55 research outputs found

    Perbandingan Pemberitaan Dahlan Iskan Terkait Kasus Tersangka Dugaan Korupsi Gardu Induk di Surat Kabar Riau Pos dan Tribun Pekanbaru

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    Status of the suspects dropped Jakarta Provincial Prosecutor to Dahlan Iskan in cases of suspected corruption substation on June 5, 2015. As two major newspapers that compete in Riau, Riau Pos and Tribun Pekanbaru certainly not miss to made this a national issue as a material news. Differences in background made Riau Pos and Tribun Pekanbaru tried to presented the information to the packaging of different discourse to the public in accordance with the vision and mission adopted. Therefore, this study aims to determine how the macro-structure comparison, superstructure, and microstructure news Dahlan alleged corruption cases related to the substation of Riau Pos and Tribun Pekanbaru This study used a qualitative approach to discourse analysis models Teun A Van Dijk. Data was collected by interview and documentation. The object of ten research news, consists of five news from Riau Pos and five news from Tribun Pekanbaru. Informants consisted of two people who are the newspaper editors by using purposive technique. To achieve the validity of the data in this research, researchers used triangulation. The results showed: first, the macro level Riau Pos news related to this case is the theme of the trip compared Tribun Pekanbaru legal cases that focus highlights the personal realm of Dahlan Iskan. Second, the level of the superstructure showed that Riau Pos trying to establish a pattern of reporting the case that the determination of Dahlan as a suspect by the Prosecutor not through legal channels in accordance with the Criminal Procedure Code Tribune Pekanbaru different from that formed schema that figure Dahlan is the figure of a brave and responsible to face the case. Thirdly, the micro level showed that Riau Pos shows the tendency preaching through background polemics reveal detailed legal case through news stories than the Tribune Pekanbaru better preserve the independence proclamation by taking background information from the parties that is quite neutral in dealing with this case.Keywords : News Comparison, Dahlan Iskan , Substation, Alleged Suspect, CorruptionCas

    Pengaruh Return On Equity, Net Profit Margin dan Ukuran Perusahaan terhadap Underpricing

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    Salah satu cara Perusahaan untuk mengembangkan USAhanya yaitu dengan cara ekspansi dengan melakukan Initial Public Offering (IPO). Fenomena menarik pada saat Perusahaan melakukan Initial Public Offering adalah fenomena Underpricing. Fenomena underpricing merupakan fenomena dimana harga saham yang ditawarkan pada pasar perdana lebih rendah dibandingkan dengan harga saham ketika diperdagangkan di pasar sekunder. Tujuan penelitian ini adalah menganalisis pengaruh Return On Equity (ROE), Net Profit Margin (NPM) dan Ukuran Perusahaan (Firm Size) terhadapunderpricing. Populasi dalam penelitian ini adalah Perusahaan yang melakukanInitial Public Offering (IPO) di BEI tahun 2013-2016. Pemilihan sampel dalam penelitian ini menggunakan metode purposive sampling dan diperoleh 54 sampel Perusahaan dari 82 Perusahaan yang melakukan initial public offeringdi BEI tahun 2013-2016. Metodeanalisis data menggunakan regresi linear berganda. Hasil penenlitian menunjukkan bahwa Return On Equity (ROE) dan Ukuran Perusahaan (Firm Size)berpengaruh terhadap underpricing pada Perusahaan yang IPO di Bursa Efek Indonesia. Sedangkan Net Profit Margin (NPM) tidak berpengaruh underpricing pada Perusahaan yang IPO di Bursa Efek Indonesia

    Pendugaan Parameter Genetik Populasi F3 Dan F4 Tanaman Gandum Persilangan Oasis X HP1744

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    The study was aimed to obtain the information on the genetic diversity on agronomic traits of wheat among the F3 and F4 generations, derived from crosses of Oasis x HP1744, planted at the highland and medium elevation. The second objective was to acquire the character for selection and to acquire the adaptable genotypes on the highland and on the plain medium elevation. Selection was carried out using Shuttle Breeding, where F3 generation was selected at the Experimental Station of Cipanas (1100 m asl) and F4 generation was selected at the plain medium elevation of Cisarua (600 m asl). The experiment used Augmented Designs. Genetic material consisted of 57 F3 pedigree families selected from the F2 generation of Oasis x HP1744 cross plus six check varieties. The F4 generation cinsisted 320 selected genotypes from the F3 generation plus six check varieties. Plant height, flag leaf area, percentage of empty florets per panicle, number of grains/panicle and grain weight/panicle of the F3 generation showed larger mid value than the two parents. In the F4 generation, flag leaf greenness, total number of tillers, number of productive tillers, main panicle seed weight, number of seeds/panicle, seed weight/panicle, number of seeds/plant and seed weight/plant indicated the mean value larger than that of the Oasis. Plant height, number of productive tillers, days to flowering, maturity, spikelet number, and the total number of florets of the F4 generation showed higher heritability than that of F3 generation. Character suitable for indirect selection in the F3 was plant height, which indicated the best indirect differential selection. Potential families for further selection included: O/HP 21, O/HP 82, O/HP 12, O/HP 100 and O/HP 28. Characters most suitable for indirect selection in the F4 generation were: main panicle seed weight which indicated the best indirect differential selection. Genotypes potential for further selection in the medium elevation were O/HP82-19; O/HP82-15, O/HP78-5, O/HP49-30 and O/HP78-2

    PROFIL RUMAH MAKAN CAFE 57 FU DI KELURAHAN TALIKURAN KECAMATAN KAWANGKOAN UTARA KABUPATEN MINAHASA

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    CAFE 57 FU RESTAURANT PROFILE IN THE VILLAGE OF TALIKURAN KAWANGKOAN SUBDISTRICTMINAHASA REGENCY.The purpose of this study was to determine the business profile of Casfe 57 FU restaurant. This Study uses a case study method in the Cafe 57 Fu restaurant business in Talikuran Subdistrict, Kawangkoan Utara Distric on December 1, 2018 until January 31 2019. Datacollection was done by survey method using aa questionnaier and analyzed descriptively to describe the profile of the restaurant business Cafe 57 FU. The results obtained that the characteristics of respondents businessman restaurant Cafe 57 Fu was in productive age, had a high education, had 14 years of entrepreneurial experience, and had 4 household members who support the work of managing a restaurant. The Cafe 57 FU restaurant had a favorite regional food menu, Roasted Pork and Crispy Pork, so that the use of pork for processing was greater than other meat of 1.350 kg / month and restaurant 57 Fu gets a profit in a month of IDR. 23.133.24

    Hubungan Persalinan Prematur dengan Kejadian Asfiksia Neonatorum di Ruang Bersalin RSU Dr. Wahidin Sudiro Husodo Kota Mojokerto

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    Background: Persalinan prematur merupakan masalah yang selalu menjadi perhatian karena menjadi salah satu penyebab utama kematian neonatal. Persalinan prematur adalah persalinan yang terjadi ketika usia kehamilan belum mencapai 37 minggu. Persalinan prematur menjadi penyebab tingginya angka kematian bayi (AKB) karena kondisi bayi yang masih lemah karena imaturitas organ, salah satunya adalah paru-paru.Purpose: Tujuan penelitian ini adalah mengetahui adakah hubungan persalinan prematur dengan kejadian asfiksia neonatorum.Method: Desain penelitian yang digunakan adalah Cross-Sectional, yaitu suatu jenis penelitian yang menekankan pada waktu pengukuran/observasi data variabel independen dan variabel dependen hanya satu kali dalam satu saat. Dalam penelitian ini sampel diambil dengan teknik consecutive sampling, variabel dalam penelitian ini ada 2 yaitu variabel independent (variabel bebas) adalah persalinan prematur dan variabel dependent (variabel tergantung) adalah kejadian asfiksia neonatorum. Cara pengambilan data dengan menggunakan lembar observasi secara langsung kepada responden. Pengolahan data menggunakan uji korelasi Spearman.Results: Hasil penelitian menunjukkan bahwa hubungan persalinan prematur dengan kejadian asfiksia neonatorum yaitu asfiksia ringan terjadi pada 4 bayi (100%) yang dilahirkan oleh ibu yang mengalami persalinan dengan usia kehamilan 32-36 minggu. Dengan menggunakan uji Korelasi Spearman dengan tingkat kemaknaan/signifikasi 0,00 (α<0.05), yang berarti bahwa Ho ditolak dan Hi diterima. Serta didapatkan hasil koofisien korelasi (ρ) = 0,875, yang menyatakan bahwa terdapat hubungan sangat kuat antara dua variabel yaitu persalinan prematur dengan kejadian asfiksia neonatorum.Conclusion: Berdasarkan hasil penelitian, ibu hamil dan keluarga diharapkan untuk teratur melakukan kunjungan ANC, serta bagi tenaga kesehatan untuk mempertahankan pro aktif dalam memberikan ANC Terpadu, sehingga resiko dapat terdeteksi lebih awal dan komplikasi akan mendapat penanganan secepatnya

    Kepatuhan Masyarakat terhadap Pengobatan Massal Filariasis di Kabupaten Belitung Timur Tahun 2008

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    . Mass Drug Administration (MDA) was conducted in Belitung Timur Regency from 2006 to 2007. The research was conducted to evaluation the MDA program I 2008. The number of people examined from 4 village were 2.064 people and out of this number 3 people were mf positive with the Mf rate was 0.15%. Compare with the result before this study, we find out that there are descent Mf rate from 2.52% in 2005 (before MDA) to 0.15% in 2008 (after MDA). The coverage of MDA in 2006 were 97.58% and decrease to 95.44% in 2007. The knowledge, attitude and perception of the respondents were generally moderate toward filarial transmission, but there are 17 respondents (4.4%) from 385 respondents was not receiving filarial drug when the MDA was going on. There are 14 respondents (3.6%) didn't take the drug, the reason of respondents were: didn't sick, confused, and fever

    Deteksi Antibodi terhadap Mycoplasma gallisepticum pada Serum Ayam dengan Pengujian Serologi Rapid Serum Agglutination (RSA), Kit ELISA Komersil dan inhouseELISA

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    Mycoplasma gallisepticum (MG) adalah bakteri penyebab penyakit pernapasan kronis pada ayam yang sering disebut sebagai chronic respiratory disease (CRD) dan infectious sinusitis pada kalkun. Kerugian akibat infeksi MG pada industri perunggasan di dunia mencapai lebih dari US $ 780 juta setiap tahun. Deteksi dini dan monitoring secara berkelanjutan sangat dibutuhkan dari hulu yakni hatchery sampai ke hilir di peternakan komersil. Di Indonesia kasus CRD maupun CRD kompleks sampai saat ini masih menjadi permasalahan di peternakan-peternakan ayam. Keberadaan MG dapat dideteksi dengan cara isolasi organisme atau deteksi DNA dari jaringan yang terinfeksi atau sampel swab atau dengan menggunakan pengujian serologi untuk diagnosis penyakit ini. Jenis pengujian serologi yang sudah umum dilakukan adalah dengan Rapid Serum Agglutination (RSA), Enzyme-Linked Immunosorbent Assay (ELISA) dan Haemagglutination Inhibition (HI). Penelitian ini bertujuan untuk mengetahui status antibodi ayam dari beragam kondisi di lapangan dengan uji RSA, ELISA komersil dan inhouseELISA (iELISA). Pengujian serologi dengan menggunakan 3 jenis pengujian memberikan hasil yang berbeda dalam mendeteksi antibodi terhadap MG pada sampel serum ayam dengan status yang bervariasi. Kit ELISA komersil lebih sensitif dalam mendeteksi antibodi terhadap MG, sehingga pengujian ini memberikan hasil positif paling banyak

    Global economic burden of unmet surgical need for appendicitis

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    Background: There is a substantial gap in provision of adequate surgical care in many low-and middle-income countries. This study aimed to identify the economic burden of unmet surgical need for the common condition of appendicitis. Methods: Data on the incidence of appendicitis from 170 countries and two different approaches were used to estimate numbers of patients who do not receive surgery: as a fixed proportion of the total unmet surgical need per country (approach 1); and based on country income status (approach 2). Indirect costs with current levels of access and local quality, and those if quality were at the standards of high-income countries, were estimated. A human capital approach was applied, focusing on the economic burden resulting from premature death and absenteeism. Results: Excess mortality was 4185 per 100 000 cases of appendicitis using approach 1 and 3448 per 100 000 using approach 2. The economic burden of continuing current levels of access and local quality was US 92492millionusingapproach1and92 492 million using approach 1 and 73 141 million using approach 2. The economic burden of not providing surgical care to the standards of high-income countries was 95004millionusingapproach1and95 004 million using approach 1 and 75 666 million using approach 2. The largest share of these costs resulted from premature death (97.7 per cent) and lack of access (97.0 per cent) in contrast to lack of quality. Conclusion: For a comparatively non-complex emergency condition such as appendicitis, increasing access to care should be prioritized. Although improving quality of care should not be neglected, increasing provision of care at current standards could reduce societal costs substantially

    The impact of transposable element activity on therapeutically relevant human stem cells

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    Human stem cells harbor significant potential for basic and clinical translational research as well as regenerative medicine. Currently ~ 3000 adult and ~ 30 pluripotent stem cell-based, interventional clinical trials are ongoing worldwide, and numbers are increasing continuously. Although stem cells are promising cell sources to treat a wide range of human diseases, there are also concerns regarding potential risks associated with their clinical use, including genomic instability and tumorigenesis concerns. Thus, a deeper understanding of the factors and molecular mechanisms contributing to stem cell genome stability are a prerequisite to harnessing their therapeutic potential for degenerative diseases. Chemical and physical factors are known to influence the stability of stem cell genomes, together with random mutations and Copy Number Variants (CNVs) that accumulated in cultured human stem cells. Here we review the activity of endogenous transposable elements (TEs) in human multipotent and pluripotent stem cells, and the consequences of their mobility for genomic integrity and host gene expression. We describe transcriptional and post-transcriptional mechanisms antagonizing the spread of TEs in the human genome, and highlight those that are more prevalent in multipotent and pluripotent stem cells. Notably, TEs do not only represent a source of mutations/CNVs in genomes, but are also often harnessed as tools to engineer the stem cell genome; thus, we also describe and discuss the most widely applied transposon-based tools and highlight the most relevant areas of their biomedical applications in stem cells. Taken together, this review will contribute to the assessment of the risk that endogenous TE activity and the application of genetically engineered TEs constitute for the biosafety of stem cells to be used for substitutive and regenerative cell therapiesS.R.H. and P.T.R. are funded by the Government of Spain (MINECO, RYC-2016- 21395 and SAF2015–71589-P [S.R.H.]; PEJ-2014-A-31985 and SAF2015–71589- P [P.T.R.]). GGS is supported by a grant from the Ministry of Health of the Federal Republic of Germany (FKZ2518FSB403)
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