Critical Current Peaks at 3BΦ3B_{\Phi} in Superconductors with Columnar Defects: Recrystalizing the Interstitial Glass

The role of commensurability and the interplay of correlated disorder and interactions on vortex dynamics in the presence of columnar pins is studied via molecular dynamics simulations. Simulations of dynamics reveal substantial caging effects and a non-monotonic dependence of the critical current with enhancements near integer values of the matching field $B_{\phi}$ and $3B_{\phi}$ in agreement with experiments on the cuprates. We find qualitative differences in the phase diagram for small and large values of the matching field.Comment: 5 pages, 4 figures (3 color

A QTL for osteoporosis detected in an F2 population derived from White Leghorn chicken lines divergently selected for bone index

Osteoporosis, resulting from progressive loss of structural bone during the period of egg-laying in hens, is associated with an increased susceptibility to bone breakage. To study the genetic basis of bone strength, an F cross was produced from lines of hens that had been divergently selected for bone index from a commercial pedigreed White Leghorn population. Quantitative trait loci (QTL) affecting the bone index and component traits of the index (tibiotarsal and humeral strength and keel radiographic density) were mapped using phenotypic data from 372 F individuals in 32 F families. Genotypes for 136 microsatellite markers in 27 linkage groups covering ∼80% of the genome were analysed for association with phenotypes using within-family regression analyses. There was one significant QTL on chromosome 1 for bone index and the component traits of tibiotarsal and humeral breaking strength. Additive effects for tibiotarsal breaking strength represented 34% of the trait standard deviation and 7.6% of the phenotypic variance of the trait. These QTL for bone quality in poultry are directly relevant to commercial populations

Cholinergic suppression: A postsynaptic mechanism of long-term associative learning

Food avoidance learning in the mollusc Pleurobranchaea entails reduction in the responsiveness of key brain interneurons in the feeding neural circuitry, the paracerebral feeding command interneurons (PCNs), to the neurotransmitter acetylcholine (AcCho). Food stimuli applied to the oral veil of an untrained animal depolarize the PCNs and induce the feeding motor program (FMP). Atropine (a muscarinic cholinergic antagonist) reversibly blocks the food-induced depolarization of the PCNs, implicating AcCho as the neurotransmitter mediating food detection. AcCho applied directly to PCN somata depolarizes them, indicating that the PCN soma membrane contains AcCho receptors and induces the FMP in the isolated central nervous system preparation. The AcCho response of the PCNs is mediated by muscariniclike receptors, since comparable depolarization is induced by muscarinic agonists (acetyl-ß -methylcholine, oxotremorine, pilocarpine), but not nicotine, and blocked by muscarinic antagonists (atropine, trifluoperazine). The nicotinic antagonist hexamethonium, however, blocked the AcCho response in four of six cases. When specimens are trained to suppress feeding behavior using a conventional food-avoidance learning paradigm (conditionally paired food and shock), AcCho applied to PCNs in the same concentration as in untrained animals causes little or no depolarization and does not initiate the FMP. Increasing the concentration of AcCho 10-100 times, however, induces weak PCN depolarization in trained specimens, indicating that learning diminishes but does not fully abolish AcCho responsiveness of the PCNs. This study proposes a cellular mechanism of long-term associative learning -- namely, postsynaptic modulation of neurotransmitter responsiveness in central neurons that could apply also to mammalian species

Grepafloxacin Versus Cefixime as Single-Dose Therapy for Uncomplicated Gonorrhea in Women

Objective: To compare the efficacy and tolerance of single-dose grepafloxacin with cefixime for treatment of uncomplicated gonorrhea in women

Evaluation of linear ozone photochemistry parametrizations in a stratosphere-troposphere data assimilation system

This paper evaluates the performance of various linear ozone photochemistry parametrizations using the stratosphere-troposphere data assimilation system of the Met Office. A set of experiments were run for the period 23 September 2003 to 5 November 2003 using the Cariolle (v1.0 and v2.1), LINOZ and Chem2D-OPP (v0.1 and v2.1) parametrizations. All operational meteorological observations were assimilated, together with ozone retrievals from the Michelson Interferometer for Passive Atmospheric Sounding (MIPAS). Experiments were validated against independent data from the Halogen Occultation Experiment (HALOE) and ozonesondes. Additionally, a simple offline method for comparing the parametrizations is introduced. <br><br> It is shown that in the upper stratosphere and mesosphere, outside the polar night, ozone analyses are controlled by the photochemistry parametrizations and not by the assimilated observations. The most important factor in getting good results at these levels is to pay attention to the ozone and temperature climatologies in the parametrizations. There should be no discrepancies between the climatologies and the assimilated observations or the model, but there is also a competing demand that the climatologies be objectively accurate in themselves. Conversely, in the lower stratosphere outside regions of heterogeneous ozone depletion, the ozone analyses are dominated by observational increments and the photochemistry parametrizations have little influence. <br><br> We investigate a number of known problems in LINOZ and Cariolle v1.0 in more detail than previously, and we find discrepancies in Cariolle v2.1 and Chem2D-OPP v2.1, which are demonstrated to have been removed in the latest available versions (v2.8 and v2.6 respectively). In general, however, all the parametrizations work well through much of the stratosphere, helped by the presence of good quality assimilated MIPAS observations

Cosmological gravitomagnetism and Mach's principle

The spin axes of gyroscopes experimentally define local non-rotating frames. But what physical cause governs the time-evolution of gyroscope axes? We consider linear perturbations of Friedmann-Robertson-Walker cosmologies with k=0. We ask: Will cosmological vorticity perturbations exactly drag the spin axes of gyroscopes relative to the directions of geodesics to quasars in the asymptotic unperturbed FRW space? Using Cartan's formalism with local orthonormal bases we cast the laws of linear cosmological gravitomagnetism into a form showing the close correspondence with the laws of ordinary magnetism. Our results, valid for any equation of state for cosmological matter, are: 1) The dragging of a gyroscope axis by rotational perturbations of matter beyond the Hubble-dot radius from the gyroscope is exponentially suppressed, where dot is the derivative with respect to cosmic time. 2) If the perturbation of matter is a homogeneous rotation inside some radius around a gyroscope, then exact dragging of the gyroscope axis by the rotational perturbation is reached exponentially fast as the rotation radius grows beyond the H-dot radius. 3) For the most general linear cosmological perturbations the time-evolution of all gyroscope spin axes exactly follow a weighted average of the energy currents of cosmological matter. The weight function is the same as in Ampere's law except that the inverse square law is replaced by the Yukawa force with the Hubble-dot cutoff. Our results demonstrate (in first order perturbation theory for FRW cosmologies with k = 0) the validity of Mach's hypothesis that axes of local non-rotating frames precisely follow an average of the motion of cosmic matter.Comment: 18 pages, 1 figure. Comments and references adde

Masculinity as Governance: police, public service and the embodiment of authority, c. 1700-1850

About the book: Public Men offers an introduction to an exciting new field: the history of masculinities in the political domain and will be essential reading for students and specialists alike with interests in gender or political culture. By building upon new work on gender and political culture, these new case studies explore the gendering of the political domain and the masculinities of the men who have historically dominated it. As such, Public Men is a major contribution to our understanding of the history of Britain between the Eighteenth and the Twentieth centuries