83 research outputs found
Clinical challenges and unmet needs in the management of complicated intra-abdominal infections
Representation of ethological events by basolateral amygdala neurons
The accurate interpretation of ethologically relevant stimuli is crucial for survival. While basolateral amygdala (BLA) neuronal responses during fear conditioning are well studied, little is known about how BLA neurons respond during naturalistic events. We recorded from the rat BLA during interaction with ethological stimuli: male or female rats, a moving toy, and rice. Forty-two percent of the cells reliably respond to at least one stimulus, with over half of these exclusively identifying one of the four stimulus classes. In addition to activation during interaction with their preferred stimulus, these cells signal micro-behavioral interactions like social contact. After stimulus removal, firing activity persists in 30% of responsive cells for several minutes. At the micro-circuit level, information flows from highly tuned event-specific neurons to less specific neurons, and connection strength increases after the event. We propose that individual BLA neurons identify specific ethological events, with event-specific neurons driving circuit-wide activity during and after salient events
Survey of surgical infections currently known (SOSICK): A multicenter examination of antimicrobial use from the Surgical Infection Society Scientific Studies Committee
2019 update of the WSES guidelines for management of Clostridioides (Clostridium) difficile infection in surgical patients
Clinical Challenges and Unmet Needs in the Management of Complicated Intra-abdominal Infections
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