117 research outputs found
HIV Disease: Criminal and Civil Liability for Assisted Suicide
This article first traces the evolution of attitudes and subsequent laws regarding suicide and assisted suicide. Secondly, the criminal and civil liability of assisted suicide is assessed on the basis of California case law. Lastly, this paper will discuss the applicability of the defenses of the right of privacy and the right of autonomy to acts of suicide and assisted suicide. This discussion will focus on the right of a person with HIV disease to enlist the assistance of the medical profession to make his or her death as quick and as painless as possible, a practice which under the current law could be classified as murder. The paper will conclude with an assertion that the charges of murder, voluntary manslaughter, and aiding and abetting a rational suicide should not apply to true mercy killing. Concomitantly, civil suits and other laws affecting the administration and disposition of the estate or insurance proceeds should likewise not apply to true mercy killing
A Racial Impact Analysis of HB 462
The adoption of House Bill 462 into law brings forth questions about the probable impact on the physical, mental, emotional and financial well-being of the women in Virginia. In particular, analysis of its effect on the minority and underserved female population is required. Understanding the origin of this new legislation and the thinking behind its proposal and subsequent adoption dictates an endeavor into the backgrounds and intended goals of its sponsors and supporters. Proponents of HB 462 were unresponsive to requests for an interview to expound on their perspective about the importance of the legislation. This precipitated the use of media clips from televised political discussions and newspaper articles to acquire direct quotes in an effort to gain insight into their position. Legislation of morality emerged as the key them from the research materials assembled. This belief is shared by many who oppose the law.
The Supreme Court put forth the following as the reasoning behind its decision, in Planned Parenthood v. Casey: “Some of us as individuals find abortion offensive to our most basic principles of morality, but that cannot control our decision. Our obligation is to define the liberty of all, not to mandate our own moral code...at the heart of liberty is the right to define one\u27s own concept of existence, of meaning, of the universe, and of the mystery of human life.” Opponents of HB 462 regard the law as contrary to the decision. If, in fact, this legislation is not intended to impose the morality of its sponsors on all Virginians, as the research suggests, it is probable that it will have a disparate impact on the minority and underserved segment of the population
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Preliminary Results of American Eel Sampling Efforts in Gulf of Mexico Drainages of Texas
American Eel Anguilla rostrata has a unique and complex life history that is fairly well-studied on the eastern coast of the United States, but few studies have been done on Gulf of Mexico drainages. To inform conservation and management decisions, efforts to better understand the population structure, seasonal dynamics, and life history of American Eel are underway. The primary objectives of our efforts are to assess the current and historical distribution and abundance, habitat use, movement patterns, parasite occurrence, diet and population structure of American Eel across all life stages in Gulf of Mexico drainages of Texas.Texas State Wildlife Grant Program grants T-173-R-1 and T-172-R-1 in cooperation with the U.S. Fish and Wildlife Service, Wildlife and Sport Fish Restoration ProgramIntegrative Biolog
ACMiner: Extraction and Analysis of Authorization Checks in Android's Middleware
Billions of users rely on the security of the Android platform to protect
phones, tablets, and many different types of consumer electronics. While
Android's permission model is well studied, the enforcement of the protection
policy has received relatively little attention. Much of this enforcement is
spread across system services, taking the form of hard-coded checks within
their implementations. In this paper, we propose Authorization Check Miner
(ACMiner), a framework for evaluating the correctness of Android's access
control enforcement through consistency analysis of authorization checks.
ACMiner combines program and text analysis techniques to generate a rich set of
authorization checks, mines the corresponding protection policy for each
service entry point, and uses association rule mining at a service granularity
to identify inconsistencies that may correspond to vulnerabilities. We used
ACMiner to study the AOSP version of Android 7.1.1 to identify 28
vulnerabilities relating to missing authorization checks. In doing so, we
demonstrate ACMiner's ability to help domain experts process thousands of
authorization checks scattered across millions of lines of code
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The effects of COVID-19 lockdown measures on health and healthcare services in Uganda
Many countries across the world instituted lockdowns as a measure to prevent the spread of COVID-19. However, these lockdowns had consequences on health systems. This study explored effects of the COVID-19 lockdown measures on health and healthcare services in Uganda. The qualitative study employed focus group discussions (FGDs), household interviews, and key informant interviews (KIIs) in both an urban (Kampala district) and rural (Wakiso district) setting in central Uganda. Fourteen FGDs were conducted among community members, local leaders, community health workers, and health practitioners. Interviews were conducted among 40 households, while 31 KIIs were held among various stakeholders including policy makers, non-governmental organisations, and the private sector. Data was analysed by thematic analysis with the support of NVivo 2020 (QSR International). Findings from the study are presented under four themes: maternal and reproductive health; child health; chronic disease services; and mental health. Maternal and reproductive health services were negatively affected by the lockdown measures which resulted in reduced utilisation of antenatal, postnatal and family planning services. These effects were mainly due to travel restrictions including curfew, and fear of contracting COVID-19. The effects on child health included reduced utilisation of services which was a result of difficulties faced in accessing health facilities because of the travel restrictions. Patients with chronic conditions could not access health facilities for their routine visits particularly due to suspension of public transport. Depression, stress and anxiety were common due to social isolation from relatives and friends, loss of jobs, and fear of law enforcement personnel. There was also increased anxiety among health workers due to fear of contracting COVID-19. The COVID-19 lockdown measures negatively affected health, and reduced access to maternal, reproductive and child health services. Future interventions in pandemic response should ensure that their effects on health and access to health services are minimised
Pathways to Occupational Therapy: Experiences of LGBTQIA+ Practitioners
The poster was created by Masters of Occupational Therapy students for their OCCT 992:Applied Research course. Students interviewed occupational therapy practitioners who identified as part of the LGBTQIA+ community to explore there trajectory to the disciplin
Climate and plant controls on soil organic matter in coastal wetlands
Coastal wetlands are among the most productive and carbon‐rich ecosystems on Earth. Long‐term carbon storage in coastal wetlands occurs primarily belowground as soil organic matter (SOM). In addition to serving as a carbon sink, SOM influences wetland ecosystem structure, function, and stability. To anticipate and mitigate the effects of climate change, there is a need to advance understanding of environmental controls on wetland SOM. Here, we investigated the influence of four soil formation factors: climate, biota, parent materials, and topography. Along the northern Gulf of Mexico, we collected wetland plant and soil data across elevation and zonation gradients within 10 estuaries that span broad temperature and precipitation gradients. Our results highlight the importance of climate–plant controls and indicate that the influence of elevation is scale and location dependent. Coastal wetland plants are sensitive to climate change; small changes in temperature or precipitation can transform coastal wetland plant communities. Across the region, SOM was greatest in mangrove forests and in salt marshes dominated by graminoid plants. SOM was lower in salt flats that lacked vascular plants and in salt marshes dominated by succulent plants. We quantified strong relationships between precipitation, salinity, plant productivity, and SOM. Low precipitation leads to high salinity, which limits plant productivity and appears to constrain SOM accumulation. Our analyses use data from the Gulf of Mexico, but our results can be related to coastal wetlands across the globe and provide a foundation for predicting the ecological effects of future reductions in precipitation and freshwater availability. Coastal wetlands provide many ecosystem services that are SOM dependent and highly vulnerable to climate change. Collectively, our results indicate that future changes in SOM and plant productivity, regulated by cascading effects of precipitation on freshwater availability and salinity, could impact wetland stability and affect the supply of some wetland ecosystem services
Mixed Chamber Ensembles
Kennesaw State University School of Music presents Mixed Chamber Ensembles, 2:00 p.m. performance.https://digitalcommons.kennesaw.edu/musicprograms/1357/thumbnail.jp
Metabolic activation of CaMKII by coenzyme A
Active metabolism regulates oocyte cell death via calcium/calmodulin-dependent protein kinase II (CaMKII)-mediated phosphorylation of caspase-2, but the link between metabolic activity and CaMKII is poorly understood. Here we identify coenzyme A (CoA) as the key metabolic signal that inhibits Xenopus laevis oocyte apoptosis by directly activating CaMKII. We found that CoA directly binds to the CaMKII regulatory domain in the absence of Ca(2+) to activate CaMKII in a calmodulin-dependent manner. Furthermore, we show that CoA inhibits apoptosis not only in X. laevis oocytes but also in Murine oocytes. These findings uncover a direct mechanism of CaMKII regulation by metabolism and further highlight the importance of metabolism in preserving oocyte viability
Crystal Structure of the PAC1R Extracellular Domain Unifies a Consensus Fold for Hormone Recognition by Class B G-Protein Coupled Receptors
Pituitary adenylate cyclase activating polypeptide (PACAP) is a member of the PACAP/glucagon family of peptide hormones, which controls many physiological functions in the immune, nervous, endocrine, and muscular systems. It activates adenylate cyclase by binding to its receptor, PAC1R, a member of class B G-protein coupled receptors (GPCR). Crystal structures of a number of Class B GPCR extracellular domains (ECD) bound to their respective peptide hormones have revealed a consensus mechanism of hormone binding. However, the mechanism of how PACAP binds to its receptor remains controversial as an NMR structure of the PAC1R ECD/PACAP complex reveals a different topology of the ECD and a distinct mode of ligand recognition. Here we report a 1.9 Å crystal structure of the PAC1R ECD, which adopts the same fold as commonly observed for other members of Class B GPCR. Binding studies and cell-based assays with alanine-scanned peptides and mutated receptor support a model that PAC1R uses the same conserved fold of Class B GPCR ECD for PACAP binding, thus unifying the consensus mechanism of hormone binding for this family of receptors
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