter-observer reliability.</p> <p>Methods</p> <p>Multicentre validation study which included orthopaedic surgeons and ophthalmologists from 10 hospitals. Participating doctors were asked to include all eligible patients placed in the waiting list for the procedures under study during the medical visit. Doctors assessed patients' priority through a visual analogue scale (VAS) and administered the prioritisation instrument. Information on socio-demographic data and health-related quality of life (HRQOL) (HUI3, EQ-5D, WOMAC and VF-14) was obtained through a telephone interview with patients. The correlation coefficients between the prioritisation instrument score and VAS and HRQOL were calculated. For the reliability study a self-administered questionnaire, which included hypothetic patients' scenarios, was sent via postal mail to the doctors. The priority of these scenarios was assessed through the prioritisation instrument. The intraclass correlation coefficient (ICC) between doctors was calculated.</p> <p>Results</p> <p>Correlations with VAS were strong for the AI (0.64, CI95%: 0.59–0.68) and for the CI (0.65, CI95%: 0.62–0.69), and moderate between the WOMAC and the AI (0.39, CI95%: 0.33–0.45) and the VF-14 and the CI (0.38, IC95%: 0.33–0.43). The results of the discriminant analysis were in general as expected. Inter-observer reliability was 0.79 (CI95%: 0.64–0.94) for the AI, and 0.79 (CI95%: 0.63–0.95) for the CI.</p> <p>Conclusion</p> <p>The results show acceptable validity and reliability of the prioritisation instruments in establishing priority for surgery.</p

A test of the implicit tax hypothesis: the ARTC experience

Bibliography: p. 60-63

Nigral neuropathology of Parkinson's motor subtypes coincide with circuitopathies: a scoping review

The neuropathological substrates of Parkinson's disease (PD) patients with motor subtypes tremor-dominance (TD), non-tremor dominance (nTD), postural instability and gait difficulty (PIGD), and akinetic-rigid (AR) are not completely differentiated. While extensive pathological research has been conducted on neuronal tissue of PD patients, data have not been discussed in the context of mechanistic circuitry theories differentiating motor subtypes. It is, therefore, expected that a more specific and tailored management of PD symptoms can be accomplished by understanding symptom-specific neuropathological mechanisms with the detail histology can provide. This scoping review gives an overview of the literature comparing TD and nTD PD motor subtypes by clarify observed pathology with underlying physiological circuitry theories. Studies using an array of pathological examination techniques have shown significant differences between TD and nTD PD subtypes. nTD PD patients show higher neuronal loss, gliosis, extraneuronal melanin deposits, and neuroaxonal dystrophy in multiple subregions of the substantia nigra (SN) related to the overactivity of the indirect motor loop. TD patients show more severe cell loss specifically in medial SN subdivisions, and have damage in the retrorubral field A-8 that projects to the dorsolateral striatum and ventromedial thalamus in the direct motor loop. Pathological studies are consistent with neuroimaging data and support contemporary mechanistic circuitry theories of PD motor symptom genesis. Further multimodal neuroimaging and histological studies are required to validate and expand upon these findings