Clinical pharmacogenetics implementation consortium (CPIC) guidelines for human leukocyte antigen B (HLA-B) genotype and allopurinol dosing: 2015 update

The Clinical Pharmacogenetics Implementation Consortium (CPIC) Guidelines for HLA-B*58:01 Genotype and Allopurinol Dosing was originally published in February 2013. We reviewed the recent literature and concluded that none of the evidence would change the therapeutic recommendations in the original guideline; therefore, the original publication remains clinically current. However, we have updated the Supplemental Material and included additional resources for applying CPIC guidelines into the electronic health record. Up-to-date information can be found at PharmGKB (http://www.pharmgkb.org)

An exploratory comparison of e-commerce adoption in large and small enterprises

This study compares the reasons why small and large companies are adopting electronic commerce (e-commerce) and compares the benefits realized from the adoption of e-commerce by these two groups of companies. Two surveys that were undertaken contemporaneously on the use of e-commerce by small and large companies in the UK were used as the empirical basis for this study. The study found that the use of e-commerce for responding to competitors, providing enhanced customer services and improving relations with suppliers was driving the uptake by smaller businesses to a greater extent than by their larger counterparts. Only in the area of improved operational efficiency did larger businesses express greater interest in adopting e-commerce. The study also found that smaller businesses believed that they had achieved greater benefits from their e-commerce services than had the larger firms in all areas explored

Incorporation of Pharmacogenomics into Routine Clinical Practice: the Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline Development Process

Personalised Therapeutic

Third Universal Definition of Myocardial Infarction

Cardiolog