2,781 research outputs found
Sidereal frequency generator Patent
System generating sidereal frequency signals from signals of standard solar frequency without use of mixing operations or feedback loop
Predictive text entry in immersive environments
One of the classic problems with immersive environments is data entry; with a head-mounted display (HMD) the user can no longer see the keyboard. Although for many applications data entry is not a requirement, for some it is essential: communicating in collaborative environments, entering a filename to which work can be saved, or accessing system controls. Combining data gloves and a graphically represented keyboard with a predictive spelling paradigm, we describe an effective text entry technique for immersive environments; we explore the key issues when using such a technique, and report the results of preliminary usability testing
Sirtuins, bioageing, and cancer
The Sirtuins are a family of orthologues of yeast Sir2 found in a wide range of organisms from bacteria to man. They display a high degree of conservation between species, in both sequence and function, indicative of their key biochemical roles. Sirtuins are heavily implicated in cell cycle, cell division, transcription regulation, and metabolism, which places the various family members at critical junctures in cellular metabolism. Typically, Sirtuins have been implicated in the preservation of genomic stability and in the prolongation of lifespan though many of their target interactions remain unknown.
Sirtuins play key roles in tumourigenesis, as some have tumour-suppressor functions and others influence tumours through their control of the metabolic state of the cell. Their links to ageing have also highlighted involvement in various age-related and degenerative diseases. Here, we discuss the current understanding of the role of Sirtuins in age-related diseases while taking a closer look at their roles and functions in maintaining genomic stability and their influence on telomerase and telomere function
Measurement and calculation of forces in a magnetic journal bearing actuator
Numerical calculations and experimental measurements of forces from an actuator of the type used in active magnetic journal bearings are presented. The calculations are based on solution of the scalar magnetic potential field in and near the gap regions. The predicted forces from single magnet with steady current are compared with experimental measurements in the same geometry. The measured forces are smaller than calculated ones in the principal direction but are larger than calculated in the normal direction. This combination of results indicate that material and spatial effects other than saturation play roles in determining the force available from an actuator
Verification of the Convection-Allowing Ensemble System over the Hindu Kush Himalaya Region During the 2018 and 2019 Pre-Monsoon Severe Thunderstorm Seasons
Some of the most intense thunderstorms on the planet occur in the Hindu Kush Himalaya (HKH) region of South-Central Asia. NASA/SERVIR Applied Sciences Team competitive project to develop capacity of severe thunderstorm monitoring and forecasting tool for HKH. Project Goal: Use [NASA] modeling and remote-sensing assets to build early warning capabilities and facilitate timely disaster response for high impact weather events in the HKH region. Specific objectives: 1. Prototype and transition High-Impact Weather Assessment Toolkit (HIWAT) 2. Jointly develop HIWAT capabilities & training with SERVIRs hub in Kathmandu, Nepal: International Centre for Integrated Mountain Development (ICIMOD) 3. Demonstrate capacity in end-user environment 4. Transition HIWAT system to ICIMOD for future maintenance
Multi-center Airborne Coherent Atmospheric Wind Sensor (MACAWS)
This effort involves development of a calibrated, pulsed coherent CO2 Doppler lidar, followed by a carefully-planned and -executed program of multi-dimensional wind velocity and aerosol backscatter measurements from the NASA DC-8 research aircraft. The lidar, designated as the Multi-center Airborne Coherent Atmospheric Wind Sensor (MACAWS), will be applicable to two research areas. First, MACAWS will enable specialized measurements of atmospheric dynamical processes in the planetary boundary layer and free troposphere in geographic locations and over scales of motion not routinely or easily accessible to conventional sensors. The proposed observations will contribute fundamentally to a greater understanding of the role of the mesoscale, helping to improve predictive capabilities for mesoscale phenomena and to provide insights into improving model parameterizations of sub-grid scale processes within large-scale circulation models. As such, it has the potential to contribute uniquely to major, multi-institutional field programs planned for the mid 1990's. Second, MACAWS measurements can be used to reduce the degree of uncertainty in performance assessments and algorithm development for NASA's prospective Laser Atmospheric Wind Sounder (LAWS), which has no space-based instrument heritage. Ground-based lidar measurements alone are insufficient to address all of the key issues. To minimize costs, MACAWS is being developed cooperatively by the lidar remote sensing groups of the Jet Propulsion Laboratory, NOAA Wave Propagation Laboratory, and MSFC using existing lidar hardware and manpower resources. Several lidar components have already been exercised in previous airborne lidar programs (for example, MSFC Airborne Doppler Lidar System (ADLS) used in 1981,4 Severe Storms Wind Measurement Program; JPL Airborne Backscatter Lidar Experiment (ABLE) used in 1989,90 Global Backscatter Experiment Survey Missions). MSFC has been given responsibility for directing the overall program of instrument development and scientific measurement. The focus of current research and plans for next year are presented
Atmospheric aerosol and Doppler lidar studies
Experimental and theoretical studies were performed of atmospheric aerosol backscatter and atmospheric dynamics with Doppler lidar as a primary tool. Activities include field and laboratory measurement and analysis efforts. The primary focus of activities related to understanding aerosol backscatter is the GLObal Backscatter Experiment (GLOBE) program. GLOBE is a multi-element effort designed toward developing a global aerosol model to describe tropospheric clean background backscatter conditions that Laser Atmospheric Wind Sounder (LAWS) is likely to encounter. Two survey missions were designed and flown in the NASA DC-8 in November 1989 and May to June 1990 over the remote Pacific Ocean, a region where backscatter values are low and where LAWS wind measurements could make a major contribution. The instrument complement consisted of pulsed and continuous-wave (CW) CO2 gas and solid state lidars measuring aerosol backscatter, optical particle counters measuring aerosol concentration, size distribution, and chemical composition, a filter/impactor system collecting aerosol samples for subsequent analysis, and integrating nephelometers measuring visible scattering coefficients. The GLOBE instrument package and survey missions were carefully planned to achieve complementary measurements under clean background backscatter conditions
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