Evaluation on the effectiveness of using 3D rat model for teaching blood withdrawal technique among undergraduate students

Usage of 3D model in medical education is very important in this era as part of 21st century teaching method. Application of 3D printing model in medical education helps to improve student spatial visualization skill and also will increase their interest in difficult topic or subject specifically in the science-based issue. This study aims to evaluate the effectiveness of using a 3D rat model for teaching blood withdrawal techniques among undergraduate students. Workshop of usage of 3D model rat was conducted among all students. Students were exposure to classical teaching method of blood withdrawal and follow by workshop using 3D rat model. A set of questionnaire was given to students before and after usage of 3D- printed rat model. Data collected used a questionnaire consisting of socio-demographic, pre and post- test question and assessment towards 3D models. A total of 117 participants were tested. 3D-printed rat model was used as part of the paired sample t-test. The result supported the hypothesis that the 3D- printed rat model in teaching blood withdrawal techniques is more effective compared to the using classical teaching method in the classroom (p<0.05). Study also showed that students satisfy with usage of 3D model for teaching blood withdrawal techniques. This study further demonstrated the 3D print rat model is beneficial for interactive education and enriching student learning capacity

Evaluation an aqueous extract of irradiated and non irradiated of Orthosiphon aristatus on zebrafish embryo (Danio rerio) through acute toxicity assay

Background: Orthosiphon aristatus has been usually related to be powerful in curing many illnesses inclusive of post-partum remedy, anti-influence, rheumatism and stopping osteoporosis as a result of menopause. Objectives: Thus, this study was designed to differentiate the toxicity effect of non-irradiated and irradiated Orthosiphon aristatus at different dosage of 3, 6, 9 and 12 kilogray (kGy) on zebrafish embryo. Method: Survival rate, hatching rate, heart beat rate and scoliosis were observed and date were analysed using SPSS 25.00 windows. Result: The lethal dose (LC50) of non-irradiated Orthosiphon aristatus is 381.81 μg/mL compare to irradiated extract at 3 % is (371.27 μg/mL), 6 % (311.03 μg/mL), 9 % (160.72 μg/mL) and 12 % (140.18 μg/mL). Hatchability of zebrafish embryo for Orthosiphon aristatus extract decrease in the higher dosage of irradiated sample compared to non-irradiated sample. No presence of scoliosis was observed in all dosage of irradiated and non-irradiated of Orthosiphon aristatus. The heartbeat of zebrafish embryo treated with irradiated Orthosiphon aristatus specifically 12 % show decrease at 250 μg/mL concentration. Remaining dosage of irradiated and non-irradiated Orthosiphon aristatus show average heartbeat around 120-160 bpm. Conclusion: As conclusion, irradiated and non-irradiated of Orthosiphon aristatus is safe to be consumed due to its pharmaceutical effect but it still exhibited mild toxicity effect on zebrafish embryo